Abstract:
:Two groups of retinal cone bipolar cells (CBCs) in rats were found to express voltage-gated Na+ channels. The axon terminals of the first group stratify in sublamina 2 of the inner plexiform layer (IPL) and partially overlap with the OFF-cholinergic band. This group was identified as type 3 CBCs. The axon terminals of the second group stratify in sublamina 3 of the IPL, slightly distal to the ON-cholinergic band. Cells of this second group resemble type 5 CBCs. In addition, we observed another group of ON-type CBCs with terminal stratification similar to that of the second group. However, this latter group did not show any Na+ current, instead exhibiting a large hyperpolarization-activated cyclic nucleotide-gated cation current, suggesting the existence of two subclasses of physiologically distinct type 5 CBCs. Both groups of Na+-expressing bipolar cells were capable of generating a rapid tetrodotoxin-sensitive action potential as revealed by current injection. Multiple spike-like potentials were also observed in some of these cells. Results of this study provide valuable insights into the function of voltage-gated Na+ channels of retinal bipolar cells in retinal processing.
journal_name
Vis Neuroscijournal_title
Visual neuroscienceauthors
Cui J,Pan ZHdoi
10.1017/S0952523808080851subject
Has Abstractpub_date
2008-09-01 00:00:00pages
635-45issue
5-6eissn
0952-5238issn
1469-8714pii
S0952523808080851journal_volume
25pub_type
杂志文章abstract::The discoloration illusion, a new visual phenomenon, is described. This phenomenon originates from the juxtaposition of eight chromatic parallel contours on a white background, creating a luminance gradient and enclosing a light red region. Under these conditions, the inner region appears white: the light red discolor...
journal_title:Visual neuroscience
pub_type: 杂志文章
doi:10.1017/S0952523806233406
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更新日期:2004-11-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2013-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/s0952523800008208
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pub_type: 杂志文章,评审
doi:10.1017/S0952523809090038
更新日期:2009-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/s0952523800001747
更新日期:1994-03-01 00:00:00
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更新日期:2003-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/s0952523800002558
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pub_type: 杂志文章
doi:10.1017/s095252389815304x
更新日期:1998-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1017/s0952523800004582
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doi:10.1017/s0952523800004405
更新日期:1989-08-01 00:00:00
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journal_title:Visual neuroscience
pub_type: 杂志文章
doi:
更新日期:2001-11-01 00:00:00
abstract::While color vision mediated by rod photoreceptors in dim light is possible (Kelber & Roth, 2006), most animals, including humans, do not see in color at night. This is because their retinas contain only a single class of rod photoreceptors. Many of these same animals have daylight color vision, mediated by multiple cl...
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doi:10.1017/S095252380808084X
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pub_type: 杂志文章
doi:10.1017/s095252380000403x
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pub_type: 临床试验,杂志文章
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更新日期:2005-11-01 00:00:00
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journal_title:Visual neuroscience
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更新日期:1997-09-01 00:00:00