Abstract:
OBJECTIVE:To assess cerebral blood flow (CBF) changes in patients with mild traumatic brain injury (MTBI) using an arterial spin labelling (ASL) perfusion MRI and to investigate the severity of neuropsychological functional impairment with respect to haemodynamic changes. MATERIALS AND METHODS:Twenty-one patients with MTBI and 20 healthy controls were studied at 3T MR. The median time since the onset of brain injury in patients was 24.6 months. Both patients and controls underwent a traditional consensus battery of neurocognitive tests. ASL was performed using true fast imaging with steady state precession and a flow-sensitive alternating inversion recovery preparation. Regional CBF were measured in both deep and cortical gray matter as well as white matter at the level of basal ganglia. RESULTS:The mean regional CBF was significantly lower in patients with MTBI (45.9 +/- 9.8 ml/100 g min(-1)) as compared to normal controls (57.1 +/- 8.1 ml/100 g min(-1); p = 0.002) in both sides of thalamus. The decrease of thalamic CBF was significantly correlated with several neurocognitive measures including processing and response speed, memory/learning, verbal fluency and executive function in patients. CONCLUSIONS:Haemodynamic impairment can occur and persist in patients with MTBI, the extent of which is more severe in thalamic regions and correlate with neurocognitive dysfunction during the extended course of disease.
journal_name
Brain Injjournal_title
Brain injuryauthors
Ge Y,Patel MB,Chen Q,Grossman EJ,Zhang K,Miles L,Babb JS,Reaume J,Grossman RIdoi
10.1080/02699050903014899subject
Has Abstractpub_date
2009-07-01 00:00:00pages
666-74issue
7eissn
0269-9052issn
1362-301Xpii
912685630journal_volume
23pub_type
杂志文章相关文献
BRAIN INJURY文献大全abstract::The use of linear measurements in the analysis of CT scans of TBI patients was found to contribute to the understanding of brain damage and were correlated with outcome in severe traumatic close brain injured patients. The purpose of the present study was to analyse the data obtained by the linear measurements on CT s...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/026990597122936
更新日期:1997-12-01 00:00:00
abstract::Primary Objective: Survey TBI literature to identify evidence of risk for post-injury suicide. Literature Selection: Search terms ((traumatic brain injury OR TBI) AND (suicidality OR suicidal behaviour OR suicidal ideation)) entered in PubMed, OVID Medline, PsychInfo, and Web of Science for papers published in print 0...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699052.2020.1861656
更新日期:2021-01-18 00:00:00
abstract::The aim of this case report is to describe the time course of S-100 serum levels of a patient, after severe head injury, whose blood sample could be drawn very soon after injury. The results were compared to a group of patients in which a correlation between S-100 serum levels and outcome after traumatic brain injury ...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/026990599121584
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVE:To investigate the relationship between working alliance, compliance, awareness and subjective outcome of brain injury rehabilitation. Subjects were 86 patients who were clients in an holistic neuropsychological outpatient rehabilitation programme. They had suffered a traumatic brain injury (n = 27), a cerebr...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699050601049395
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:In work with chronic stroke patients the authors observed that patients frequently appear sleepy and often comment on their poor sleep. Sleep difficulties are frequently reported and indeed clinically recognized in the acute phase post-stroke, but little is known about the sleep and daytime sleep...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699050802189727
更新日期:2008-07-01 00:00:00
abstract::Constructional apraxia was evaluated in patients with aphasia using a cube-copying task. It was assessed whether quantitative assessment of cube copying could be used to estimate the performance intelligence quotient (IQ) according to neuropsychological tests. Abnormality in the cube-copying test was observed in 42 of...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699050110102095
更新日期:2002-02-01 00:00:00
abstract::This case history describes the successful use of a commercially available memory book by a brain injury survivor, including a description of the characteristics which made the book acceptable. Implications of the normalization principle for memory rehabilitation are also discussed. ...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699059309008160
更新日期:1993-01-01 00:00:00
abstract:PRIMARY OBJECTIVE:Balance disturbances occur in ∼30% of concussion injuries, with vestibular dysfunction reported as the main contributor. However, few have studied oculomotor control post-concussion to assess vestibular dysfunction. RESEARCH DESIGN:The current research measured the differences in oculomotor control b...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699052.2014.887144
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:A study was initiated with the intent of demonstrating the cumulative effects of concussion in junior hockey players using visual event-related potentials and post-concussion syndrome (PCS) self-reports. METHODS:Players were assessed at the beginning of the season (pre-injury) and at various times post-injury....
