Mortality of patients with renal dysfunction after percutaneous coronary intervention.

Abstract:

AIM:To determine the impact of stages of renal dysfunction on mortality after percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS). PATIENTS AND METHODS:A total of 449 patients (mean age 63 +/- 11.9 years) with ACS after PCI were included. Serum creatinine was determined and creatinine clearance was calculated using the Modification of Diet in Renal Disease (MDRD) formula. RESULTS:The prevalence of chronic kidney disease (CKD) defined as glomerular filtration rate (GFR) <60 mL/min per 1.73 m(2) was 26.3%. After up to 787 days of follow-up, 40 patients had died. Kaplan-Meier survival analysis showed progressively higher risk for cardiovascular death from stage 1 to stage 4 of renal dysfunction. In an adjusted Cox model, gender (P < .009), age (P < .0001), total cholesterol level (P < .01), and stage of renal dysfunction (P < .04) were predictors of mortality. CONCLUSIONS:In patients with ACS after PCI, a higher stage of renal dysfunction was directly associated with higher mortality of these patients.

journal_name

Angiology

journal_title

Angiology

authors

Bevc S,Penko M,Kanic V,Hojs R

doi

10.1177/0003319709335511

subject

Has Abstract

pub_date

2010-02-01 00:00:00

pages

24-30

issue

1

eissn

0003-3197

issn

1940-1574

pii

0003319709335511

journal_volume

61

pub_type

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