Fibrates in the treatment of cardiovascular risk and atherogenic dyslipidaemia.

abstract：PURPOSE OF REVIEW:Atrial fibrillation is an important cause of morbidity in the aging population. The mechanisms responsible for the triggering and maintenance of the chaotic atrial rhythm are still poorly understood. In this review, we will focus on the genetic aspects of atrial fibrillation, to understand causality, ...

journal_title：Current opinion in cardiology

authors： Pérez-Serra A,Campuzano O,Brugada R

更新日期：2017-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide a broad overview of the current state of knowledge of coronary artery bypass grafting with bilateral internal thoracic artery (BITA). RECENT FINDINGS:There exists a large body of literature from mostly observational studies supporting the use of BITA in patients undergoing coronary artery ...

journal_title：Current opinion in cardiology

authors： Yanagawa B,Verma S,Puskas JD

更新日期：2017-09-01 00:00:00

abstract：:Assessment of the pulmonary circulation and right ventricular function is a cornerstone in the evaluation of the patient as a potential heart transplant recipient. The importance of pulmonary hypertension is linked to outcomes in the posttransplant period. Preoperative pulmonary vascular resistance is an independent r...

journal_title：Current opinion in cardiology

authors： Natale ME,Piña IL

更新日期：2003-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Bleeding has recently been identified as a major adverse outcome in patients with acute coronary syndromes. In this review, the importance of the association of bleeding with mortality and strategies to reduce bleeding with percutaneous coronary intervention are discussed. RECENT FINDINGS:Nine trials...

journal_title：Current opinion in cardiology

authors： White HD

更新日期：2009-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this review is to focus specifically on the indications, evolution of technique, and results of surgical ablation for atrial fibrillation. RECENT FINDINGS:With the introduction of the Cox-Maze IV procedure utilizing bipolar radiofrequency ablation and cryoablation, long-term studies have d...

journal_title：Current opinion in cardiology

authors： Lawrance CP,Henn MC,Damiano RJ Jr

更新日期：2015-01-01 00:00:00

abstract：PURPOSE OF REVIEW:To evaluate whether long-term antiplatelet therapy may be effective and well tolerated. RECENT FINDINGS:Five important studies assessed the efficacy and safety of clopidogrel therapy in different settings. However, the problems concerning the duration of therapy are based substantially on the Clopido...

journal_title：Current opinion in cardiology

authors： Bolognese L,Angiolillo DJ

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:We provide a concise review of recent studies focusing on the management of patients with acute heart failure (AHF). RECENT FINDINGS:In well designed randomized trials, no mortality benefit has been observed with the use of diuretics, ultrafiltration, inotropes and vasodilators in AHF. Recent trials ...

journal_title：Current opinion in cardiology

authors： Rayner-Hartley E,Virani S,Toma M

更新日期：2018-03-01 00:00:00

abstract：:The treatment of ischemic heart disease by coronary artery bypass grafting remains under intense scrutiny. A better understanding of the long-term outcome for particular patient subgroups will allow a more appropriate choice to be made among the options of coronary artery bypass grafting, angioplasty, or continued med...

journal_title：Current opinion in cardiology

authors： Kanagasabay RR,Parker DJ

更新日期：1996-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite progressive improvement in surgical results, hypoplastic left heart syndrome remains one of the congenital heart abnormalities with the greatest morbidity and mortality. Hybrid approaches to management, combining surgical and interventional catheterization procedures, have been introduced to m...

journal_title：Current opinion in cardiology

authors： Gutgesell HP,Lim DS

更新日期：2007-03-01 00:00:00

abstract：:This review of advances made toward understanding the molecular basis of congenital heart disease covers studies on subjects ranging from atrioventricular septal defects to zebrafish models. Genetically abnormal mice with atrioventricular septal defects have abnormal endocardial cushion development with the delayed ap...

journal_title：Current opinion in cardiology

authors： Gelb BD

更新日期：1997-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Thrombus formation, usually on a ruptured atherosclerotic plaque, is pivotal in the pathogenesis of ST segment elevation myocardial infarction (STEMI). This thrombus formation provides the milieu for re-occlusion of the infarct-related artery, the main location of re-infarction post-STEMI. Although ra...

