Does myocardial stunning contribute to infarct size limitation by ischemic preconditioning?

abstract：BACKGROUND:The electrocardiographic short QT-interval syndrome forms a distinct clinical entity presenting with a high rate of sudden death and exceptionally short QT intervals. The disorder has recently been linked to gain-of-function mutation in KCNH2. The present study demonstrates that this disorder is genetically ...

journal_title：Circulation

authors： Bellocq C,van Ginneken AC,Bezzina CR,Alders M,Escande D,Mannens MM,Baró I,Wilde AA

更新日期：2004-05-25 00:00:00

abstract：:To elucidate the mechanism of regional hemostasis in the left ventricular (LV) cavity during myocardial infarction, the blood pathway in LV cavity was examined with contrast echocardiography injected from the left atrium before and after coronary ligation in nine canines. Before coronary ligation, contrast echoes spre...

journal_title：Circulation

authors： Beppu S,Izumi S,Miyatake K,Nagata S,Park YD,Sakakibara H,Nimura Y

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Pulmonary regurgitation frequently occurs after surgical correction of tetralogy of Fallot. To date, reliable quantitation of pulmonary regurgitation has not been possible, and therefore the clinical significance of pulmonary regurgitation is controversial. Nuclear magnetic resonance (NMR) velocity mapping a...

journal_title：Circulation

authors： Rebergen SA,Chin JG,Ottenkamp J,van der Wall EE,de Roos A

更新日期：1993-11-01 00:00:00

abstract：:Direct examination of the aortic orifice at the level of the aortic valves (aortic valvular orifice area, AVOA) in the short-axis plane was performed with a 3 MHz two-dimensional pulsed Doppler echocardiographic apparatus. The AVOA was mapped with the Doppler gate to detect or rule out the presence of a regurgitant ao...

journal_title：Circulation

authors： Veyrat C,Lessana A,Abitbol G,Ameur A,Benaim R,Kalmanson D

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:Clinical detection of transplant rejection by repeated endomyocardial biopsy requires catheterization and entails risks. Recently developed molecular and cellular imaging techniques that visualize macrophage host responses could provide a noninvasive alternative. Yet, which macrophage functions may provide u...

journal_title：Circulation

authors： Christen T,Nahrendorf M,Wildgruber M,Swirski FK,Aikawa E,Waterman P,Shimizu K,Weissleder R,Libby P

更新日期：2009-04-14 00:00:00

abstract：BACKGROUND:Whether cardiac rehabilitation (CR) is effective in patients older than 75 years, who have been excluded from most trials, remains unclear. We enrolled patients 46 to 86 years old in a randomized trial and assessed the effects of 2 months of post-myocardial infarction (MI) CR on total work capacity (TWC, in ...

journal_title：Circulation

authors： Marchionni N,Fattirolli F,Fumagalli S,Oldridge N,Del Lungo F,Morosi L,Burgisser C,Masotti G

更新日期：2003-05-06 00:00:00

abstract：BACKGROUND:Coronary perfusion pressure has been shown to be a significant determinant of return of spontaneous circulation from cardiac arrest during asystole and electromechanical dissociation. The addition of interposed abdominal compression to otherwise standard cardiopulmonary resuscitation (CPR) increases coronary...

journal_title：Circulation

authors： Sack JB,Kesselbrenner MB,Jarrad A

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:MRI of specific components in atherosclerotic plaque may provide information on plaque stability and its potential to rupture. We evaluated gadofluorine in atherosclerotic rabbits using a new MR sequence that allows plaque detection within 1 hour after injection and assessed enhancement in lipid-rich and non...

journal_title：Circulation

authors： Sirol M,Itskovich VV,Mani V,Aguinaldo JG,Fallon JT,Misselwitz B,Weinmann HJ,Fuster V,Toussaint JF,Fayad ZA

更新日期：2004-06-15 00:00:00

abstract：:In 58 patients with uncomplicated acute anterior myocardial infarction, a mean decline in the sum of ST segments (sigmaST) of 34% was observed when comparing sigmaST values recorded at 3-6 hours with those recorded at 6-9 hours after the onset of symptoms (P less than 0.05). The mean absolute difference between 19 pai...

journal_title：Circulation

authors： Hardarson T,Henning H,O'Rourke RA,Karliner JS,Ryan W,Ross J Jr

更新日期：1978-06-01 00:00:00

abstract：BACKGROUND:Exercise echocardiography (digital cine-loop technique) and 201Tl single-photon emission computed tomography (SPECT) were performed simultaneously in 292 patients being evaluated for coronary artery disease. METHODS AND RESULTS:Pretreadmill and posttreadmill echocardiographic images of diagnostic quality we...

