N400 responses of children with primary language disorder: intervention effects.

Abstract:

:Event-related brain potentials were examined in 6 to 8-year-old children with primary language disorder before and after a 5-week narrative-based language intervention. Participants listened to sentences ending with semantically congruous or incongruous words. By comparison with typical controls, the children with primary language disorder exhibited no pretreatment differences in their N400 responses to congruous and incongruous sentence-final words. After intervention, the typical incongruous-congruous difference was observable owing to a dramatic reduction in the amplitude of the N400 response to congruous words. These characteristic changes in brain responses may reflect a positive effect of the language intervention on the lexical-semantic processing skills in children with language impairment.

journal_name

Neuroreport

journal_title

Neuroreport

authors

Popescu M,Fey ME,Lewine JD,Finestack LH,Popescu EA

doi

10.1097/WNR.0b013e32832e9c97

subject

Has Abstract

pub_date

2009-08-05 00:00:00

pages

1104-8

issue

12

eissn

0959-4965

issn

1473-558X

journal_volume

20

pub_type

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