Benefits and risks of corticosteroid prophylaxis in adult cardiac surgery: a dose-response meta-analysis.

abstract：:The quantitative approaches to the assessment of regional left ventricular (LV) function described in the preceding paper were applied in a well-defined population of patients with coronary artery disease. Two groups were chosen by electrocardiographic and angiographic criteria: group 1 had infarction and regional wal...

journal_title：Circulation

authors： Parisi AF,Moynihan PF,Folland ED,Feldman CL

更新日期：1981-04-01 00:00:00

abstract：:The release of the American Heart Association's 2030 Impact Goal and associated metrics for success underscores the importance of cardiovascular health and cardiovascular disease surveillance systems for the acquisition of information sufficient to support implementation and evaluation. The aim of this policy statemen...

journal_title：Circulation

authors： Roger VL,Sidney S,Fairchild AL,Howard VJ,Labarthe DR,Shay CM,Tiner AC,Whitsel LP,Rosamond WD,American Heart Association Advocacy Coordinating Committee.

更新日期：2020-03-03 00:00:00

abstract：BACKGROUND:Children awaiting heart transplantation have severe limitations in their ability to exercise. The purpose of this study was to assess exercise capacity after pediatric heart transplantation and to identify factors influencing exercise performance. METHODS AND RESULTS:Progressive cycle ergometry testing was ...

journal_title：Circulation

authors： Hsu DT,Garofano RP,Douglas JM,Michler RE,Quaegebeur JM,Gersony WM,Addonizio LJ

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Despite successful restoration of epicardial vessel patency with primary percutaneous coronary intervention, coronary microvascular injury occurs in a large proportion of patients with ST-segment-elevation myocardial infarction, adversely affecting clinical and functional outcome. Ticagrelor has been reporte...

journal_title：Circulation

authors： van Leeuwen MAH,van der Hoeven NW,Janssens GN,Everaars H,Nap A,Lemkes JS,de Waard GA,van de Ven PM,van Rossum AC,Ten Cate TJF,Piek JJ,von Birgelen C,Escaned J,Valgimigli M,Diletti R,Riksen NP,van Mieghem NM,Nijveldt R,

更新日期：2019-01-29 00:00:00

abstract：:The directions and magnitudes of time-normalized P, QRS, and ST vectors, and other ECG parameters were analyzed during and after multistage exercise in 56 ostensibly healthy men aged 23 to 62. By selective averaging with a digital computer system a single representative beat was obtained from each stage. Measurements ...

journal_title：Circulation

authors： Simoons ML,Hugenholtz PG

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:Natural history of aortic dissection (AD) with intimal tear in the descending or abdominal aorta and retrograde extension into the ascending aorta (retrograde AD) remains unknown. The purpose of this study was to elucidate medium-term prognosis of patients with retrograde AD. METHODS AND RESULTS:Study popul...

journal_title：Circulation

authors： Kaji S,Akasaka T,Katayama M,Yamamuro A,Yamabe K,Tamita K,Akiyama M,Watanabe N,Tanemoto K,Morioka S,Yoshida K

更新日期：2003-09-09 00:00:00

abstract：BACKGROUND:We surveyed the national experience of coronary artery bypass grafting (CABG) for coronary sequelae of Kawasaki disease (kDa) in 2002. METHODS AND RESULTS:A questionnaire was returned from 323/552 (59%) institutions. Two hundred forty-four patients (188 male 56 female) since 1975 were identified. The mean n...

journal_title：Circulation

authors： Tsuda E,Kitamura S,Cooperative Study Group of Japan.

更新日期：2004-09-14 00:00:00

abstract：:In a placebo-controlled, randomized, cross-over, double-blind study of 12 patients with stable exertional angina, we measured at rest and during bicycle exercise the effects of 20 mg of nifedipine administered sublingually on hemodynamics and systemic and regional oxygen extraction and metabolism. Nifedipine decreased...

journal_title：Circulation

authors： Choong CY,Roubin GS,Shen WF,Harris PJ,Kelly DT

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:The patency of AV expanded polytetrafluoroethylene (ePTFE) grafts for hemodialysis is impaired by intimal hyperplasia (IH) at the venous outflow tract. The absence of a functional endothelial monolayer on the prosthetic grafts is an important stimulus for IH. In the present study, we evaluated the feasibilit...

journal_title：Circulation

authors： Rotmans JI,Heyligers JM,Verhagen HJ,Velema E,Nagtegaal MM,de Kleijn DP,de Groot FG,Stroes ES,Pasterkamp G

更新日期：2005-07-05 00:00:00

abstract：BACKGROUND:Guidelines for the management of patients with suspected coronary artery disease (CAD) rely on the age, sex, and angina typicality-based pretest probabilities of angiographically significant CAD derived from invasive coronary angiography (guideline probabilities). Reliability of guideline probabilities has n...

