Abstract:
:Systems biology and the Herbalome Project have good prospects if the specific episteme-method approach of traditional Chinese medicine (TCM) is taken into serious consideration. TCM takes advantage of a specific holistic method, which is based on the episteme method approach derived from the conceptions of unceasing movement and dynamic holism, to handle the diagnosis and treatments of certain diseases. Although the episteme method approach of TCM is quite different from that of modern medicine, some recent investigations have in principle clarified the episteme method characters of TCM. By means of high-tech purification methods, additional drugs than only artemisinin (qing hao-su) from TCM can be expected in the near future.
journal_name
Arch Med Resjournal_title
Archives of medical researchauthors
Liang Tdoi
10.1016/j.arcmed.2008.09.006subject
Has Abstractpub_date
2009-01-01 00:00:00pages
62-3issue
1eissn
0188-4409issn
1873-5487pii
S0188-4409(08)00245-2journal_volume
40pub_type
杂志文章abstract:BACKGROUND AND AIMS:Vardenafil has been found to be potent in pulmonary hypertension; however, the underlying mechanisms remain poorly understood. To address this issue, we investigated the underlying mechanisms of vardenafil in the contribution of Ca(2+) signaling and mobilization in modifying vasoconstriction of pulm...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2012.05.004
更新日期:2012-05-01 00:00:00
abstract::Classical descriptions of the pathology of amebiasis portray the parasite as the cause of tissue damage and destruction, and in recent years a number of amebic molecules have been identified as virulence factors. In this review we describe a series of experiments that suggest a more complex host-parasite relation, at ...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:10.1016/j.arcmed.2005.10.007
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND AND AIMS:The pathogenesis of coronary artery ectasia (CE) is poorly understood. An underlying inflammatory process is suspected; current therapy aims to prevent thrombotic events. Presently, there is no evidence to support an anti-inflammatory approach for CE patients. We undertook this study to determine th...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2014.07.002
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:It remains unclear whether the activation of kappa-opioid receptors has strong hypotensive effects under hypertensive condition, and the underlying mechanisms have not yet been investigated. Therefore, the present study is designed to use spontaneously hypertensive rats (SHR) to investigate the effects of a ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2007.04.009
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND AND AIMS:Bacteremia is a common serious manifestation of disease in the intensive care unit (ICU), which requires quick and accurate determinations of pathogens to select the appropriate antibiotic treatment. To overcome the shortcomings of traditional bacterial culture (BC), we have adapted next-generation ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2016.08.004
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Annually, there are more than 6 million deaths from a type of malignant neoplasia worldwide. In developing countries, the highest rates of incidence of malignant neoplasias are uterine cervical cancer, stomach, lung, esophagus, pharynx, and liver cancers. Recent estimates on the incidence of cancer worldwide...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-4409(01)00290-9
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:Selenoproteins S (SELS or VIMP) may regulate cytokine production, and thus play a key role in the control of the inflammatory response. METHODS:This study consisted of 136 Iranian patients with cardiovascular disease (65 MetS-affected and 71 MetS un-affected individuals) in the selengene study. Expression o...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2020.05.005
更新日期:2020-08-01 00:00:00
abstract::Clinical research in Internal Medicine has provided many scientific advances during the past few years. However, the newly generated information overrides the time available to read all of the medical literature regarding advances in Internal Medicine. The goal of this review is to summarize some of the most relevant ...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Supplementation with n3 long-chain polyunsaturated fatty acids (n3-LCPUFA) appears to affect body weight, adipokines, and insulin resistance (IR) in obese individuals. However, it is unclear whether the effect on IR is independent of weight loss and if the same effect is observed in children. We und...
journal_title:Archives of medical research
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.arcmed.2011.06.010
更新日期:2011-08-01 00:00:00
abstract::A definitive single hypothesis about HIV pathogenesis is still lacking in specialized literature. Rather, a picture of the extreme complexity in AIDS causality ensues from the extensive information available. This article contains an outline of the most relevant data on the subject of AIDS pathogenesis, organized into...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:
更新日期:1996-07-01 00:00:00
abstract:BACKGROUND AND AIMS:We undertook this study to assess the effects of omega-3 polyunsaturated fatty acids (PUFAs) (administered at ≥2.7 g/day) for a minimum duration of 3 months on clinical outcomes in patients with rheumatoid arthritis (RA). METHODS:The authors surveyed randomized controlled trials (RCTs) that examine...
