In vivo induction of HLA molecules in patients with myeloproliferative syndrome during IFN alpha treatment.

abstract：:We evaluated the clinical features, treatment modalities, treatment responses, and prognosis of our patients with immune thrombocytopenia (ITP). Furthermore, we estimated the frequency of ITP in the Thrace region of Turkey. Two hundred sixteen patients diagnosed with ITP between 2000 and 2012 at our center were retros...

journal_title：Annals of hematology

authors： Koylu A,Pamuk GE,Uyanik MS,Demir M,Pamuk ON

更新日期：2015-03-01 00:00:00

abstract：:Symptomatic multiple myeloma (MM) is a plasma cell neoplasm that represents the final stage of a continuum of clinical conditions that start from monoclonal gammopathy of unknown significance (MGUS), then transits in the more advance, but still asymptomatic, smoldering MM (SMM), with a final evolution in symptomatic M...

journal_title：Annals of hematology

authors： Mussetti A,Pellegrinelli A,Cieri N,Garzone G,Dominoni F,Cabras A,Montefusco V

更新日期：2019-07-01 00:00:00

abstract：:Acute leukemia (AL) patients may experience more than one episode of bloodstream infection (BSI) caused by the same pathogen during the entire chemotherapy program. In order to identify factors influencing BSI recurrence (R-BSI) during subsequent phases of treatment, we analyzed all BSIs occurring to consecutively tre...

journal_title：Annals of hematology

authors： Cattaneo C,Antoniazzi F,Tumbarello M,Skert C,Borlenghi E,Schieppati F,Cerqui E,Pagani C,Petullà M,Re A,Rossi G

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Low folate intake and changes in folate metabolism due to polymorphisms in the methylentetrahydrofolate reductase (MTHFR) gene have been associated with myelomagenesis. However, controversial data have been published regarding a protective role of variant alleles of MTHFR on MM. PATIENTS AND METHODS:To inve...

journal_title：Annals of hematology

authors： Chiusolo P,Farina G,Putzulu R,Reddiconto G,Fiorini A,De Stefano V,Rossi E,Palladino M,Leone G,Sica S

更新日期：2006-07-01 00:00:00

abstract：:Multiple myeloma is a malignant B-cell neoplasm that involves the skeleton in approximately 80% of the patients. With an average age of 60 years and a 5-years survival of nearly 45% Brenner et al. (Blood 111:2516-2520,35) the onset is to be classified as occurring still early in life while the disease can be very aggr...

journal_title：Annals of hematology

authors： Lütje S,de Rooy JW,Croockewit S,Koedam E,Oyen WJ,Raymakers RA

更新日期：2009-12-01 00:00:00

abstract：:This retrospective single-center study compared thromboembolic and hemorrhagic complications, survival and causes of death in a cohort of 102 consecutive patients with myeloproliferative disorders (MPD). We included 17 patients with essential thrombocythemia (ET), 59 with polycythemia vera (PV), and 26 with osteomyelo...

journal_title：Annals of hematology

authors： Brodmann S,Passweg JR,Gratwohl A,Tichelli A,Skoda RC

更新日期：2000-06-01 00:00:00

abstract：:We have studied the effects of recombinant human thrombopoietin (TPO, mpl ligand) on the megakaryocyte colony formation from control human bone marrow cells, human leukemia cells at diagnosis, and human bone marrow cells after induction chemotherapy for acute leukemias. In the control human bone marrow cells from four...

journal_title：Annals of hematology

authors： Liang DC,Shih LY,Kuo MC,Chen SH,Liu HC,Shimosaka A

更新日期：1998-07-01 00:00:00

abstract：:Five major subtypes of human T-lymphotropic virus type I (HTLV-I) have been proposed: cosmopolitan, Japanese, West African, Central African, and Melanesian. Based on nucleotide variations specific to particular subtypes, it was possible to genotype HTLV-I rapidly by restriction fragment length polymorphism (RFLP) stud...

