Imidazolate-bridged dicopper(II) and copper(II)-zinc(II) complexes of macrocyclic ligand with methylimidazol pendants: Model study of copper(II)-zinc(II) superoxide dismutase.

abstract：:The new cyclic tetrapeptide c(HGHK) was synthesised in the solid phase and its complexes with copper(II) were studied in aqueous solution at various pH values by means of potentiometric and spectroscopic methods (UV, EPR, CD). Six mononuclear coordination species were clearly identified within the pH range 3-11. Spect...

journal_title：Journal of inorganic biochemistry

authors： Brasun J,Gabbiani C,Ginanneschi M,Messori L,Orfei M,Swiatek-Kozlowska J

更新日期：2004-12-01 00:00:00

abstract：:Aurothiomalate (AuTm) is an old, clinically established, antiarthritic gold drug that is currently being reconsidered as a candidate drug for cancer treatment and for other therapeutic indications within a more general drug repositioning program. As the biological effects of gold drugs seem to be mediated, mainly, by ...

journal_title：Journal of inorganic biochemistry

authors： Darabi F,Marzo T,Massai L,Scaletti F,Michelucci E,Messori L

更新日期：2015-08-01 00:00:00

abstract：:Arginine 56 in the beta subunit (betaArg56) of the iron-containing nitrile hydratase (NHase), one of the strongly conserved residues within the NHase family, is known to form hydrogen bonds to the sulfinyl (-SO2H) and sulfenyl (-SOH) groups of the post-translationally modified cysteine residues in the catalytic center...

journal_title：Journal of inorganic biochemistry

authors： Piersma SR,Nojiri M,Tsujimura M,Noguchi T,Odaka M,Yohda M,Inoue Y,Endo I

更新日期：2000-07-01 00:00:00

abstract：:Heme oxygenase (HO) catalyses the degradation of heme to biliverdin, carbon monoxide (CO) and ferrous iron via three successive monooxygenase reactions, using electrons provided by NADPH-cytochrome P450 reductase (CPR) and oxygen molecules. For cleavage of the oxaporphyrin ring of ferrous α-verdoheme, an intermediate ...

journal_title：Journal of inorganic biochemistry

authors： Sato H,Higashimoto Y,Sakamoto H,Sugishima M,Shimokawa C,Harada J,Palmer G,Noguchi M

更新日期：2011-02-01 00:00:00

abstract：:The importance of electrostatic interactions between buried charges in determining the properties of membrane proteins is considered. It is demonstrated that in some cases altered properties may result from the extraction of a membrane protein into an aqueous medium even when the protein conformation is unperturbed. ...

journal_title：Journal of inorganic biochemistry

authors： Moore GR,Rogers NK

更新日期：1985-03-01 00:00:00

abstract：:Measurements of binding of certain divalent cations to yeast apoenolase were made using a pH-meter, chromatography, a divalent cation electrode, and ultrafiltration. The binding of the activating metal ions Mg2+ and Co2+ and the nonactivator Ca2+ were studied as functions of the presence or absence of substrate/produc...

journal_title：Journal of inorganic biochemistry

authors： Brewer JM,Carreira LA,Collins KM,Duvall MC,Cohen C,DerVartanian DV

更新日期：1983-11-01 00:00:00

abstract：:Changes in speciation of copper(II) in reactions with epigallocatechin gallate (EGCG) and gallic acid (GA) as a function of pH have been investigated by multifrequency (X- and S-band) EPR spectroscopy in the fluid and frozen states. The EPR spectra show the formation of three distinct mononuclear species with each of ...

journal_title：Journal of inorganic biochemistry

authors： Pirker KF,Baratto MC,Basosi R,Goodman BA

更新日期：2012-07-01 00:00:00

abstract：:Nickel-containing carbon monoxide dehydrogenases, acetyl-CoA synthases, nickel-iron hydrogenases, and diron hydrogenases are distinct metalloenzymes yet they share a number of important characteristics. All are O(2)-sensitive, with active-sites composed of iron and/or nickel ions coordinated primarily by sulfur ligand...