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699050050203577
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVE:To study the effects on the hemiplegic upper limb of repetitive facilitation exercises (RFEs) using a novel facilitation technique, in which the patient's intention to move the hemiplegic upper limb or finger was followed by realization of the movement using multiple sensory stimulations. METHODS:Twenty-thre...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699052.2010.506855
更新日期:2010-01-01 00:00:00
abstract:AIM:To evaluate the management and guideline adherence in children with mild traumatic brain injury (MTBI) in emergency departments (ED) in the Netherlands. METHODS:A multicentre cohort study was conducted, including children younger than 18 years with MTBI who presented within 24 hours after trauma in the ED of hospi...
journal_title:Brain injury
pub_type: 杂志文章,多中心研究
doi:10.1080/02699052.2018.1469047
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:There is limited research on communicative recovery during the early stages after a severe traumatic brain injury (TBI) in adults. METHODS AND PROCEDURES:In the current study 43 people with severe TBI described a simple procedure at 3 and 6 months post injury and this was compared to the description provide...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699052.2017.1291989
更新日期:2018-01-01 00:00:00
abstract:AIM:To examine characteristics associated with physical activity capacity and performance in children with acquired brain injury (ABI). METHODS:58 children (32 men; age 11 years 11 months ± 2 years 6 months; Gross motor function classification system [GMFCS] equivalent I = 29, II = 29) >12 months post ABI were recruit...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699052.2017.1291990
更新日期:2017-01-01 00:00:00
abstract::This study examines the frequency of traumatic brain injury (TBI) in an HIV/AIDS population and its associated symptomatology. A panel of 173 individuals with HIV were split into two groups--those who have experienced a blow to the head within their lifetime (n = 128) and those who have not (n = 45). Self-reported sym...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/026990500120916
更新日期:2000-01-01 00:00:00
abstract:MAIN OBJECTIVE:Disorders of consciousness (DOC; encompassing coma, vegetative state/unresponsive wakefulness syndrome (VS/UWS) and minimally conscious state minus/plus (MCS-/+)) are associated with structural brain injury. The extent of this damage remains poorly understood and merits a detailed examination using novel...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699052.2015.1118765
更新日期:2016-01-01 00:00:00
abstract::In a simulated functional task involving comprehension of a spoken passage, the performance of 20 traumatically brain-injured and 14 non-brain-injured control patients was compared under conditions which included the presence and absence of competing vocal stimuli. The subjects heard 10 target paragraphs which were ap...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699058809150937
更新日期:1988-04-01 00:00:00
abstract::The term 'concussion' has been applied to head injuries of varying severity. Most studies have examined subjects suffering concussion of a severity requiring hospital observation, usually as a consequence of motor vehicle accidents. Milder concussive injuries such as those resulting from contact sport are often not re...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/026990596124584
更新日期:1996-02-01 00:00:00
abstract::Objective: To assess the concurrent validity and test re-test reliability of the Michigan Traumatic Brain Injury Identification Method (MTBIIM). The psychometric properties of this concussion index were investigated by comparing the agreement between player self-reported diagnosed concussions and medical record diagno...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699052.2020.1858160
更新日期:2020-12-31 00:00:00
abstract:PRIMARY OBJECTIVE:To revise the scaling of the response sets of the Acquired Brain Injury Challenge Assessment (ABI-CA) through expert input and determination of empirically based cut-points. RESEARCH DESIGN:A measurement development study with a content validity focus. METHODS:Response option wording was revised thr...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699052.2013.809551
更新日期:2013-01-01 00:00:00