journal_title：Current opinion in cardiology

authors： French JK,Burgess S,Chew DP

更新日期：2015-07-01 00:00:00

abstract：:Venous graft disease is a thromboproliferative process and places a serious limitation on the symptom-free survival of patients after coronary artery bypass grafting. The efficacy of antithrombotics, especially during the first year after surgery, is suggested by an understanding of the four described phases of diseas...

journal_title：Current opinion in cardiology

authors： Schussheim AE,Fuster V

更新日期：1998-11-01 00:00:00

abstract：:In addition to necrosis, apoptosis makes a significant contribution to cell death following acute myocardial ischemia; apoptosis is particularly enhanced during reperfusion. Several studies are beginning to indicate that the cell death by apoptosis may be preventable. A boost in the research in this direction has been...

journal_title：Current opinion in cardiology

authors： Garg S,Hofstra L,Reutelingsperger C,Narula J

更新日期：2003-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The efficacy of anticoagulation for valvular prostheses is the result of a delicate balance between the risk of thromboembolic (TE) events and bleeding. Here, we review data on anticoagulation for valve prostheses with a focus on clinical trials that address key unanswered questions. RECENT FINDINGS:...

journal_title：Current opinion in cardiology

authors： Yanagawa B,Whitlock RP,Verma S,Gersh BJ

更新日期：2016-03-01 00:00:00

abstract：PURPOSE OF REVIEW:There is controversy regarding the optimal choice of prosthetic valves in patients less than 65 years of age requiring mitral valve replacement (MVR). Recently, trends for valve replacement are moving towards biological prosthesis also in younger patients, which is justified by the fact that a later v...

journal_title：Current opinion in cardiology

authors： Reineke DC,Heinisch PP,Winkler B,Englberger L,Carrel TP

更新日期：2015-03-01 00:00:00

abstract：:Ventricular remodeling refers to changes in ventricular geometry, volume, mass, and myocellular structure in response to myocardial injury or alteration in loading conditions. Although initially adaptive as a consequence of the initial damage to the myocardium, progressive ventricular remodeling is ultimately a malada...

journal_title：Current opinion in cardiology

authors： Bozkurt B

更新日期：1999-05-01 00:00:00

abstract：:The mechanisms of pathogenesis of myocarditis have remained elusive. Despite the demonstration a decade ago that persistent viral infection of the myocardium occurred in many patients, a clear description of the pathologic progression has not been forthcoming. Over the past year, a number of studies have added to the ...

journal_title：Current opinion in cardiology

authors： Bowles NE,Towbin JA

更新日期：1998-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Statins are widely utilized for low-density lipoprotein lowering and for prevention of atherosclerotic cardiovascular disease. Although these drugs have a good safety record, increased risk of developing diabetes during extended use has recently garnered attention. Here we review clinical trial eviden...

journal_title：Current opinion in cardiology

authors： Sampson UK,Linton MF,Fazio S

更新日期：2011-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe the electrophysiological profile and the clinical portfolio of dronedarone, a new multichannel-blocking antiarrhythmic drug developed for the treatment of atrial fibrillation. RECENT FINDINGS:Dronedarone is a derivative of amiodarone that is free of iodine and less lipophilic. The drug ha...

journal_title：Current opinion in cardiology

authors： Duray GZ,Ehrlich JR,Hohnloser SH

更新日期：2010-01-01 00:00:00

abstract：:The presence, and in many cases the regulated synthesis, of components of the renin-angiotensin system have been demonstrated in multiple tissues, indicating the existence of tissue angiotensin-generating systems. These vary with respect to which renin-angiotensin system components are synthesized locally and which ar...

journal_title：Current opinion in cardiology

authors： Re RN

更新日期：2001-11-01 00:00:00

abstract：PURPOSE OF REVIEW:The health benefits of physical activity and exercise are clear; virtually everyone can benefit from becoming more physically active. Most international guidelines recommend a goal of 150 min/week of moderate-to-vigorous intensity physical activity. Many agencies have translated these recommendations ...