journal_title：Journal of inorganic biochemistry

authors： Lindahl PA

更新日期：2012-01-01 00:00:00

abstract：:The study aimed to develop simple assays to study aluminium-ligand interactions in natural/biological systems where equilibrium is rarely reached and thus where the initial seconds or hours of interactions are important. The immediate and non-equilibrium precipitation of aluminium hydroxide, in aqueous solution at neu...

journal_title：Journal of inorganic biochemistry

authors： Jugdaohsingh R,Salim N,McCrohan CR,White KN,Thompson RP,Powell JJ

更新日期：2001-11-01 00:00:00

abstract：:Preparations of cis- and trans-platinum(II) complexes of diethyl (pyridin-4-ylmethyl)phosphate (4-pmOpe) have been described. These complexes were identified and characterized by far-IR, 1H NMR, 13C NMR, 31P NMR and 195Pt NMR and microanalyses. The crystal and molecular structure of trans-platinum(II) complex i.e., tr...

journal_title：Journal of inorganic biochemistry

authors： Kalinowska U,Matławska K,Checińska L,Domagała M,Kontek R,Osiecka R,Ochocki J

更新日期：2005-10-01 00:00:00

abstract：:X-ray diffraction, infrared spectroscopy and chemical investigations have been carried out on the inorganic phases from rat cortical and trabecular bone. Although both inorganic phases consist of poorly crystalline B carbonated apatite, several significant differences have been observed. In particular, trabecular bone...

journal_title：Journal of inorganic biochemistry

authors： Bigi A,Cojazzi G,Panzavolta S,Ripamonti A,Roveri N,Romanello M,Noris Suarez K,Moro L

更新日期：1997-10-01 00:00:00

abstract：:Iron deficiency anemia is a relatively common illness that can arise from a number of different causes. Three ferrous salts are usually used in its treatment: ferrous fumarate, gluconate, and sulfate. They are administered orally and are relatively well tolerated. These hematinics have been studied by Mössbauer spectr...

journal_title：Journal of inorganic biochemistry

authors： Coe EM,Bowen LH,Bereman RD

更新日期：1995-06-01 00:00:00

abstract：:Two types of polysaccharides, sulfated hyaluronic acid and heparin, were pattern-immobilized on a poly(ethylene terephthalate) and polystyrene film, respectively, in a specific pattern by photolithography. Sulfated hyaluronic acid was prepared from hylaronic acid by the treatment of sulfur trioxide/pyridine complex. H...

journal_title：Journal of inorganic biochemistry

authors： Ito Y

更新日期：2000-04-01 00:00:00

abstract：:To further develop the biomimetic chemistry of [FeFe]- and [NiFe]-hydrogenases for catalytic proton reduction to hydrogen (H2), two serials of dinuclear diiron and trinuclear NiFe2 dithiolate complexes with chelating PCNCP ligands, namely, Fe2(μ-edt)(CO)4{κ2-(Ph2PCH2)2NR} (1a-1c) and Fe2(CO)6(μ3-S)2Ni{(Ph2PCH2)2NR} (2...

journal_title：Journal of inorganic biochemistry

authors： Zhao PH,Li JR,Gu XL,Jing XB,Liu XF

更新日期：2020-09-01 00:00:00

abstract：:In heme peroxidases, a distal His residue plays an essential role in the initial two electron oxidation of resting state enzyme to compound I by hydrogen peroxide. A distal Arg residue assists in this process. The contributions of the charge, H-bonding capacity, size, and mobility of this Arg residue to Coprinus ciner...

journal_title：Journal of inorganic biochemistry

authors： Schiødt CB,Veitch NC,Welinder KG

更新日期：2007-02-01 00:00:00

abstract：:Chromomycin A(3) (CHR) and mithramycin (MTR), members of the aureolic acid anticancer antibiotics, supposedly act by inhibiting transcription via reversible association with DNA. The complex(es) with bivalent cation such as Mg(2+) and Zn(2+) is (are) the DNA-binding ligand(s). In this paper, we report a detailed study...

