Abstract:
BACKGROUND:Since self-limited repair ability of the necrotic lesion may be a cause for failure of the technique, the possibility has been raised that bone marrow mononuclear cells (BMMCs) containing BMSCs implanted into a necrotic lesion of the femoral head with core decompression (CD) may be of benefit in the treatment of this condition. For this reason, we studied the implantation of the concentrated autologous bone marrow containing mononuclear cells in necrotic lesion of the femoral head to determine the effect of the method. METHODS:The study included 45 patients (59 hips, 9 females, 36 males; mean age 37.5 years, range 16-56 years) with stages I-IIIA nontraumatic avascular necrosis of the femoral head according to the system of the Association Research Circulation Osseous. Concentrated bone marrow (30-50 ml) containing mononuclear cells has been gained from autologous bone marrow (100-180 ml) obtained from the iliac crest of patient with the cell processor system. Concentrated bone marrow was injected through a CD channel into the femoral head. The outcome was determined by the changes in the Harris hip score, by progression in radiographic stages, and by the need for hip replacement. The mean follow-up was 27.6 months (range 12-40 months). RESULTS:Pre- and post-operative evaluations showed that the mean Harris hip score increased from 71 to 83. Clinically, the overall success is 79.7%, and hip replacement was done in 7 of the 59 hips (11.9%). Radiologically, 14 of the 59 hips exhibited femoral head collapse or narrowing of the coxofemoral joint space, and the overall failure rate is 23.7%. The number of BMMCs increased from 12.2 +/- 3.2 x 10(6)/ml to 35.2 +/- 12 x 10(6)/ml between pre-concentration and post-concentration. CONCLUSION:The concentrated autologous bone marrow containing mononuclear cells implantation relieves hip pain, prevents the progression of osteonecrosis. Therefore, it may be the treatment of choice particularly in stages I-II nontraumatic osteonecrosis of the femoral head.
journal_name
Arch Orthop Trauma Surgjournal_title
Archives of orthopaedic and trauma surgeryauthors
Wang BL,Sun W,Shi ZC,Zhang NF,Yue DB,Guo WS,Xu SQ,Lou JN,Li ZRdoi
10.1007/s00402-009-0939-0subject
Has Abstractpub_date
2010-07-01 00:00:00pages
859-65issue
7eissn
0936-8051issn
1434-3916journal_volume
130pub_type
杂志文章abstract:OBJECTIVE:To evaluate the clinical outcomes and radiographic results of patients who underwent single-level cervical arthroplasty using the Prestige LP. METHOD:Thirty-one patients with single-level cervical disc disease received the Prestige LP disc replacement from June 2008 to December 2009. The neck disability inde...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-013-1689-6
更新日期:2013-04-01 00:00:00
abstract:AIM:Short-stemmed prostheses are increasingly regarded as implants of first choice in primary THA. As a result of the press-fit fixation in the femoral metaphysis, the occurrence of intraoperative fractures were reported. The aim of this study was to analyze the postoperative results of the Mayo short-stem prosthesis f...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-011-1342-1
更新日期:2011-12-01 00:00:00
abstract:PURPOSE AND OBJECTIVE:Bone resection regarding adequate surgical margins is the treatment of choice for malignant bone tumors. In the case of metastasis-related complications, so-called skeletal-related events, it is highly important to achieve pain relief and a stable joint situation to re-mobilize the patients immedi...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章,评审
doi:10.1007/s00402-016-2584-8
更新日期:2017-02-01 00:00:00
abstract::Between 1973 and 1988, 108 patients with a preoperative diagnosis of spinal tuberculosis were treated by anterior extirpation and interbody fusion at Ankara University Medical Faculty, Orthopedic Surgery and Traumatology Department. In 96 cases the operations were performed intrapleurally, as Hogston described. For 12...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/BF00932444
更新日期:1989-01-01 00:00:00
abstract:PURPOSE:A potential method to relieve the pain from medial osteoarthritis of the knee is to offload the medial compartment. The Latella™ Knee Implant is a novel device designed to offload the medial compartment. The objective of the Cotera-1 study was to evaluate the preliminary safety and feasibility of the Latella im...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-020-03390-x
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Anteroposterior (AP) whole leg radiographs (WLR) in the standing position for assessment of the mechanical leg axis are generally performed preoperatively for the planning of total knee replacement (TKR) and postoperatively to assess the leg axis. The objective of the present study was to investigate whether...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-019-03256-x
更新日期:2019-10-01 00:00:00
