Abstract:
:Chondroitin sulphate (CS) is widely consumed orally by humans, and non-humans as it is believed to be beneficial for those with joint-related pathologies. Data concerning the functions of chondroitin sulphate in this, and other, biological systems are being actively extended. However, it is important to appreciate that chondroitin sulphate molecules represent a heterogeneous population the structure of which varies with source. As commercially available chondroitin sulphate is derived from a range of sources, and the molecular functions of chondroitin sulphate depend upon the structure, there are a range of structures available with differing potential for therapeutic impacts on a range of pathologies. While the safety of CS is not presently in doubt, poor quality finished products have the potential to compromise clinical and lab-based studies and will fail to give consumers all of the benefits available. Major parameters including bioavailability and uptake have been studied but it is clear that significant challenges remain in the identification of composition, sequence and size impacts on function, understanding how the consumed material is altered during uptake and travels to a site of action and how it exerts an influence on biological processes. If we understand these factors it may be possible to predict impacts upon biological processes and identify specific chondroitin sulphate structures which may target specific pathologies.
journal_name
Complement Ther Medjournal_title
Complementary therapies in medicineauthors
Lauder RMdoi
10.1016/j.ctim.2008.08.004subject
Has Abstractpub_date
2009-01-01 00:00:00pages
56-62issue
1eissn
0965-2299issn
1873-6963pii
S0965-2299(08)00123-4journal_volume
17pub_type
杂志文章,评审abstract:OBJECTIVES:This study sought to compare the effects of multi-point ear and body acupressure on labor pain and the duration of labor active phase. DESIGN:Three-armed randomized controlled trial. SETTING:Kowsar Hospital, Qazvin, Iran. INTERVENTION:Participants in the body acupressure group received acupressure on GB21...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2020.102413
更新日期:2020-06-01 00:00:00
abstract:AIM:To clarify the reasons underlying people's use of medical herbalism in the context of contemporary U.K. health care. DESIGN:This qualitative, interpretative study recruited 19 adults who were consulting with registered medical herbalists in a region of southern England. Participants were interviewed about their ex...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2009.08.001
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVES:This qualitative study aimed to explore medical specialists' perspectives on a proposed academic integrative healthcare (IHC) centre to be established in their local district. METHODS:A convenience sample of medical specialists were recruited via direct email invitations that was augmented with snowball sam...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2020.102530
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Scant research has been undertaken regarding chiropractors' skills and knowledge associated with evidence-based practice (EBP), and their perceived barriers to EBP. These issues appear to have been examined in only one small qualitative study and one small study of chiropractors holding orthopaedic diplomas....
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2014.02.007
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVES:Our study aimed to correlate pulse wave parameters such as augmentation index (AI) and heart rate variability with traditional Chinese medicine (TCM) constitution for evaluating health status. DESIGN:Out of 177 subjects, 69 healthy subjects were enrolled in the present study, and others were excluded becaus...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2016.12.005
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Merkel cell carcinoma (MCC) is a rare, aggressive, neuroendocrine skin tumor with frequent local recurrence, lymph node involvement, distant metastasis, and a high mortality rate. Viscum album extracts (VAE) are a widely used adjunct in cancer treatment and show cytotoxic and immune-modulating effects. CASE...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2018.04.001
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVES:To establish the feasibility of conducting a randomised controlled trial to evaluate the efficacy of acupuncture in the treatment of mild-to-moderate depression. Control group intervention, blinding of treatment, outcome measures and the acceptability of such a trial amongst participants were key factors to ...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2007.07.005
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Colonic diverticula develop in at least 60% of elderly patients. Less than 25% of these develop diverticulitis. Recurrent episodes are experienced by about 13% of the symptomatic patients. The effect on prevention of recurrent diverticulitis of currently used therapies is controversial. Surgical colon resect...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2018.03.013
更新日期:2018-10-01 00:00:00
abstract::While the chronic effects of certain styles of yoga on cardiometabolic factors have been investigated, little is known about the acute effects of a single yoga session on these outcomes. Moreover, vinyasa yoga's potential to modulate cardiometabolic outcomes has not been established. The purpose of this study is to de...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2020.102585
更新日期:2020-10-07 00:00:00
abstract:OBJECTIVES:To characterize the application of traditional Chinese medicine (TCM) among pediatric patients. DESIGN AND SETTING:This study examined data sets from the National Health Insurance Research Database in Taiwan. Two cohorts, each with one million patients who were randomly sampled from the beneficiaries of the...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2014.04.002
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVES:To examine the long-term effects of foot-bathing therapy, using different water temperatures, on the sleep quality of older adults living in nursing homes. DESIGN:A quasi-experimental study design with non-equivalent control group. SETTINGS:Thirty participants were recruited from a nursing home in Gyeong-g...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2016.02.005
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Prenatal maternal stress is associated with adverse birth outcomes. Relaxation techniques might be effective in reducing stress during that period. The purpose of this study was to evaluate the effects of applied relaxation in reducing anxiety and stress in pregnant women in their second trimester, as well a...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2014.01.006
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:This is the first part of a larger spectrum systematic review which aims to identify and evaluates the effectiveness of all different non-pharmacological acupuncture techniques used for COPD. In this first publication, we describe the results of filiform needle acupuncture METHODS: Randomised controlled tria...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,meta分析
doi:10.1016/j.ctim.2019.08.016
