Abstract:
OBJECTIVE:We hypothesized that low presenting systolic blood pressure (SBP) predicted cardioembolic stroke aetiology. DESIGN:Active and passive surveillance were used to identify all ischaemic strokes as part of the Brain Attack Surveillance in Corpus Christi (BASIC) population-based study. Multinomial logistic regression was used to examine the association between stroke subtype and first documented SBP in the medical record. SETTING:Nueces County, TX, USA (313,645 residents in 2000). The community is urban with the majority of the population residing in the city of Corpus Christi. The area is served by seven adult acute care hospitals. PATIENTS:Three hundred and eight cases with completed ischaemic stroke and determined subtype aetiology between January 2000 and December 2002. RESULTS:Lower presenting SBP was associated with stroke subtype (P = 0.001). This association remained significant in the final model adjusted for age and history of coronary artery disease. The odds of cardioembolic versus small vessel occlusion increased by 20% (OR = 1.20, 95% CI: 1.07-1.35) for every 10 mmHg decrease in presenting SBP. Other covariates including race/ethnicity, gender, history of hypertension, and diabetes were neither significant predictors of stroke subtype, nor did they confound the association of SBP and stroke subtype. A 5 year increase in age increased the odds of cardioembolic subtype by 25% (OR = 1.25, 95% CI: 1.07-1.47). CONCLUSIONS:Lower initial SBP and older age at ischaemic stroke presentation were associated with cardioembolic stroke. Suspicion of cardioembolic stroke should be increased in those presenting with low SBP.
journal_name
J Intern Medjournal_title
Journal of internal medicineauthors
Meurer WJ,Sánchez BN,Smith MA,Lisabeth LD,Majersik JJ,Brown DL,Uchino K,Bonikowski FP,Mendizabal JE,Zahuranec DB,Morgenstern LBdoi
10.1111/j.1365-2796.2008.02022.xsubject
Has Abstractpub_date
2009-03-01 00:00:00pages
388-96issue
3eissn
0954-6820issn
1365-2796pii
JIM2022journal_volume
265pub_type
杂志文章,多中心研究abstract::Two hundred consecutive patients with femoral neck fractures (FNF) and 200 controls matched by age, sex, nursing home residency and number of admissions within the last 2 years, were interviewed about recent drug use. The matching criteria were chosen to achieve case and control groups that were comparable with regard...
journal_title:Journal of internal medicine
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journal_title:Journal of internal medicine
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Journal of internal medicine
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journal_title:Journal of internal medicine
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journal_title:Journal of internal medicine
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更新日期:1993-08-01 00:00:00
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更新日期:2014-01-01 00:00:00
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