The effect of the antiherpesvirus drug 5-methoxymethyl-2'-deoxyuridine on the humoral immune response in vivo.

Abstract:

:5-Methoxymethyl-2'-deoxyuridine (MMUdR), a drug with potent antiviral activity in vitro against Herpes simplex virus, was investigated for its immunosuppressive effects. Doses as high as 2000mg/kg given daily for 9 days were not immunosupporessive as judged by the fact that treated animals produced normal immune responses to sheep erythrocytes, Brucella bacteria, and Herpes simplex virus.

journal_name

Can J Microbiol

authors

Rouse BT,Babiuk LA,Gupta VS

doi

10.1139/m77-158

subject

Has Abstract

pub_date

1977-08-01 00:00:00

pages

1059-61

issue

8

eissn

0008-4166

issn

1480-3275

journal_volume

23

pub_type

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