journal_title：Annals of hematology

authors： Lin MT,Yang YC,Chen PJ,Tang JI,Tseng LH,Wang CW,Chen YC

更新日期：1996-09-01 00:00:00

abstract：:High-dose immunosuppressive therapy (HDIT) with autologous hematopoietic stem cell transplantation (AHSCT) is a promising approach to treatment of multiple sclerosis (MS) patients. In this paper, we present the long-term outcomes of a prospective single-center study with the analysis of the safety and efficacy of HDIT...

journal_title：Annals of hematology

authors： Shevchenko JL,Kuznetsov AN,Ionova TI,Melnichenko VY,Fedorenko DA,Kurbatova KA,Gorodokin GI,Novik AA

更新日期：2015-07-01 00:00:00

abstract：:We investigated the efficacy of an antithymocyte globulin/cyclophosphamide preparative regimen prior to allogeneic stem cell transplantation from HLA-identical siblings in patients with severe aplastic anemia. Since 1990, 21 patients, 6 males and 15 females, with a median age of 25 years (range: 7-43) have been enroll...

journal_title：Annals of hematology

authors： Kröger N,Zabelina T,Renges H,Krüger W,Kordes U,Rischewski J,Schrum J,Horstmann M,Ayuk F,Erttmann R,Kabisch H,Zander AR

更新日期：2002-11-01 00:00:00

abstract：:The purpose of this cross-sectional prospective study was to determine the prevalence of anemia among elderly hospitalized patients in Germany and to investigate its association with multidimensional loss of function (MLF). One hundred participants aged 70 years or older from two distinct wards (50 each from an emerge...

journal_title：Annals of hematology

authors： Zilinski J,Zillmann R,Becker I,Benzing T,Schulz RJ,Roehrig G

更新日期：2014-10-01 00:00:00

abstract：:There is little information about cardiovascular adverse event (CV-AE) incidence in chronic myeloid leukemia (CML) patients treated with bosutinib in the real-life practice. We identified 54 consecutive CML patients treated with bosutinib, stratified according to the Systematic Coronary Risk Evaluation (SCORE) assessm...

journal_title：Annals of hematology

authors： Caocci G,Mulas O,Abruzzese E,Iurlo A,Annunziata M,Orlandi EM,Galimberti S,Binotto G,Sgherza N,Luciano L,Martino B,Russo Rossi A,Bonifacio M,Fozza C,Trawinska MM,Cattaneo D,Elena C,Baratè C,De Gregorio F,Molica M,L

更新日期：2019-08-01 00:00:00

abstract：:The present paper summarizes the results of the second German consensus meeting on immunogenetic donor search for allotransplantation of hematopoietic stem cells held in Essen in November 1999 under the auspices of the German Society for Immunogenetics (DGI) and the German Working Party for Blood and Marrow Transplant...

journal_title：Annals of hematology

authors： Ottinger HD,Müller CR,Goldmann SF,Albert E,Arnold R,Beelen DW,Blasczyk R,Bunjes D,Casper J,Ebell W,Ehninger G,Eiermann T,Einsele H,Fauser A,Ferencik S,Finke J,Hertenstein B,Heyll A,Klingebiel T,Knipper A,Kremens B

更新日期：2001-12-01 00:00:00

abstract：:Several revisions of International Prognostic Index (IPI) have been proposed for patients with diffuse large B-cell lymphoma (DLBCL) after the introduction of rituximab. Expanding evidence suggests that baseline absolute lymphocyte count (ALC) is also an independent factor for outcome prediction. We investigated the o...

journal_title：Annals of hematology

authors： Huang YC,Liu CY,Lu HJ,Liu HT,Hung MH,Hong YC,Hsiao LT,Gau JP,Liu JH,Hsu HC,Chiou TJ,Chen PM,Tzeng CH,Yu YB

更新日期：2013-11-01 00:00:00

abstract：:The most common causes of morbidity and mortality in myeloproliferative neoplasms (MPN) are thrombotic and hemorrhagic complications. The JAK2V617F mutation, commonly found in MPN, correlates with several clinical and laboratory characteristics even if the relevance of JAK2V617F allele burden in the natural history of...