abstract::Reamed interlocking nail through the piriformis fossa remains the golden standard for treatment of femoral shaft fracture. Fracture healing rates are 95-99%, and infection rates less than 1% (Clawson et al. in J Bone Joint Surg (Am) 53:681-692, 1971; Winquist et al. in J Bone Joint Surg (Am) 66:529-539, 1984; Brumback...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-007-0346-3
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Dynamic hip screw (DHS) osteosynthesis represents one of the most frequently performed fixation methods in orthopedic practice. The purpose of this study was to determine the potential risk of vascular damage by DHS side-plate screws (PS) and plunging instruments for individual femoral vessels and screw posi...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-018-3077-8
更新日期:2019-03-01 00:00:00
abstract::We wanted to prove the hypothesis that calcified deposits within the rotator cuff tendons are merely an epiphenomenon of complex morphological alterations in the shoulders of patients with shoulder pain and dysfunction. The shoulders of 92 patients with calcified deposits within the rotator cuff tendons as noted on pl...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s004020000255
更新日期:2001-07-01 00:00:00
abstract::The occurrence of anomalous muscles in the hand is rare, and therefore the clinician frequently does not account for their existence when reaching the diagnosis and concluding the cause of carpal tunnel syndrome. This case report describes the highly unusual case of the occurrence of bilateral flexor digitorum superfi...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-009-0826-8
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:Serial dilation of the bone tunnel has been reported to create a tighter graft-tunnel fit. It was hypothesized that a serial dilation of the femoral bone tunnel would increase the initial fixation strength in press-fit anterior cruciate ligament (ACL) reconstructive surgery. MATERIALS AND METHODS:Initial ...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-006-0206-6
更新日期:2007-11-01 00:00:00
abstract::Wrist endoprosthesis is still an exceptional indication compared to the prosthesis of large joints, especially when a rescue surgery procedure of the wrist is no longer possible and the complete wrist arthrodesis is to be considered the ultima ratio. However, a suspended function in the wrist is accompanied by a signi...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-020-03593-2
更新日期:2020-12-01 00:00:00
abstract::A case of painful junctura tendinum of the hand extensors is presented. This rare condition may have developed because of anatomical factors, including the type of connection and location of the junctura, and because of the unique position that the fingers assume during bowling. ...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s004020050275
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:There is a lack of consensus regarding appropriate criteria attesting patient's unrestricted sports activities after ACL reconstruction. The purpose of this study was to perform a survey among experienced arthroscopic surgeons regarding their return to play guidelines in these patients. METHODS:A six-item ques...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-013-1746-1
更新日期:2013-07-01 00:00:00
abstract:INTRODUCTION:Our report shows a rare case of suprascapular nerve palsy due to a SLAP-related ganglion cyst resulting in isolated weakness of the infraspinatus muscle. CASE REPORT:We report on a 31-year old volleyball player with severe shoulder pain. A ganglion cyst was excised in an open procedure and was completely ...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-005-0067-4
更新日期:2006-11-01 00:00:00
abstract:INTRODUCTION:This study was a systematic review comparing the clinical outcomes of nonsurgical and surgical management for distal radius fractures. MATERIALS AND METHODS:A comprehensive literature search was conducted using multiple databases, including Medline, Embase, and Cochrane. All databases were searched from t...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章,meta分析
doi:10.1007/s00402-020-03487-3
更新日期:2020-08-01 00:00:00
abstract::Generally, aneurysmal bone cyst is considered to be a benign lesion that occurs rarely. Its etiology and treatment vary considerably, but curettage and grafting is the widely accepted treatment. Due to the nature of the disease recurrence is always expected. It rarely regresses and we report here a case that showed an...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/BF00662291
更新日期:1993-01-01 00:00:00
abstract:INTRODUCTION:It is still controversial whether adjacent level compression fractures after balloon kyphoplasty (BK) and vertebroplasty (VP) should be regarded as the consequence of stiffness achieved by augmentation with bone cement or if the adjacent level fractures are simply the result of the natural progression of o...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-010-1106-3
更新日期:2010-09-01 00:00:00
