Defining real change in measures of stereoacuity.

Abstract:

PURPOSE:To establish the thresholds for "real change" in stereoacuity by defining long-term test-retest variability as 95% limits of agreement for 4 stereoacuity tests. DESIGN:Retrospective cohort study. PARTICIPANTS AND CONTROLS:We identified 36 patients (median, 17 years; range, 7-76) with any type of stable strabismus who had stereoacuity measured on 2 consecutive visits. Stable strabismus was defined as angle of deviation within 5 prism diopters by simultaneous prism and cover test and prism and alternating cover test. METHODS:Stereoacuity was measured at near using the preschool Randot and the near Frisby stereotests and at distance using the Frisby-Davis distance (FD2) and the distance Randot stereotests. Stereoacuity was transformed to log units for analysis. The 95% limits of agreement were calculated based on a 1.96 multiple of the standard deviation of differences between test and retest. MAIN OUTCOME MEASURES:The 95% limits of agreement for change in stereoacuity thresholds at 2 consecutive visits. RESULTS:The 95% limits of agreement were 0.59 log arcsec for the preschool Randot, 0.24 for the near Frisby, 0.68 for the FD2, and 0.46 for the distance Randot. These values correspond with the following octave steps (doublings of threshold; e.g., 200-400 arcsec): preschool Randot, 1.95; near Frisby, 0.78; FD2, 2.27; and distance Randot, 1.52. CONCLUSIONS:A change of approximately 2 octaves of stereoacuity threshold are needed to exceed test-retest variability for most stereoacuity tests. Changes <2 octaves cannot be distinguished from test-retest variability. When used to guide patient management, caution should be taken in interpreting changes in stereoacuity of <2 octaves. FINANCIAL DISCLOSURE(S):The authors have no proprietary or commercial interest in any materials discussed in this article.

journal_name

Ophthalmology

journal_title

Ophthalmology

authors

Adams WE,Leske DA,Hatt SR,Holmes JM

doi

10.1016/j.ophtha.2008.09.012

subject

Has Abstract

pub_date

2009-02-01 00:00:00

pages

281-5

issue

2

eissn

0161-6420

issn

1549-4713

pii

S0161-6420(08)00900-7

journal_volume

116

pub_type

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