journal_title：Current opinion in cardiology

authors： Warburton DER,Bredin SSD

更新日期：2017-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Myocardial fibrosis is a common feature of many cardiomyopathies, including hypertrophic cardiomyopathy. Myocardial fibrosis has been shown to be reversible and treatable with timely intervention. Although early detection and assessment of fibrosis is crucial, adequate diagnostics are still in develop...

journal_title：Current opinion in cardiology

authors： Won S,Davies-Venn C,Liu S,Bluemke DA

更新日期：2013-05-01 00:00:00

abstract：PURPOSE OF REVIEW:This review discusses the role of statin therapy in patients with acute coronary syndromes. These drugs modulate endothelial function and stabilize atherosclerotic plaque by inhibiting oxidative stress and inflammation and may provide a relevant clinical benefit in unstable patients. RECENT FINDINGS:...

journal_title：Current opinion in cardiology

authors： Nusca A,Melfi R,Patti G,Di Sciascio G

更新日期：2010-07-01 00:00:00

abstract：:Recent epidemiologic studies of the risk factors for early and late phases of transplant coronary artery disease (TxCAD) have identified metabolic abnormalities such as hyperlipidemia and insulin resistance as important risk factors, independent of rejection. In randomized trials, calcium channel blockers and hydroxym...

journal_title：Current opinion in cardiology

authors： Valantine-von Kaeppler HA

更新日期：1998-03-01 00:00:00

abstract：:Myocardial contrast echocardiography (MCE) is an emerging technique in which microbubble contrast agents are visualized in the coronary microvasculature. MCE is an ideal modality for the noninvasive evaluation of acute coronary syndromes because it provides portable, simultaneous assessment of regional wall motion and...

journal_title：Current opinion in cardiology

authors： Ward RP,Lang RM

更新日期：2002-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the current evidence regarding the relationship between omega-3 fatty acid intake and atherosclerotic cardiovascular disease (ASCVD) risk. RECENT FINDINGS:Combined results from randomized controlled trials using low-dosage (≤1.8 g/day of ethyl esters) eicosapentaenoic acid (EPA) or EPA + d...

journal_title：Current opinion in cardiology

authors： Maki KC,Dicklin MR

更新日期：2020-07-01 00:00:00

abstract：:The human race is genetically programmed to consume less than 1 g of salt per day. In most human populations, the diet contains 6 to 12 g of salt per day and, in contrast to populations that consume less than 3 g of salt per day, their blood pressure rises with age. Independent of the rise in blood pressure, a high-sa...

journal_title：Current opinion in cardiology

authors： De Wardener HE,MacGregor GA

更新日期：2002-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update of the literature describing the link between lipoprotein a and vascular disease. RECENT FINDINGS:There is evidence that elevated plasma lipoprotein a levels are associated with coronary heart disease, stroke and other manifestations of atherosclerosis. Several mechanisms may be ...

journal_title：Current opinion in cardiology

authors： Tziomalos K,Athyros VG,Wierzbicki AS,Mikhailidis DP

更新日期：2009-07-01 00:00:00

abstract：:Although activation of the endocrine renin-angiotensin system with consequent vasoconstriction and salt retention have long been known as the hallmarks of the early phase of renovascular hypertension, the recent recognition of a local vascular angiotensin system and the understanding of the process of vascular remodel...

journal_title：Current opinion in cardiology

authors： Ma AO,Gibbons GH

更新日期：1994-09-01 00:00:00

abstract：PURPOSE OF REVIEW:To describe recent advancements in cardiovascular genetics made possible by leveraging next-generation sequencing (NGS), and to provide a framework for practical applications of genetic testing for hypertrophic (HCM), dilated (DCM), and arrhythmogenic right ventricular cardiomyopathies (ARVC). RECENT...

journal_title：Current opinion in cardiology

authors： Wilcox JE,Hershberger RE

更新日期：2018-05-01 00:00:00