Usefulness of basal B-type natriuretic peptide levels for the diagnosis of diastolic heart failure in young patients: an echocardiographic-catheterization study.

Abstract:

:The aim of the present study was to address the diagnostic relevance of B-type natriuretic peptide (BNP) for the diagnosis of diastolic heart failure (DHF) in young patients presenting with chronic, isolated dyspnea. We prospectively included 26 consecutive patients with a left ventricular ejection fraction >50% referred for catheterism. DHF was authenticated in 15 patients with an invasive left ventricular end-diastolic pressure >16 mmHg. By logistic regression analysis, BNP was predictive of DHF (p=0.03). A cut-off value of 31 pg/ml was 67% sensitive and 73% specific for the diagnosis (area under the ROC curve of 0.76 [0.55-0.9], p=0.007).

journal_name

Int J Cardiol

authors

Arques S,Jaubert MP,Bonello L,Roux E,Armero S,Sbragia P,Nicoud A,Paganelli F

doi

10.1016/j.ijcard.2009.03.127

subject

Has Abstract

pub_date

2010-11-05 00:00:00

pages

51-2

issue

1

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(09)00430-6

journal_volume

145

pub_type

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