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Is the prevalence of specific types of congenital heart defects different for non-Hispanic white, non-Hispanic black and Hispanic infants?

Abstract：

BACKGROUND:Our purpose was to determine the prevalence of specific types of CHD among non-Hispanic (NH)-Black, NH-White, and Hispanic infants. METHODS:We conducted a retrospective cohort study with 9,352 singleton infants diagnosed with conotruncal, right or left obstructive or septal CHDs from the Florida Birth Defects Registry, born 1998-2003 to resident NH-White, NH-Black, and Hispanic women aged 15-49. Defect-specific prevalence rates, prevalence ratios and P-values were calculated for each type of CHD and by number of defects for each racial/ethnic group. RESULTS:Compared to NH-Whites, NH-Blacks had higher rates of pulmonary valve atresia/stenosis but lower frequency of aortic valve atresia/stenosis and ventricular septal defect. Hispanics had lower rates of aortic valve atresia/stenosis and atrioventricular septal defects than NH-Whites. CONCLUSIONS:Although few racial/ethnic differences in prevalence are present among infants with major CHD, observed differences are clinically meaningful. However, the underlying etiologies for the observed differences remain unknown.

journal_name

Matern Child Health J

journal_title

Maternal and child health journal

authors

Nembhard WN,Salemi JL,Wang T,Loscalzo ML,Hauser KW

doi

10.1007/s10995-009-0442-9

subject

Has Abstract

pub_date

2010-03-01 00:00:00

pages

184-93

issue

2

eissn

1092-7875

issn

1573-6628

journal_volume

14

pub_type

杂志文章

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