journal_title：Annals of hematology

authors： Bertozzi I,Bogoni G,Biagetti G,Duner E,Lombardi AM,Fabris F,Randi ML

更新日期：2017-08-01 00:00:00

abstract：:Idarubicin belongs to a group of anthracyclines in which the methoxyl group in position 4 of the D ring in the aglycone moiety is replaced by a hydrogen atom. Lipophilicity is increased compared with other anthracyclines; as a result, idarubicin is the first anthracycline that can be administered orally while at the s...

journal_title：Annals of hematology

authors： Goebel M

更新日期：1993-01-01 00:00:00

abstract：:Extramedullary (e) relapse in multiple myeloma(MM) has an adverse prognosis, but knowledge concerning biological features and preferred treatment is scarce. We screened the myeloma registry of our institution for eMM relapses and identified 24 cases among 357 patients (pts).Only 8% of eMM relapses occurred after initi...

journal_title：Annals of hematology

authors： Rasche L,Bernard C,Topp MS,Kapp M,Duell J,Wesemeier C,Haralambieva E,Maeder U,Einsele H,Knop S

更新日期：2012-07-01 00:00:00

abstract：:We conducted a phase 2 study with bortezomib, doxorubicin, and dexamethasone (PAD) followed by thalidomide and dexamethasone (TD) in patients with relapsed multiple myeloma (MM). Forty patients were enrolled between November 2005 and October 2007, with follow-up continuing until January 2009. Efficacy could be assesse...

journal_title：Annals of hematology

authors： Lee SS,Suh C,Kim BS,Chung J,Joo YD,Ryoo HM,Do YR,Jin JY,Kang HJ,Lee GW,Lee MH,Shim H,Kim K,Yoon SS,Bang SM,Kim HY,Lee JJ,Park J,Lee DS,Lee JH,Korean Multiple Myeloma Working Party.

更新日期：2010-09-01 00:00:00

abstract：:In the attempt to induce graft-vs-host disease (GVHD) in patients undergoing autologous bone marrow transplantation (ABMT) or blood stem cell transplantation (BSCT), 12 consecutive patients received cyclosporin A (CyA) post transplant. CyA was given at a dose of 1.5 mg/kg/day intravenously for 28 days, starting on the...

journal_title：Annals of hematology

authors： Carella AM,Gaozza E,Congiu A,Carlier P,Nati S,Truini M,Castellaneta A,Viale M

更新日期：1991-05-01 00:00:00

abstract：:Cerebral involvement is an unusual complication in multiple myeloma: herein four patients who presented myelomatous meningitis with multiple intraparenchymal lesions or a localized cerebral plasmacytoma are described. Two of these patients relapsed with meningeal involvement and a very limited disease outside the cent...

journal_title：Annals of hematology

authors： Patriarca F,Zaja F,Silvestri F,Sperotto A,Scalise A,Gigli G,Fanin R

更新日期：2001-12-01 00:00:00

abstract：:We have performed a retrospective analysis of all patients with extragastric mucosa-associated lymphoid tissue (MALT) lymphoma treated at our institution to compare the efficacy of first-line therapeutic modalities including surgery, radiation, systemic therapy, and antibiotics. One hundred eighty-five patients with e...

journal_title：Annals of hematology

authors： Wöhrer S,Kiesewetter B,Fischbach J,Müllauer L,Troch M,Lukas J,Mayerhoefer ME,Raderer M

更新日期：2014-08-01 00:00:00

abstract：:We retrospectively evaluated the role of rituximab (R) in maintenance treatment after autologous stem cell transplantation performed in patients with relapsed follicular lymphoma. We compared the outcome of 67 follicular lymphoma (FL) patients according to the use of rituximab maintenance (RM) or not. All patients rec...

journal_title：Annals of hematology

authors： Bourcier J,Gastinne T,Leux C,Moreau A,Bossard C,Mahé B,Blin N,Dubruille V,Touzeau C,Voldoire M,Guillaume T,Peterlin P,Gallas P,Garnier A,Maisonneuve H,Moreau P,Juge-Morineau N,Jardel H,Chevallier P,Moreau P,Le Gou

