Abstract:
OBJECTIVES:Anaesthetic management of pheochromocytoma is far from satisfactory even though various techniques are available. Feasibility as well as safety of Bi-spectral Index (BIS)-guided closed-loop control of anaesthesia has been shown in various clinical settings. We evaluated the performance of BIS-guided closed-loop-anaesthesia-delivery system (CLADS) in patients undergoing resection of pheochromocytoma. METHODS:Thirteen patients (7 males and 6 females, 15-65 years) who underwent adrenalectomy for pheochromocytoma in the past 4 years operated by a single surgeon were included in the study. Closed-loop-control of propofol-anaesthesia was induced and maintained with target BIS value =50. RESULTS:Median performance error and median absolute performance error of target BIS control were 2 (2-7) [median (IQR)] and 10 (8-10), respectively. BIS was maintained within 50 +/- 10 for 87 +/- 8.6% (mean +/- SD) of the valid CLAD time. Heart rate (HR) and mean arterial pressure (MAP) were maintained within +/-25% of the baseline value for 90.3 +/- 12.1% and 76.3 +/- 13.2% of the time duration, respectively. BIS increased significantly following intubation, incision and tumor handling (P = 0.001, 0.001 and 0.03 respectively). There was a significant fall in both HR and MAP following induction of anaesthesia (P = 0.001), and MAP following tumor excision (P = 0.045) as compared to the baseline. Though maximum HR within 5 min post-intubation, post-incision and during tumor handling were significantly higher (P = 0.001, 0.014 and 0.037) compared to just before the respective event, they were not statistically different from the baseline. Though maximum MAP within 5 min post-intubation, post-incision and during tumor handling were significantly higher compared to MAP just before the respective event (P = 0.001, 0.021 and 0.001), they were not significantly different compared to the baseline value except maximum MAP during tumor handling (P = 0.001). CONCLUSION:CLADS performed well in patients undergoing pheochromocytoma surgeries which represent one of the few clinically extreme situations.
journal_name
J Clin Monit Computjournal_title
Journal of clinical monitoring and computingauthors
Hegde HV,Puri GD,Kumar B,Behera Adoi
10.1007/s10877-009-9181-0subject
Has Abstractpub_date
2009-08-01 00:00:00pages
189-96issue
4eissn
1387-1307issn
1573-2614journal_volume
23pub_type
杂志文章abstract::We aimed at identifying a model that dynamically predicts future need for renal replacement therapy (RRT) in intensive care unit (ICU) patients and can easily be implemented for online monitoring at the bedside. 7290 interdisciplinary ICU admissions were investigated. Patients with <3 days of stay or RRT in the first ...
journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章
doi:10.1007/s10877-015-9814-4
更新日期:2017-02-01 00:00:00
abstract::Increasing process complexity in the pediatric intensive care unit (PICU) can lead to information overload resulting in missing pertinent information and potential errors during morning rounds. An efficient model using a novel electronic rounding tool was designed as part of a broader critical care decision support sy...
journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
pub_type: 临床试验,杂志文章
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journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章
doi:10.1007/s10877-005-9000-1
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journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章,评审
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章,多中心研究
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章
doi:10.1007/s10877-015-9708-5
更新日期:2015-10-01 00:00:00
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journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章
doi:10.1007/s10877-014-9551-0
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
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journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章
doi:10.1007/s10877-008-9144-x
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journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章
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journal_title:Journal of clinical monitoring and computing
pub_type: 社论
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journal_title:Journal of clinical monitoring and computing
pub_type: 杂志文章
doi:10.1023/a:1009990210114
更新日期:2000-01-01 00:00:00
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journal_title:Journal of clinical monitoring and computing
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