journal_title：Journal of inorganic biochemistry

authors： Devi PG,Pal S,Banerjee R,Dasgupta D

更新日期：2007-01-01 00:00:00

abstract：:Selenium in the form of selenocysteine plays an essential role in a number of proteins, but its role in non-enzymatic biochemistry is also important. In this short review we discuss the interactions between inorganic selenium, arsenic and mercury under physiological conditions, especially in the presence of glutathion...

journal_title：Journal of inorganic biochemistry

authors： Prince RC,Gailer J,Gunson DE,Turner RJ,George GN,Pickering IJ

更新日期：2007-11-01 00:00:00

abstract：:Transferrin, the human iron transport protein, binds Ti(IV) even more tightly than it binds Fe(III). However, the fate of titanium bound to transferrin is not well understood. Here we present results which address the fate of titanium once bound to transferrin. We have determined the redox potentials for a series of T...

journal_title：Journal of inorganic biochemistry

authors： Parker Siburt CJ,Lin EM,Brandt SJ,Tinoco AD,Valentine AM,Crumbliss AL

更新日期：2010-09-01 00:00:00

abstract：:The synthesis, characterization, and antitumor activity of a series of platinum(IV) complexes of the type DACH-PtIV(X)2Y (where DACH = trans-dl, or trans-l-1,2-diaminocyclohexane, X = OH or Cl, and Y = oxalato, malonato, methylmalonato, tartronato, ketomalonato, 1,1-cyclopropanedicarboxylato, or 1,1-cyclobutanedicarbo...

journal_title：Journal of inorganic biochemistry

authors： Khokhar AR,al-Baker S,Siddik ZH

更新日期：1994-04-01 00:00:00

abstract：:Polyoxometalates (POMs) are promising inorganic inhibitors for P-type ATPases. The experimental models used to study the effects of POMs on these ATPases are usually in vitro models using vesicles from several membrane sources. Very recently, some polyoxotungstates, such as the Dawson anion [P2W18O62]6-, were shown to...

journal_title：Journal of inorganic biochemistry

authors： Fraqueza G,Fuentes J,Krivosudský L,Dutta S,Mal SS,Roller A,Giester G,Rompel A,Aureliano M

更新日期：2019-08-01 00:00:00

abstract：:This work describes the synthesis and characterization of six new dinuclear platinum complexes having N,N'-di-(2-aminoethyl)-1,3-diamino-2-propanol, aryl substituted N-benzyl-1,4-butanediamines and N-benzyl-1,6-hexanediamines as ligands. They were prepared by the reaction of cis-[PtCl(2)(DMSO)(2)] (DMSO=dimethyl sulfo...

journal_title：Journal of inorganic biochemistry

authors： Cesar ET,de Almeida MV,Fontes AP,Pereira Maia EC,Garnier-Suillerot A,Rúbia Costa Couri M,de Castro Antunes Felício E

更新日期：2003-07-01 00:00:00

abstract：:Prion diseases are neurodegenerative disorders associated with a conformational change of the normal cellular isoform of the prion protein (PrP(C)) to an abnormal scrapie isoform (PrP(Sc)). human prion protein (hPrP(C)) is able to bind up to six Cu(II) ions. Four of them are distributed in the octarepeat domain, conta...

journal_title：Journal of inorganic biochemistry

authors： Valensin D,Padula EM,Hecel A,Luczkowski M,Kozlowski H

更新日期：2016-02-01 00:00:00

abstract：:The precursor of an RNA molecule from T4-infected E. coli cells (p2Sp1 RNA) has the capacity to cleave itself at specific positions [(UpA (139-140) and CpA (170-171)], within a putative loop and stem structure. This sequence-specific cleavage requires at least a monovalent cation and non-ionic detergents. We studied t...