更新日期：2016-08-01 00:00:00

abstract：:High-dose chemotherapy with autologous peripheral blood stem cell transplantation (PBSCT) includes the risk of infectious complications due to neutropenia and therapy-induced immune deviation. In order to understand early immune recovery in this situation, we analyzed the distribution of cell subsets by flow cytometry...

journal_title：Annals of hematology

authors： Krause SW,Rothe G,Gnad M,Reichle A,Andreesen R

更新日期：2003-10-01 00:00:00

abstract：:Less toxic and more active treatments are needed for indolent lymphomas as there is no curative treatment, and patients eventually die due to complications related to their disease. The purpose of the present study was to assess the antitumour activity of the combination of low doses of Enzastaurin and Lenalidomide (R...

journal_title：Annals of hematology

authors： Cosenza M,Civallero M,Grisendi G,Marcheselli L,Roat E,Bari A,Sacchi S

更新日期：2012-10-01 00:00:00

abstract：:The production of erythropoietin (Epo), the glycoprotein hormone which controls red blood cell formation, is regulated by feedback mechanisms sensing tissue oxygenation. The mechanism of the putative oxygen sensor has yet to be elucidated. There is evidence that at least two pathways participate in hypoxia signal tran...

journal_title：Annals of hematology

authors： Daghman NA,Elder GE,Savage GA,Winter PC,Maxwell AP,Lappin TR

更新日期：1999-06-01 00:00:00

abstract：:The general objective of this study was to evaluate the risks of agranulocytosis and aplastic anemia in relation to drug use. Other potential risk factors, including history of infectious mononucleosis, were also evaluated. In an international population-based case-control study, cases of agranulocytosis and aplastic ...

journal_title：Annals of hematology

authors： Levy M,Kelly JP,Kaufman DW,Shapiro S

更新日期：1993-10-01 00:00:00

abstract：:Cells of the macrophage lineage are a major source of various cytokines and hematopoietic growth factors. With regard to the growth factors acting on cells of their own lineage, macrophage colony-stimulating factor (M-CSF) has been proven to be secreted by monocytes (MO) and macrophages (MAC), whereas the production o...

journal_title：Annals of hematology

authors： Krause SW,Kreutz M,Zenke G,Andreesen R

更新日期：1992-04-01 00:00:00

abstract：:Recently we described a cutaneous T-cell lymphoma expressing the gamma/delta T-cell receptor [5]. The patient suffering from this lymphoma showed low numbers of myeloid and T cells in peripheral blood, while B and NK cells were relatively increased. In vitro culture of the patient's bone marrow (BM) cells revealed a s...

journal_title：Annals of hematology

authors： Wilhelm M,Meyer P,Batram C,Tony HP,Dummer R,Nestle F,Burg G,Wilms K

更新日期：1992-09-01 00:00:00

abstract：:Hodgkin lymphoma (HL) in resource-poor population shows an early childhood peak with predominance of mixed cellularity (MCHL) and high Epstein-Barr virus (EBV) association, whereas HL in resource-rich population has a peak in ages 15-29 years with the predominance of nodular sclerosis (NSHL) and low EBV association. W...

journal_title：Annals of hematology

authors： Koh YW,Kang HJ,Yoon DH,Suh C,Kim JE,Kim CW,Huh J

更新日期：2013-12-01 00:00:00

abstract：:We report a factor X (FX)-deficient Chinese family with two novel FX gene (F10) mutations. Two sibling probands had a bleeding tendency since childhood. Both had very low FX:C (<0.01 IU/ml) and FX:Ag (5-6%) levels and were heterozygous for two novel F10 mutations, a 2-bp GC deletion involving nucleotides 33 and 34, le...

journal_title：Annals of hematology

authors： Au WY,Lam CC,Cheung WC,Kwong YL

更新日期：2004-05-01 00:00:00