Abstract:
OBJECTIVES:Rhinitis is common, but the risk factors are not well described. To investigate the association between current rhinitis and pesticide use, we used data from 2245 Iowa commercial pesticide applicators in the Agricultural Health Study. METHODS:Using logistic regression models adjusted for age, education and growing up on a farm, we evaluated the association between current rhinitis and 34 pesticides used in the past year. RESULTS:74% of commercial pesticide applicators reported at least one episode of rhinitis in the past year (current rhinitis). Five pesticides used in the past year were significantly positively associated with current rhinitis: the herbicides 2,4-D, glyphosate and petroleum oil, the insecticide diazinon and the fungicide benomyl. The association for 2,4-D and glyphosate was limited to individuals who used both in the past year (OR 1.42, 95% CI 1.14 to 1.77). Both petroleum oil and diazinon showed consistent evidence of an association with rhinitis, based on both current use and exposure-response models. We saw no evidence of confounding by common agricultural rhinitis triggers such as handling grain or hay. CONCLUSIONS:Exposure to pesticides may increase the risk of rhinitis.
journal_name
Occup Environ Medjournal_title
Occupational and environmental medicineauthors
Slager RE,Poole JA,LeVan TD,Sandler DP,Alavanja MC,Hoppin JAdoi
10.1136/oem.2008.041798subject
Has Abstractpub_date
2009-11-01 00:00:00pages
718-24issue
11eissn
1351-0711issn
1470-7926pii
oem.2008.041798journal_volume
66pub_type
杂志文章abstract:OBJECTIVE:To study the effect on the incidence of cancer of exposure to chemicals handled in the leather tanning industry. MATERIALS AND METHODS:A case-control study was performed within a cohort of 2487 workers employed for at least six months during the period 1900-89 in three Swedish leather tanneries. 68 cancer ca...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.53.7.463
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND:It has been speculated on theoretical grounds that biomarkers are superior surrogates for chemical exposures to air samples in epidemiology studies. METHODS AND RESULTS:Biomarkers were classified according to their position in the exposure-disease continuum-that is, parent compound, reactive intermediate, s...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.013102
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:Fetal growth restriction has been inconsistently associated with maternal exposure to elevated levels of traffic-related air pollution. OBJECTIVE:We investigated the relationship between an individualised measure of fetal growth and maternal exposure to a specific marker for traffic-related air pollution. ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2011-100509
更新日期:2012-11-01 00:00:00
abstract::The association between occupational exposure to airway irritants and the prevalence of chronic respiratory symptoms and level of lung function, and whether these associations were modified by airway hyperresponsiveness, smoking, and a history of allergy were studied in 668 workers from synthetic fibre plants. Respira...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.1.3
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVES:Organic acid anhydrides are potential sensitisers and cause occupational airway diseases. In an intervention study the efficacy of measures of hygiene at the workplace and possible selection bias were investigated. METHODS:A first investigation with 110 workers exposed to hexahydrophthalic acid anhydride (H...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.56.3.202
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVE:Occupational dust exposure has been associated with accelerated lung function decline, which in turn is associated with overall morbidity and mortality. In the current study, we assess potential benefits on lung function of hypothetical interventions that would reduce occupational exposure to fine particulate...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2019-105908
更新日期:2019-12-01 00:00:00
abstract:AIMS:To investigate the effects of smoking and personal hygienic behaviour on blood lead (BPb) and free erythrocyte protoporphyrin levels (FEP) in lead exposed workers. METHODS:Subjects were 105 lead exposed male workers in a battery recycling plant during the years 2000-03. BPb and FEP were measured as part of the on...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2004.019513
更新日期:2005-05-01 00:00:00
abstract::Community based case-control studies are an efficient means to study disease aetiologies, and may be the only practical means to investigate rare diseases. However, exposure assessment remains problematic. We review the literature on the validity and reliability of common case-control exposure assessment methods: occu...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,评审
doi:10.1136/oem.59.9.575
更新日期:2002-09-01 00:00:00
abstract:AIMS:To determine obstacles for return-to-work in disability management of low back pain patients sicklisted for 3-4 months. METHODS:A cohort of 467 low back pain patients sicklisted for 3-4 months was recruited. A questionnaire was sent to their occupational physicians (OPs) concerning the medical management, obstacl...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.59.11.729
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVES:Foundry work is a risk factor for lung cancer; however, the association with welding is unclear, as smoking is common among metalworkers and may mask the relationship. We evaluated whether history of welding and foundry work, independently and jointly, and employment duration were associated with lung cancer...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,随机对照试验
doi:10.1136/oemed-2016-104168
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVES:To investigate the frequency, circumstances, and causes of occupational accidents aboard merchant ships in international trade, and to identify risk factors for the occurrence of occupational accidents as well as dangerous working situations where possible preventive measures may be initiated. METHODS:The s...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.59.2.85
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVES:To explore the significance of the increase in urinary excretion of the lysosomal enzyme beta-N-acetylglucosaminidase (NAG) at low exposures to cadmium (Cd) that is frequently found in the absence of any other sign of renal dysfunction. METHODS:The activity was measured of the two main isoenzymes of NAG (NA...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.52.3.177
更新日期:1995-03-01 00:00:00
abstract:OBJECTIVE:Depressive symptoms are associated with sickness absence, work disability and unemployment, but little is known about worklife expectancy (WLE). This study investigates the impact of depressive symptoms on the WLE of a large sample of Danish employees. METHODS:We used occupational health survey data of 11 96...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2019-105961
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:Night shift work has been classified as a probable human carcinogen by the International Agency for Research on Cancer, based on experimental studies and limited evidence on human breast cancer risk. Evidence at other cancer sites is scarce. We evaluated the association between night shift work and stomach c...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2016-103597
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:This study was undertaken to assess whether contaminated personal clothing worn beneath a coverall (normal workwear) is a source of potentially significant dermal exposure to polycyclic aromatic hydrocarbons (PAHs) in coal liquefaction workers. METHODS:An intervention study was conducted over a two week peri...