abstract::We have reported a large study of patients admitted to hospital following head injury in the city of Glasgow over one calendar year. This showed 1000 patients still to be disabled one year after their injury. In order to see whether the difficulties reported by these patients represented needs for rehabilitation servi...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699050210154231
更新日期:2002-12-01 00:00:00
abstract::Patients with brain tumours often report distress. Interpretive problems ensue when measures normed on healthy persons are utilized to quantify distress. This study investigated potentially spurious elevations on the Hopkins Symptom Checklist 90 Revised (SCL 90-R). Responses of 17 patients were obtained prior to aggre...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/026990598122674
更新日期:1998-03-01 00:00:00
abstract:OBJECTIVE:To investigate longitudinal changes in cortical and subcortical volumes in patients with mild traumatic brain injury (MTBI) and to evaluate whether such changes were associated with self-reported post-concussive symptoms, global functional outcomes and neuropsychological functioning. METHODS:This was a prosp...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699052.2017.1283537
更新日期:2017-01-01 00:00:00
abstract::Biased responding on the Sternberg Recognition Memory Test was observed in four patients with traumatic brain injury. None of these individuals met the Diagnostic and Statistical Manual's (DSM-IV) criteria for malingering. Individual recognition memory scores were high shortly after injury, declined to chance or below...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699050010013671
更新日期:2001-08-01 00:00:00
abstract::The present study had two main objectives: Firstly, to document the economic differences between 'ordinary' and 'aggressive' neurosurgical intensive care and secondly, to evaluate the medical benefits in relation to costs for different subgroups of head-injured patients. The study compares patients injured in traffic ...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699058909029641
更新日期:1989-07-01 00:00:00
abstract::Neuropsychological outcome and recovery of a group of 91 patients with moderate-to-severe head injuries were prospectively investigated over a 2 year period, with evaluations at acute hospital discharge at 6 months and 2 years post-injury. A group of 39 trauma patients with injuries to parts of the body other than the...
journal_title:Brain injury
pub_type: 临床试验,杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:This study aimed to investigate the incidence and clinical characteristics of chronic subdural haematoma (CSDH) evolving from traumatic subdual hydroma (TSH). METHODS:The clinical characteristics of 44 patients with CSDH evolving from TSH were analysed retrospectively and the relevant literature was reviewed...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.3109/02699052.2014.990513
更新日期:2015-01-01 00:00:00
abstract:PRIMARY OBJECTIVE:To gather information about brain injury (BI) survivors' long-term healthcare needs, quality, barriers and facilitators. RESEARCH DESIGN:Qualitative content analysis of data gathered in focus groups using semi-structured interviews. METHODS:Forty-four community-dwelling adults participated at two cl...
journal_title:Brain injury
pub_type: 杂志文章,多中心研究
doi:10.1080/02699052.2018.1429024
更新日期:2018-01-01 00:00:00
abstract:AIM:The present study aimed to examine attentional deficits in patients with persisting post-concussive symptoms using a multi-componential framework of attention. DESIGN:A cross-sectional investigation using standardized tests and questionnaires of attention including 92 patients. METHOD:Participants were administer...
journal_title:Brain injury
pub_type: 杂志文章,多中心研究
doi:10.1080/0269905021000010168
更新日期:2003-02-01 00:00:00
abstract:OBJECTIVE:To explore the utility of Timed Digit Span (TDS) as an embedded performance validity test (PVT) in a sample of veterans with mild traumatic brain injury (mTBI). We hypothesize that TDS will predict PVT failure on an established stand-alone measure (Trial 1 of the Test of Memory Malingering; TOMM). METHODS:TD...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/02699052.2018.1553311
更新日期:2019-01-01 00:00:00
abstract::The Wechsler Adult Intelligence Scale-Revised (WAIS-R) Verbal IQ-Performance IQ (VIQ-PIQ) discrepancy and a number of indices of intersubtest scatter were examined in 25 subjects with a history of traumatic brain injury (TBI) and magnetic resonance imaging (MRI) evidence of structural brain abnormality. Abnormal VIQ-P...
journal_title:Brain injury
pub_type: 杂志文章
doi:10.1080/026990596124098
更新日期:1996-09-01 00:00:00