journal_title:Archives of medical research
pub_type: 杂志文章,meta分析
doi:10.1016/j.arcmed.2012.06.011
更新日期:2012-07-01 00:00:00
abstract::The number of patients requiring lung transplantation is increasing, with a significant unmet demand for grafts. Ex vivo lung perfusion has been developed to increase graft recruitment. The major complications of lung transplantation include chronic allograft dysfunction (CLAD) whose cumulative incidence ranges from 4...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2015.03.004
更新日期:2015-04-01 00:00:00
abstract::This study evaluated the attachment, chemoattractive, proliferative and mineralization inductive potential of a bovine cementum extract (CPE) on newborn murine dental follicle cells (MDFC) in vitro. Cementum extract was partially purified by DEAE-cellulose chromatography. A band representing an M(r) of 55,000 was exci...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract:BACKGROUND:Occult hepatitis B infection (OBI) is defined as a form of hepatitis in which, despite absence of detectable HBsAg, HBV-DNA is present in peripheral blood of patients. The main aim of this study was to determine an association between polymorphisms in +801 of CXCL12 (SDF-1α) and its serum level in OBI patien...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2010.07.001
更新日期:2010-07-01 00:00:00
abstract::Organic solvents cause injury to lipids of neuronal and glial membranes. A well known characteristic of workers exposed to thinner is optic neuropathy. We decided to look for neurophysiologic signs of visual damage in patients identified as thinner abusers. Pattern reversal visual evoked potentials was performed on 34...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Polymorphisms which are inherited alterations in the activity of cytochrome P450 1B1 (CYP1B1), catechol O-methyltransferase (COMT), manganese superoxide dismutase (MnSOD) hold the potential to define differences in estrogen metabolism and, thereby, possibly explain inter-individual differences in cancer susc...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2004.10.003
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVE:Lipoprotein(a) [Lp(a)] is an independent cardiovascular risk factor. We present real-life characteristics of patients with increased Lp(a) levels attending a University Lipid Clinic. METHODS:We retrospectively studied patients attending the University of Ioannina Hospital Lipid Clinic with Lp(a) levels ≥30 m...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2020.12.003
更新日期:2020-12-27 00:00:00
abstract::In Mexico, hypercholesterolemia has become a major public health problem particularly in the states of the north of the country and in Mexico City, where a prevalence of 20% has been reported. Schemes of treatment have now been reinforced by the appearance of new cholesterol reducing drugs. The objective of the study ...
journal_title:Archives of medical research
pub_type: 临床试验,杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract:BACKGROUND:Adrenoceptors have been involved in the regulation of hepatocyte proliferation after partial hepatectomy, as well as in primary culture. This report characterizes alpha 1- and beta-adrenoceptor change during the time-course of liver regeneration in adult Wistar Kyoto rats. METHODS:Saturation binding assays ...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-0128(98)00028-1
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVE:To investigate interaction between autophagy and PKC-ε in lipid metabolism of NAFLD cell models. METHODS:HL-7702 cells and SK-HEP-1 cells were cultured in vitro as NAFLD cell models and treated with RAPA to induce autophagy. 3-MA was used to inhibit cell autophagy. And HL-7702 and SK-HEP-1 cell were ordinary...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2018.11.006
更新日期:2018-08-01 00:00:00
abstract::Scorpion venom contains different types of peptides toxic to a variety of organisms whose molecular targets have been described as mainly ion-channels of excitable cells where they cause impairment of function. Based on mouse, cricket, and crustacean bioassays, specific toxins for each group of animals have been found...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-4409(02)00370-3
更新日期:2002-07-01 00:00:00
abstract:BACKGROUND:Although several studies have identified factors associated with bone mineral density (BMD), little research is available on Mexican women. METHODS:A cross-sectional study was conducted in 1,622 female workers between 20 and 80 years of age at the Mexican Social Security Institute (IMSS), an integral part o...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2003.12.001
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND AND AIMS:As a newly discovered B-cell subset, PDCA-1(+) B cells have been shown to participate in the immune clearance of invading pathogens. The prominence of PDCA-1(+) B cell immunity in the pathogenesis of Helicobacter pylori infection prompted us to explore the potential role of this subset in gastric H....
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2016.04.003
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Tumor necrosis factor-alpha (TNF-alpha) is found to play important roles in acute myocardial infarction (AMI). Ventricular arrhythmias arising from AMI are leading causes of sudden cardiac death (SCD). We sought to clarify the effect of TNF-alpha early expression on ventricular arrhythmias in rats with AMI a...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2007.10.004
更新日期:2008-04-01 00:00:00
abstract::At the end of the year 2019, the novel coronavirus (2019-nCoV) was spreading in Wuhan, China, and the outbreak process has a high speed. It was recognized as a pandemic by the World Health Organization (WHO) on 11 March 2020. Coronaviruses are enveloped and single-stranded RNA that have several families including Seve...
journal_title:Archives of medical research
pub_type: 杂志文章,评审
doi:10.1016/j.arcmed.2020.04.022
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:The aim of this study was to provide insight into the interpretation of CK-MB data after major noncardiac surgery. METHODS:Some 3,321 patients who underwent major non-emergent noncardiac procedures (orthopedic 31%, intrathoracic 12%, vascular 22%, other 35%) were studied. All patients had at least two CK sa...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1998-04-01 00:00:00
abstract::The myosin heavy chain gene A, mhcA, from E. histolytica was identified by polymerase chain reaction. There is only one copy of this gene on the ameba genome. The mhcA gene encodes a 6 kb messenger RNA. The predicted protein sequence is homologous to myosin II from both, Dictyostelium discoideum and Acanthamoeba caste...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND:A method is needed to measure parameters of vertigo and disequilibrium. Our objective was to ascertain whether the vestibular autorotation test (VAT) gives numerical data on the vestibular oculomotor reflex (VOR) that are useful for clinical research. METHODS:A VAT was carried out on 17 healthy young volunt...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/s0188-4409(00)00068-0
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:The main objectives in this work were to determine whether the relationship between serum testosterone concentration and electroencephalography (EEG) develop mental change observed in human males is also present in Macaca mulatta and, if so, to determine which frequency bands are involved and which regions c...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:10.1016/j.arcmed.2004.06.003
更新日期:2004-09-01 00:00:00
abstract::The prevalence of antibodies against the repeat epitope of the circumsporozoite protein (cs) of the standard (PV210) and variant (PVK247) strain of Plasmodium vivax was determined by ELISA in 1170 sera from individual residents of seven localities of the Region Huasteca of San Luis Potosi, Mexico. The capture antigens...
journal_title:Archives of medical research
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00