journal_title：Circulation

authors： Quiñones MA,Verani MS,Haichin RM,Mahmarian JJ,Suarez J,Zoghbi WA

更新日期：1992-03-01 00:00:00

abstract：:This study analyzes the response to overdrive suppression of junctional pacemakers (JP) and correlates it with symptoms in 21 patients. Junctional rhythm (JR) was seen in 5 patients with intact A-V conduction, and in 16 with complete heart block, the JPs were located proximal to or within the His bundle (BH). Junction...

journal_title：Circulation

authors： Narula OS,Narula JT

更新日期：1978-05-01 00:00:00

abstract：BACKGROUND:National and international guidelines recommend fasting lipid panel measurement for risk stratification of patients for prevention of cardiovascular events. However, the prognostic value of fasting versus nonfasting low-density lipoprotein cholesterol (LDL-C) is uncertain. METHODS AND RESULTS:Patients enrol...

journal_title：Circulation

authors： Doran B,Guo Y,Xu J,Weintraub H,Mora S,Maron DJ,Bangalore S

更新日期：2014-08-12 00:00:00

abstract：BACKGROUND:The recent breakthrough in the generation of induced pluripotent stem (iPS) cells, which are almost indistinguishable from embryonic stem (ES) cells, facilitates the generation of murine disease- and human patient-specific stem cell lines. The aim of this study was to characterize the cardiac differentiation...

journal_title：Circulation

authors： Mauritz C,Schwanke K,Reppel M,Neef S,Katsirntaki K,Maier LS,Nguemo F,Menke S,Haustein M,Hescheler J,Hasenfuss G,Martin U

更新日期：2008-07-29 00:00:00

abstract：BACKGROUND:Pulmonary hypertension (PH) is a life-threatening disease. Bone marrow cell transplantation is reported to reduce the development of PH by increasing vascular beds in pulmonary circulation. However, adenoviral overexpression of endothelial nitric oxide synthase (eNOS) in the lung is also known to reduce PH. ...

journal_title：Circulation

authors： Kanki-Horimoto S,Horimoto H,Mieno S,Kishida K,Watanabe F,Furuya E,Katsumata T

更新日期：2006-07-04 00:00:00

abstract：BACKGROUND:Intentional weight loss is associated with lower risk of heart failure (HF) and atherosclerotic cardiovascular disease among patients with type 2 diabetes. However, the contribution of baseline measures and longitudinal changes in fat mass (FM), lean mass (LM), and waist circumference (WC) to the risk of HF ...

journal_title：Circulation

authors： Patel KV,Bahnson JL,Gaussoin SA,Johnson KC,Pi-Sunyer X,White U,Olson KL,Bertoni AG,Kitzman DW,Berry JD,Pandey A,Look AHEAD Research Group.

更新日期：2020-12-22 00:00:00

abstract：BACKGROUND:Long-term rapid atrial pacing may result in atrial fibrillation (AF) in dogs. Whether there is histological evidence for neural remodeling is unclear. METHOD AND RESULTS:We performed rapid right atrial pacing in 6 dogs for 111+/-76 days to induce sustained AF. Tissues from 6 healthy dogs were used as contro...

journal_title：Circulation

authors： Chang CM,Wu TJ,Zhou S,Doshi RN,Lee MH,Ohara T,Fishbein MC,Karagueuzian HS,Chen PS,Chen LS

更新日期：2001-01-02 00:00:00

abstract：:Nine patients with severe mitral disease were studied before and six months after mitral valve replacement with a three-cusp stented prosthesis using fresh autologous fascia lata tissue. Only patients in whom there was no auscultatory and angiographic evidence of incompetence of the replaced valve were selected for re...

journal_title：Circulation

authors： Taylor SH,Galvin MC,Pakrashi BC,Tulpule AT,Ionescu MI,Whitaker W

更新日期：1975-11-01 00:00:00

abstract：:Exercise trials in cardiology are often hindered by inconsistent approaches to exercise testing. These inconsistencies include the choice of exercise protocol, exercise end points, points of analysis, and absence or misuse of gas exchange data. Gas exchange techniques greatly enhance the accuracy with which cardiopulm...

journal_title：Circulation

authors： Myers J,Froelicher VF

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Macrophage migration inhibitory factor (MIF), a cytokine that controls cell-mediated inflammatory responses, is upregulated in atherogenesis; however, its functional contribution to lesion development has not been evaluated. METHODS AND RESULTS:We studied the role of MIF on neointima lesion formation after ...

journal_title：Circulation

authors： Schober A,Bernhagen J,Thiele M,Zeiffer U,Knarren S,Roller M,Bucala R,Weber C

更新日期：2004-01-27 00:00:00

abstract：BACKGROUND:Two types of ischemia, pacing-induced and coronary occlusion-induced, have different effects on left ventricular diastolic properties. During pacing-induced ischemia, the diastolic pressure-volume relation is said to shift upward, whereas during coronary occlusion, it is said to shift rightward or downward. ...