abstract::Due to its hollow construction, which gives it elasticity, the Cenos hollow stem (Artos) reduces stress shielding in the intertrochanteric region and reduces bone remodelling at the distal tip after implantation of a cementless stem in the femoral canal. This should contribute to a longer implant survival time and red...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/BF00441616
更新日期:1994-01-01 00:00:00
abstract:INTRODUCTION:The study objective was to ascertain the incidence of bleeding and ischemic complications related to acute and planned orthopedic surgery in patients with known cardiovascular diseases. MATERIALS AND METHODS:The study conducted between 2010 and 2013 enrolled 477 patients (289 women, 188 men) with a diagno...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 临床试验,杂志文章
doi:10.1007/s00402-016-2468-y
更新日期:2016-07-01 00:00:00
abstract::A number of complications are associated with shoulder arthroscopic surgery. However rare, respiratory complications such as pneumomediastinum and related tension pneumothorax as well as spontaneous pneumothorax in patients undergoing shoulder arthroscopy by endotracheal intubation have been reported in the literature...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-008-0593-y
更新日期:2009-03-01 00:00:00
abstract:INTRODUCTION:Over time, the need for anatomic anterior cruciate ligament (ACL) to restore normal kinematics and postoperative function of the knee has been accepted. The purpose of this study was to compare the sagittal alignment of reconstructed ACL, which is performed between transtibial (TT) technique and accessory ...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-012-1498-3
更新日期:2012-07-01 00:00:00
abstract::The activation of nuclear factor (NF)-kappaB contributes to the dysfunctional inflammatory response accompanying resuscitation from hemorrhagic shock (HS), in part through induction of pro-inflammatory cytokines including granulocyte colony-stimulating factor (G-CSF) and interleukin (IL)-6. In previous studies, we dem...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s004020100337
更新日期:2002-02-01 00:00:00
abstract::Dedifferentiated chondrosarcoma (DDCS) comprises approximately 10% of all chondrosarcomas and has the worst outcome with 5-year survival of 10%. The preferred localizations are femur, humerus and pelvis. We report a case of DDCS that arose in proximal phalanx of left-hand thumb of a 66-year-old man. He was admitted wi...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-007-0538-x
更新日期:2009-02-01 00:00:00
abstract::This is a report of a 2-year follow-up of a missed posterior shoulder dislocation treated with open reduction and glenoid reconstruction with corticocancellous iliac bone autograft. In such cases, this treatment option may be an alternative to hemiarthroplasty of the shoulder. ...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-004-0693-2
更新日期:2004-07-01 00:00:00
abstract:INTRODUCTION:Freiberg disease is defined as osteochondrosis of the metatarsal head and typically occurs in adolescents with sporting activity. This study aimed to evaluate the sporting activity of young athletes after osteochondral autograft transplantation (OAT) for Freiberg disease. MATERIALS AND METHODS:OAT for Fre...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-017-2712-0
更新日期:2017-07-01 00:00:00
abstract:INTRODUCTION:Recurrent posterior glenohumeral instability poses a challenge for treatment. Bone block procedures have been advocated in cases where a bony defect is present. However, these techniques are not free of complications due to the proximity of neurovascular structures. The aim of this study is to measure the ...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-018-2986-x
更新日期:2018-12-01 00:00:00
abstract:AIM:The aim of this study is to evaluate the results of percutaneous repair of an acute AT rupture in diabetic patients. METHOD:The study included 39 subjects who were operated at our institution. We performed pre-operative evaluations the day of surgery, and report the results of post-operative evaluation at the fina...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-010-1097-0
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:To evaluate the effectiveness and safety of arthroscopic and open Bankart repair for recurrent anterior shoulder dislocation using meta-analysis of data from clinical trials. MATERIALS AND METHODS:Cochrane Register of Controlled Trials, PUBMED and EMBASE were used to search and identify clinical trials that ev...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00402-015-2175-0
更新日期:2015-04-01 00:00:00
abstract:INTRODUCTION:Inferior survival of cemented total hip arthroplasty has been reported after previous femoral osteotomy. The purpose of this study was to evaluate the long-term survival of uncemented stems after femoral osteotomy. MATERIALS AND METHODS:Forty-eight hips in 45 patients had undergone conversion THA for a fa...
journal_title:Archives of orthopaedic and trauma surgery
pub_type: 杂志文章
doi:10.1007/s00402-005-0800-z
更新日期:2005-06-01 00:00:00