journal_title：Circulation

authors： Cheng VY,Berman DS,Rozanski A,Dunning AM,Achenbach S,Al-Mallah M,Budoff MJ,Cademartiri F,Callister TQ,Chang HJ,Chinnaiyan K,Chow BJ,Delago A,Gomez M,Hadamitzky M,Hausleiter J,Karlsberg RP,Kaufmann P,Lin FY,Maffei E

更新日期：2011-11-29 00:00:00

abstract：BACKGROUND:During ischemia, the intracellular calcium and inorganic phosphate (P(i)) concentrations rise and pH falls. We investigated the effects of these changes on force development in donor and failing human hearts to determine if altered contractile protein composition during heart failure changes the myocardial r...

journal_title：Circulation

authors： van Der Velden J,Klein LJ,Zaremba R,Boontje NM,Huybregts MA,Stooker W,Eijsman L,de Jong JW,Visser CA,Visser FC,Stienen GJ

更新日期：2001-09-04 00:00:00

abstract：:Paclitaxel drug-coated balloons and drug-eluting stents became commercially available for the treatment of intermittent claudication in 2015 and 2012, respectively. Both devices demonstrated superiority in limb revascularization compared with non-paclitaxel-coated devices and were rapidly accepted into clinical practi...

journal_title：Circulation

authors： Beckman JA,White CJ

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:Whether and to what extent complement is activated in acute myocardial infarction (AMI) and how it contributes to inflammation of the ischemic area are not yet clear. Fibrinolytic agents used for thrombolysis are known to activate complement in vitro and may contribute to its activation in vivo. The aim of t...

journal_title：Circulation

authors： Frangi D,Gardinali M,Conciato L,Cafaro C,Pozzoni L,Agostoni A

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:At physiological concentrations, 17beta-estradiol selectively enhances endothelium-dependent coronary vasodilation by an unknown mechanism in postmenopausal women. METHODS AND RESULTS:To assess the contribution of nitric oxide (NO) to the vascular effects of estradiol, we measured coronary epicardial and mi...

journal_title：Circulation

authors： Guetta V,Quyyumi AA,Prasad A,Panza JA,Waclawiw M,Cannon RO 3rd

更新日期：1997-11-04 00:00:00

abstract：BACKGROUND:The evolution of cell phenotypes and matrix architecture in cardiac valves during fetal maturation and postnatal adaptation through senescence remains unexplored. METHODS AND RESULTS:We hypothesized that valvular interstitial (VIC) and endothelial cell (VEC) phenotypes, critical for maintaining valve functi...

journal_title：Circulation

authors： Aikawa E,Whittaker P,Farber M,Mendelson K,Padera RF,Aikawa M,Schoen FJ

更新日期：2006-03-14 00:00:00

abstract：BACKGROUND:Despite a recent American Heart Association (AHA) consensus statement emphasizing the importance of resistant hypertension, the incidence and prognosis of this condition are largely unknown. METHODS AND RESULTS:This retrospective cohort study in 2 integrated health plans included patients with incident hype...

journal_title：Circulation

authors： Daugherty SL,Powers JD,Magid DJ,Tavel HM,Masoudi FA,Margolis KL,O'Connor PJ,Selby JV,Ho PM

更新日期：2012-04-03 00:00:00

abstract：BACKGROUND:Bias in studies of preventive medications can occur when healthier patients are more likely to initiate and adhere to therapy than less healthy patients. We sought evidence of this bias by examining associations between statin exposure and various outcomes that should not be causally affected by statin expos...

journal_title：Circulation

authors： Dormuth CR,Patrick AR,Shrank WH,Wright JM,Glynn RJ,Sutherland J,Brookhart MA

更新日期：2009-04-21 00:00:00

abstract：BACKGROUND:Several individual pharmacological agents, such as antiplatelet drugs, beta-blockers, ACE inhibitors, and lipid-lowering agents, have proven efficacy in reducing mortality in patients with acute coronary syndromes. However, the impact of the combination of these agents on clinical outcomes has not been studi...

journal_title：Circulation

authors： Mukherjee D,Fang J,Chetcuti S,Moscucci M,Kline-Rogers E,Eagle KA

更新日期：2004-02-17 00:00:00

abstract：:This report describes clinical, morphological, and histological findings late (1.6-24.1 months [average, 8.2 months]) after clinically successful coronary balloon angioplasty in 20 necropsied patients with coronary angioplasty restenosis. Clinical evidence of restenosis occurred in 14 (70%) of patients, including six ...