journal_title：Circulation

authors： Takano H,Glantz SA

更新日期：1995-05-01 00:00:00

abstract：:Four revolutions are transforming the cardiology of our day. The first is a social revolution. It has resulted in plummeting esteem for the medical profession reflecting disenchantment coupled with the rapid emergence of the recognition that health care is a right rather than a privilege. The second revolution, interv...

journal_title：Circulation

authors： Sobel BE

更新日期：1993-06-01 00:00:00

abstract：:Skeletal muscle ventricles were constructed from the latissimus dorsi in seven dogs. All skeletal muscle ventricles underwent a vascular delay period followed by 4-7 weeks of electrical preconditioning. In group 1 (n = 5), the skeletal muscle ventricle was used to replace native right-heart function. Venous return fro...

journal_title：Circulation

authors： Bridges CR Jr,Hammond RL,Dimeo F,Anderson WA,Stephenson LW

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:We identified a gene (PRKAG2) that encodes the gamma-2 regulatory subunit of AMP-activated protein kinase (AMPK) with a mutation (Arg302Gln) responsible for familial Wolff-Parkinson-White (WPW) syndrome. The human phenotype consists of ventricular preexcitation, conduction abnormalities, and cardiac hypertro...

journal_title：Circulation

authors： Sidhu JS,Rajawat YS,Rami TG,Gollob MH,Wang Z,Yuan R,Marian AJ,DeMayo FJ,Weilbacher D,Taffet GE,Davies JK,Carling D,Khoury DS,Roberts R

更新日期：2005-01-04 00:00:00

abstract：BACKGROUND:Although the use of physical signs for the diagnosis of ventricular tachycardia (VT) was described in the early 1900s, their value in this role has never been systematically assessed. METHODS AND RESULTS:Using a blinded, randomized protocol, we examined the ability of 26 clinicians to detect ventriculoatria...

journal_title：Circulation

authors： Garratt CJ,Griffith MJ,Young G,Curzen N,Brecker S,Rickards AF,Camm AJ

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Despite early recanalization of an occluded infarct artery, reperfusion at the level of the microcirculation may remain impaired owing to a process of microvascular reperfusion injury. METHODS AND RESULTS:Microvascular reperfusion injury was studied in 91 patients with acute myocardial infarction (AMI) by e...

journal_title：Circulation

authors： Claeys MJ,Bosmans J,Veenstra L,Jorens P,De RaedtH,Vrints CJ

更新日期：1999-04-20 00:00:00

abstract：BACKGROUND:C-reactive protein (CRP) and interleukin (IL)-6 are important risk factors for atherosclerosis and coronary heart disease. In the present study, we examined serum levels of CRP and IL-6, IL-6 production by monocytes, and the effect of nasal continuous positive airway pressure (nCPAP) in patients with obstruc...

journal_title：Circulation

authors： Yokoe T,Minoguchi K,Matsuo H,Oda N,Minoguchi H,Yoshino G,Hirano T,Adachi M

更新日期：2003-03-04 00:00:00

abstract：BACKGROUND:Temporal trends regarding the epidemiology of atherosclerotic renovascular disease (ARVD) in dialysis populations are poorly defined. METHODS AND RESULTS:United States Renal Data System data were used to identify patients aged 67 years or older at dialysis inception between 1996 and 2001 (n=146,973). Medica...

journal_title：Circulation

authors： Guo H,Kalra PA,Gilbertson DT,Liu J,Chen SC,Collins AJ,Foley RN

更新日期：2007-01-02 00:00:00

abstract：:The pericardium, because of the nature of its pressure-volume relation, can influence left ventricular diastolic and systolic pump function. During an acute increase in heart size that results in the stretching of the pericardium, the elastic properties of the pericardium restrict further cardiac dilatation and curtai...

journal_title：Circulation

authors： Janicki JS

更新日期：1990-02-01 00:00:00

abstract：:Twenty-six patients with unstable angina pectoris had biplane left ventricular (LV) angiograms and coronary arteriograms (CAGs) initially and at a median of 1 year following randomization to medical (15 patients) or surgical 11 patients) therapy. Left ventricular segmental wall motion was analyzed by a digital compute...

journal_title：Circulation

authors： Priest MF,Curry GC,Smith LR,Rogers WJ,Mantle JA,Rackley CE,Kouchoukos NT,Russell RO Jr

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:Whether the benefit in quality of life (QOL) after percutaneous coronary intervention depends on the severity of the stenosis as determined by fractional flow reserve (FFR) remains unknown. This study sought to investigate the relationship between FFR values and improvement in QOL. METHODS:From the FAME 1 a...

journal_title：Circulation

authors： Nishi T,Piroth Z,De Bruyne B,Jagic N,Möbius-Winkler S,Kobayashi Y,Derimay F,Fournier S,Barbato E,Tonino P,Jüni P,Pijls NHJ,Fearon WF

更新日期：2018-10-23 00:00:00