Abstract:
:The autoimmune polyendocrinopathy syndromes are variable in presentation and can be challenging to diagnose and manage. Diagnosis of the type 1 autoimmune polyendocrinopathy syndrome can be difficult at an early age when often only one manifestation is present, and it may take years for others to appear. Increased awareness of polyendocrinopathy syndromes, combined with analysis of specific autoantibodies and molecular genetics, should help earlier diagnosis of these conditions and prevent serious complications. Further definition of susceptibility genes and autoantigens, as well as a better understanding of the pathogenesis, is required to improve the diagnosis and management of these patients.
journal_name
Endocrinol Metab Clin North Amjournal_title
Endocrinology and metabolism clinics of North Americaauthors
Owen CJ,Cheetham TDdoi
10.1016/j.ecl.2009.01.007subject
Has Abstractpub_date
2009-06-01 00:00:00pages
419-36, xissue
2eissn
0889-8529issn
1558-4410pii
S0889-8529(09)00008-5journal_volume
38pub_type
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