journal_title：Journal of inorganic biochemistry

authors： Hosaka H,Hosono K,Kawai G,Takai K,Takaku H

更新日期：2000-11-01 00:00:00

abstract：:Folic acid is degraded by cytochrome c in the presence of hydrogen peroxide/tert-butyl hydroperoxide at the C9-N10 bond. The degradation is increased with increasing temperature. When guanidine HCl or benzoate are included in the reaction medium, the amount of folic acid degradation is enhanced. Catalase, formate, and...

journal_title：Journal of inorganic biochemistry

authors： Taher MM,Lakshmaiah N

更新日期：1987-10-01 00:00:00

abstract：:Biological studies on [Fe(L)2](NO3).0.5H2O (1), [Fe(L)2][PF6] (2), [Co(L)2](NCS) (3), [Ni(HL)2]Cl2.3H2O (4) and Cu(L)(NO3) (5), where HL=C7H8N4S, pyridine-2-carbaldehyde thiosemicarbazone, have been carried out. The crystal structure of compound 3 has been solved. It consists of discrete monomeric cationic entities co...

journal_title：Journal of inorganic biochemistry

authors： García-Tojal J,García-Orad A,Díaz AA,Serra JL,Urtiaga MK,Arriortua MI,Rojo T

更新日期：2001-04-01 00:00:00

abstract：:Bioorganometallic ferrocene-dipeptide conjugates with the Ala-Pro-cysteamine chain, Fc-L-Ala-L-Pro-NHCH2CH2SH (2) and Fc-L-Ala-D-Pro-NHCH2CH2SH (4) (Fc=ferrocenoyl), were prepared by the reduction of the ferrocene-dipeptide conjugates, Fc-L-Ala-L-Pro-cystamine-L-Pro-L-Ala-Fc (1) or Fc-L-Ala-D-Pro-cystamine-D-Pro-L-Ala...

journal_title：Journal of inorganic biochemistry

authors： Moriuchi T,Nishiyama T,Tayano Y,Hirao T

更新日期：2017-12-01 00:00:00

abstract：:Three novel copper(II) compounds of formulas {[Cu(Phen)(Ala)]·NO3·H2O}n (1), {[Cu(Phen)(Ala)]·NO3}n (2) and [Cu(Ala)2]n (3) have been synthesized and determined by X-ray diffraction. 1 and 2 are shown in one dimensional long-chain chiral structures, and 3 is a two dimensional checkerboard-type structure. Both 1 and 2 ...

journal_title：Journal of inorganic biochemistry

authors： Zhang WC,Tang X,Lu X

更新日期：2016-03-01 00:00:00

abstract：:Seven ferrocenyl naphthalene diimide (FND) ligands were synthesized. Each had a higher affinity for tetraplex DNA than for either single- or double-stranded DNA. The FND binding affinities were >105M-1 in 0.10M AcOH-AcONa or AcOH-AcOK (pH5.5) containing 0.10M NaCl or KCl. The FNDs with the highest binding affinities f...

journal_title：Journal of inorganic biochemistry

authors： Sato S,Takenaka S

更新日期：2017-02-01 00:00:00

abstract：:Vanadium compounds have arisen as potential therapeutic agent for the treatment of cancers over the past decades. A few studies suggested that vanadyl complexes may discriminate between the cancerous and the normal cells. Here, we reported the investigation on the pro-apoptotic effect and the underlying mechanism of b...

journal_title：Journal of inorganic biochemistry

authors： Zhang Y,Wang L,Zeng K,Wang K,Yang X

更新日期：2018-11-01 00:00:00

abstract：:Industrial applications and environmental problems involving the aqueous chemistry of aluminium require an understanding of the speciation of this metal ion at a wide range of concentrations. The formation of polynuclear species is of special interest due to the complexity of the hydrolysis mechanisms and the diversit...

journal_title：Journal of inorganic biochemistry

authors： Perry CC,Shafran KL

更新日期：2001-11-01 00:00:00