journal_title:Occupational and environmental medicine
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/oem.52.9.600
更新日期:1995-09-01 00:00:00
abstract::Aerosol sampling has evolved with changes in technology and our understanding of the importance of assessing the biologically relevant fractions of the total aerosol. During the past decade there has been international agreement on the definitions for the inhalable, thoracic, and respirable fractions and instruments h...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,评审
doi:10.1136/oem.56.11.747
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVES:Standardised mortality ratios (SMRs) play an important role in the epidemiological literature, particularly in evaluations of occupational hazards. While some authors have argued that comparisons of SMRs should be avoided, many investigators find such analyses appealing particularly when data are sparse. For...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2012-100792
更新日期:2013-02-01 00:00:00
abstract:OBJECTIVE:The aim was to investigate associations between exposure to mineral fibres and dust, and cancer in subsites within the large bowel. DESIGN:Pooled retrospective cohort studies. SUBJECTS AND SETTINGS:Blue collar workers, employed for at least one year in different trades; asbestos cement or cement workers (n ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.51.2.95
更新日期:1994-02-01 00:00:00
abstract:OBJECTIVES:Exposure to high-molecular-weight polycyclic aromatic hydrocarbons (PAHs) may cause cancer in chimney sweeps and creosote-exposed workers, however, knowledge about exposure to low-molecular-weight PAHs in relation to cancer risk is limited. In this study, we aimed to investigate occupational exposure to the ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2020-106413
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVES:Ammonium perfluorooctanoate (APFO) is a biopersistent surfactant used in the manufacture of several types of fluoropolymers. Based on previous findings of increased serum lipid levels associated with exposure to APFO, we evaluated ischaemic heart disease (IHD) mortality in a cohort of occupationally exposed ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2008.041582
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVES:The fit note, introduced in England, Wales and Scotland in 2010, was designed to change radically the sickness certification process from advising individuals on their inability to work to advising them on what they could do if work could be adapted. Our review aimed to evaluate the following: (1) Is the 'ma...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2017-104730
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVES:To investigate the occurrence of work related respiratory symptoms and to assess the effect of atopy in a group of trainee bakers. METHODS:A prospective study of work related respiratory symptoms among 125 trainee bakers who were investigated with a questionnaire plus skin prick test with wheat flour and al...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.57.1.58
更新日期:2000-01-01 00:00:00
abstract:AIMS:To study the risk of childhood cancer in relation to parental occupation and related exposures. METHODS:Self reported occupational data from mothers and fathers of 3838 children with cancer and 7629 control children were analysed. Odds ratios were calculated for 31 "occupational groups" by parent, diagnostic grou...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.60.12.901
更新日期:2003-12-01 00:00:00
abstract:OBJECTIVES:To determine the prevalence and risk factors for symptoms related to gloves, and the relation between symptoms and immunological evidence of type 1 hypersensitivity to latex in a United Kingdom health care setting. METHODS:A cross sectional survey was carried out among 773 employees at a British hospital. A...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.56.12.833
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVES:To evaluate the effects of chronic exposure to lead on the peripheral nervous system in lead workers. METHODS:Nerve conduction velocity and electromyographic studies were performed on 31 lead workers of a battery recycling factory and 31 sex and age matched controls. 25 cases with mild distal extensor weakn...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.52.6.415
更新日期:1995-06-01 00:00:00
abstract:AIMS:To assess the impact of newly introduced point-of-sale glass bottle recycling on indoor air quality and employee health. METHODS:Airborne exposures and both chronic and acute respiratory and somatic symptoms were surveyed among 226 employees at 36 randomly selected liquor stores with bottle recycling and in-house...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oem.2003.009753
更新日期:2004-07-01 00:00:00
abstract:OBJECTIVE:To assess the effectiveness of lumbar supports, education, and exercise in the prevention of back pain in industry. METHODS:A computerised search for controlled clinical trials was conducted. A criteria list was used to assess the methodological quality of the studies. The available evidence for the effectiv...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章,meta分析
doi:10.1136/oem.54.12.841
更新日期:1997-12-01 00:00:00
abstract:OBJECTIVES:Psychosocial work characteristics have been prospectively associated with depressive symptoms. However, methodological limitations have raised questions regarding causality. It is also unclear to what extent depressive symptoms affect the experience of the psychosocial work environment. We examined contempor...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2018-105450
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVES:Previous analyses of cataract in radiation-exposed populations have assessed relative risk; radiogenic excess additive risk (EAR), arguably of more public health importance, has not been estimated. Previous analysis of a large prospective cohort of US radiologic technologists (USRT) quantified excess relativ...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2019-105902
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVES:There is an ongoing debate regarding environmental health risks of exposures to dust and microbial agents from livestock farming in the Netherlands. The aims of the study were (1) to investigate associations between indicators of air pollution from livestock farms and asthma, allergic rhinitis and chronic ob...
journal_title:Occupational and environmental medicine
pub_type: 杂志文章
doi:10.1136/oemed-2013-101485
更新日期:2014-02-01 00:00:00