Abstract:
OBJECTIVES:The surgical treatment of congenital vascular malformations always bears the risk of severe bleeding. The aim of this study was to investigate the prevalence of haemostatic abnormalities in patients with congenital vascular malformations of the head and neck which could additionally complicate the complex surgery of vascular malformations. METHODS:Thirteen patients with congenital vascular malformations of the head and neck, who underwent scheduled surgery, were reviewed regarding their haemostatic tests, including prothrombin time, activated partial thromboplastin time, fibrinogen level, platelet count, platelet function analyzer-epinephrine (PFA-Epi) and -adenosine diphosphate (ADP) (PFA-100), von Willebrand factor (vWF) and D-dimers. RESULTS:In six of 13 patients an impaired primary haemostasis was detected by prolonged PFA-Epi and one of these patients also had a slightly prolonged PFA-ADP. Additionally, two of the patients showed mild coagulation factor deficiency. One patient had a mild vWF deficiency that was not detected by PFA-100. CONCLUSION:Prior to surgery of congenital vascular malformations of the head and neck, a detailed coagulation analysis is needed in order to identify those patients at increased risk of bleeding. This proceeding is supported by the fact that a relevant portion of the patients with congenital vascular malformations of the head and neck show an impaired primary haemostasis.
journal_name
Phlebologyjournal_title
Phlebologyauthors
Wiegand S,Eivazi B,Karger R,Al Kadah B,Sesterhenn AM,Werner JAdoi
10.1258/phleb.2008.008019subject
Has Abstractpub_date
2009-02-01 00:00:00pages
38-42issue
1eissn
0268-3555issn
1758-1125pii
24/1/38journal_volume
24pub_type
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