journal_title：Circulation

authors： Waller BF,Pinkerton CA,Orr CM,Slack JD,VanTassel JW,Peters T

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Previous studies suggest that rigid fixation of the mitral annulus with an annuloplasty ring may impair left ventricular (LV) systolic performance. We used load-insensitive indexes of global and regional LV contractile mechanics to test the hypothesis that rigid fixation of the mitral annulus alters LV systo...

journal_title：Circulation

authors： Rayhill SC,Castro LJ,Nizyporuk MA,Ingels NB Jr,Daughters GT,Derby GC,Tye TL,Bolger AF,Miller DC

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Mild oxidation of LDL enhances its atherogenic potential and induces a synergistic interaction with serotonin (5HT) on vascular smooth muscle cell (VSMC) proliferation. Because of its complex chemical nature, the mitogenic components of mildly oxidized LDL (moxLDL) remain unclear. METHODS AND RESULTS:We exa...

journal_title：Circulation

authors： Watanabe T,Pakala R,Koba S,Katagiri T,Benedict CR

更新日期：2001-03-13 00:00:00

abstract：:The dynamics of acute mitral regurgitation were studied in six open-chest dogs in whom a portion of the anterior leaflet was excised. Phasic mitral and aortic flows were measured electromagnetically and left ventricular filling volume, regurgitant volume (RV) and forward stroke volume (SV) were calculated. The systoli...

journal_title：Circulation

authors： Yoran C,Yellin EL,Becker RM,Gabbay S,Frater RW,Sonnenblick EH

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:Mechanisms favoring the occurrence of paroxysmal atrial fibrillation (PAF) are complex and poorly defined. This study was designed to analyze dynamic changes in autonomic tone preceding the onset of PAF in a large group of patients. METHODS AND RESULTS:Holter tapes from 77 unselected consecutive patients (6...

journal_title：Circulation

authors： Bettoni M,Zimmermann M

更新日期：2002-06-11 00:00:00

abstract：BACKGROUND:Precise knowledge of the expected "normal" lumen diameter at a given coronary anatomic location is a first step toward developing a quantitative estimate of coronary disease severity that could be more useful than the traditional "percent stenosis." METHODS AND RESULTS:Eighty-three arteriograms were careful...

journal_title：Circulation

authors： Dodge JT Jr,Brown BG,Bolson EL,Dodge HT

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:ACE inhibitors exert both acute and chronic beneficial effects on cardiac function (eg, remodeling, diastolic dysfunction) in experimental studies and in patients. They inhibit the formation of angiotensin II as well as the degradation of endogenous bradykinin. We recently reported that bradykinin induces se...

journal_title：Circulation

authors： Anning PB,Grocott-Mason RM,Lewis MJ,Shah AM

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Recent studies suggest that the oxygen-sensing pathway consisting of transcription factor hypoxia-inducible factor and prolyl hydroxylase domain proteins (PHDs) plays a critical role in glucose metabolism. However, the role of adipocyte PHD in the development of obesity has not been clarified. We examined wh...

journal_title：Circulation

authors： Matsuura H,Ichiki T,Inoue E,Nomura M,Miyazaki R,Hashimoto T,Ikeda J,Takayanagi R,Fong GH,Sunagawa K

更新日期：2013-05-28 00:00:00

abstract：BACKGROUND:Factors predicting the occurrence of premature coronary artery disease (CAD) may not be quantitatively the same as those predicting CAD severity, particularly in women, in whom there have been few studies. METHODS AND RESULTS:To determine factors predictive of severity of CAD and of angina pectoris, we docu...

journal_title：Circulation

authors： Wang XL,Tam C,McCredie RM,Wilcken DE

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Monocarboxylate transporters (MCTs) mediate lactate transport across the plasma membrane of cells. The molecular mechanisms regulating monocarboxylate transport in smooth muscle cells (SMCs) remain poorly characterized. The aim of this study was to investigate the effects of DNA methylation on MCT expression...

journal_title：Circulation

authors： Zhu S,Goldschmidt-Clermont PJ,Dong C

更新日期：2005-08-30 00:00:00

abstract：BACKGROUND:The suggestion that increased QT dispersion (QTD) is due to increased differences in local action potential durations within the myocardium is wanting. An alternative explanation was sought by relating QTD to vectorcardiographic T-loop morphology. METHODS AND RESULTS:The T loop is characterized by its ampli...

journal_title：Circulation

authors： Kors JA,van Herpen G,van Bemmel JH

更新日期：1999-03-23 00:00:00

abstract：:A significant fraction of patients in whom mechanical left ventricular assist devices are implanted for refractory cardiac failure after open heart surgery have had the complication of right heart failure. To evaluate the effects of left ventricular assistance and pressure unloading on right ventricular function, we p...

journal_title：Circulation

authors： Farrar DJ,Compton PG,Dajee H,Fonger JD,Hill JD

更新日期：1984-10-01 00:00:00