Successful prophylaxis with valaciclovir for relapsing HSV-1 in a girl treated with infliximab for moderate Crohn's disease.

Abstract:

:Biological agents such as inhibitors of tumour necrosis factor alpha (TNF-alpha ) are associated with the development of opportunistic infections. Although there are no international recommendations for the management of opportunistic infections, their prevention is a key safety issue for patients with inflammatory bowel disease (IBD). We report that chemoprophylaxis with oral valaciclovir was effective in preventing Herpes simplex virus (HSV-1) reactivation in a girl treated with infliximab for Crohn's disease.

authors

Checchin D,Buda A,Sgarabotto D,Sturniolo GC,D' Incà R

doi

10.1097/MEG.0b013e32831de271

subject

Has Abstract

pub_date

2009-09-01 00:00:00

pages

1095-6

issue

9

eissn

0954-691X

issn

1473-5687

journal_volume

21

pub_type

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