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Despite several studies about the effects of saffron supplementation on serum concentrations of lipid and glucose profiles, no systematic study had summarized the findings. Therefore, we conduct current study to systematically summarize findings from studies about the effect of saffron supplementation on ser...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,meta分析
doi:10.1016/j.ctim.2019.07.017
更新日期:2019-12-01 00:00:00
abstract::Chamomile, as a rich source of phenolic compounds and terpenoids, seems to be an effective approach in the management of chronic conditions such as diabetes mellitus. The aim of this systematic review was to evaluate evidence from animal and human studies of the effects of chamomile on metabolic risk markers and compl...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2019.102284
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:Breast cancer survivors often turn to the internet as an information resource when deciding whether to use complementary and alternative medicine (CAM) but their use of online CAM-related resources is poorly understood. The objective was to explore breast cancer survivors' use of the internet when making deci...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2017.06.007
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVES:Examine the effectiveness of sacroiliac (SI) joint prolotherapy for SI joint instability, and characterize the patients most likely to benefit from this treatment. DESIGN:Retrospective cohort study. SETTING:Department of Veterans Affairs outpatient physical medicine clinic. INTERVENTIONS:Patients referred...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2018.01.014
更新日期:2018-04-01 00:00:00
abstract:OBJECTIVES:The study examines the difference in characteristics between primary care patients who turn to "religious resources for medical purposes" (RRMP) and those who turn to "complementary or alternative medicine" (CAM) services to cope with a physical or mental health problem. DESIGN AND SETTING:Data were collect...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2013.08.010
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVES:Mind-body practices (MBP), such as Yoga or Tai-Chi, have increased in popularity in the past 25 years in the US. These activities may help promote a less sedentary lifestyle and may have positive effects on health. The objective of the present study is to understand the prevalence and trends of MBP in US adu...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2020.102501
更新日期:2020-08-01 00:00:00
abstract:INTRODUCTION:Osteoarthritis (OA) is characterised by synovial joint pain, functional disability and affects ∼13 % of people worldwide, of which ∼16-27 % report Knee-OA (KOA). Glucosamine (Glu) is the most widely used nutraceutical treatment for OA despite a lack of scientific consensus, therefore alternative nutraceuti...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2020.102349
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVES:To examine changes in psychological and occupational wellbeing in education professionals that attended a brief yoga and mindfulness-based program. DESIGN:Pragmatic controlled trial comparing education professionals that attended a yoga mindfulness-based program (n = 9) to a waitlist control group (n = 22)....
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2020.102470
更新日期:2020-08-01 00:00:00
abstract:PURPOSE:The aim of present study was to review and categorize the clinical trials investigating the clinical effects of different botanical parts of dates compared with any controls. METHODS:All clinical trials (randomized, pilot, quasi-experimental, cross-over. and non-randomized clinical trials) evaluating the clini...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2020.102429
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Inconsistencies exist with regard to effect of maternal vitamin D supplementation on infant vitamin D status. The inconsistencies could be attributed to numerous factors, such as duration of intervention and dosage, among others. In this work, we conducted a systematic review and meta-analysis to determine t...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ctim.2020.102491
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the effects of Sanyinjiao (SP6) with electroacupuncture on labour pain in women during the labour process. METHODS:A total of 350 women in labour from three centres were randomly divided into the electroacupuncture group (acupuncture group), the sham electroacupuncture group (sham group) and the ...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ctim.2010.09.001
更新日期:2011-01-01 00:00:00
abstract:AIMS:To outline acupuncturists' perceptions of treating patients with rheumatoid arthritis (RA), exploring the impact of practitioner affiliation to a traditional or western theoretical base. METHODS:Qualitative study utilising Grounded Theory Method. Nineteen acupuncturists were chosen via theoretical sampling. In-de...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2006.09.008
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND:Bikram yoga may enhance health outcomes in healthy adults and those at risk for chronic disease, however, challenges remain in achieving optimal adherence to this practice. This study investigated factors influencing adherence to a 16-week Bikram yoga intervention in stressed and sedentary adults. METHODS:E...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2018.12.015
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:To describe the use of medicinal plants in patients with chronic kidney disease (CKD) in public healthcare centers in Peru. METHODS:A cross-sectional study was conducted in patients with CKD in healthcare centers of three Peruvian regions: Lima, Arequipa, and Ucayali. A structured questionnaire which include...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2019.102215
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Although clinical trials are needed to evaluate the efficacy of liquid herbal medicinal products, design of feasible placebos that mimic the appearance, taste, and smell of such products is particularly challenging. OBJECTIVE:The design and feasibility of a liquid placebo for STW5, an herbal medicinal produ...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ctim.2012.04.003
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVES:Idiopathic Environmental Intolerance (IEI) is an acquired disorder with multiple recurrent symptoms, which is associated with diverse environmental factors that are tolerated by the majority of people. IEI is an illness of uncertain aetiology, making it difficult to treat using conventional medicine. Therefo...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2012.07.005
更新日期:2012-12-01 00:00:00
abstract:OBJECTIVES:This pilot study analyses the effect and feasibility of hydrotherapeutic Kneipp arm affusions on secretory immunoglobulin A (sIgA) and classic cold symptoms in children 3-6 years of age. STUDY DESIGN:A controlled, non-randomized, clinical pilot study was undertaken. INTERVENTION:This descriptive hydrothera...
journal_title:Complementary therapies in medicine
pub_type: 杂志文章
doi:10.1016/j.ctim.2020.102637
更新日期:2020-11-28 00:00:00