Predictors for starting depot administration of risperidone in chronic users of antipsychotics.

abstract：OBJECTIVE:The associations between prenatal exposure to antidepressants and preterm delivery and fetal growth restriction are controversial and poorly understood. We studied the relation between antidepressant use and these outcomes. METHODS:Analysis included women with nonmalformed infants interviewed in the Slone Ep...

journal_title：Journal of clinical psychopharmacology

authors： Toh S,Mitchell AA,Louik C,Werler MM,Chambers CD,Hernández-Díaz S

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Despite initial reports of efficacy in bipolar depression, multicenter trials did not show aripiprazole to be better than placebo, possibly because the doses used were too high, leading to lower efficacy and high dropout rates. This study evaluated the effects of low-dose aripiprazole. Extensive clinical exp...

journal_title：Journal of clinical psychopharmacology

authors： Kelly T,Lieberman DZ

更新日期：2017-02-01 00:00:00

abstract：:Zolpidem is an imidazopyridine hypnotic that is biochemically distinct from classic benzodiazepine agonists in that it may be selective for the BZ1 receptor subtype and shows a different pattern of distribution of binding sites. The present study compared the learning, recall, performance, subject-rated and observer-r...

journal_title：Journal of clinical psychopharmacology

authors： Rush CR,Griffiths RR

更新日期：1996-04-01 00:00:00

abstract：:There have been many attempts to find predictors of the therapeutic response to the clomipramine treatment of obsessive-compulsive disorder. The majority of studies have failed to identify such predictors. Possible reasons for this failure include the small sample size of most studies, samples homogeneous with respect...

journal_title：Journal of clinical psychopharmacology

authors： Ackerman DL,Greenland S,Bystritsky A,Morgenstern H,Katz RJ

更新日期：1994-08-01 00:00:00

abstract：:Some of the selective serotonin reuptake inhibitors (SSRI)-induced motor side effects are mediated by stimulating 5-HT2 receptors in the basal ganglia, probably because serotonin inhibits the subsequent neuronal dopamine release. We hypothesized that nefazodone, a serotonin 2 antagonist/reuptake inhibitor (SARI) that ...

journal_title：Journal of clinical psychopharmacology

authors： Avila A,Cardona X,Martin-Baranera M,Maho P,Sastre F,Bello J

更新日期：2003-10-01 00:00:00

abstract：:Plasma and red blood cell levels of haloperidol, thioridazine, and thioridazine's main metabolite mesoridazine were measured in schizophrenic outpatients during treatment with fixed doses of haloperidol or thioridazine for several months. These drug levels were compared to those in schizophrenic inpatients treated wit...

journal_title：Journal of clinical psychopharmacology

authors： Shvartsburd A,Sajadi C,Morton V,Mirabi M,Gordon J,Smith RC

更新日期：1984-08-01 00:00:00

abstract：:Phencyclidine (PCP) abuse has diminished since PCP's intrusion into American culture in the late 1970s. One of its legacies is the assumption that it provokes violent behavior in humans with predictable regularity. This assumption is so accepted that ingestion of the drug both accidentally and knowingly prior to commi...

journal_title：Journal of clinical psychopharmacology

authors： Brecher M,Wang BW,Wong H,Morgan JP

更新日期：1988-12-01 00:00:00

abstract：PURPOSE/BACKGROUND:Extensive research has been conducted comparing the metabolic characteristics of older second-generation antipsychotics (SGAs); minimal data exist comparing the long-term metabolic effects of SGAs approved in the last 10 years. METHODS/PROCEDURES:A retrospective chart review of patients treated with...

journal_title：Journal of clinical psychopharmacology

authors： Greger J,Aladeen T,Lewandowski E,Wojcik R,Westphal E,Rainka M,Capote H

更新日期：2021-01-01 00:00:00

abstract：CONTEXT:Major depressive disorder causes significant morbidity and mortality. Current therapies fail to fully treat both emotional and physical symptoms of major depressive disorder. OBJECTIVE:To evaluate duloxetine, a dual reuptake inhibitor of serotonin and norepinephrine, on improvement of emotional and painful phy...

journal_title：Journal of clinical psychopharmacology

authors： Goldstein DJ,Lu Y,Detke MJ,Wiltse C,Mallinckrodt C,Demitrack MA

更新日期：2004-08-01 00:00:00

abstract：:In a recent study, the authors suggested that tachycardia, dry mouth, and sweating continued to burden patients with panic disorder with agoraphobia who have shown marked and stable response to 6 months of imipramine treatment at the fixed, weight-adjusted dose of 2.25 mg/kg/day. Although sexual dysfunction and weight...

journal_title：Journal of clinical psychopharmacology

authors： Mavissakalian M,Perel J,Guo S

更新日期：2002-04-01 00:00:00

abstract：:Successful discontinuation of therapeutic drugs requires patients to negotiate two potentially difficult phases. First, they must complete the drug discontinuation procedure itself, which may entail coping with rebound and withdrawal symptoms as well as anxiety due to stopping a treatment on which they depend psycholo...

journal_title：Journal of clinical psychopharmacology

authors： Spiegel DA

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Olanzapine, a commonly used second-generation antipsychotic, causes severe metabolic adverse effects, such as elevated blood glucose and insulin resistance (IR). Previous studies have proposed that overexpression of CD36, GGPPS, PTP-1B, GRK2, and adipose triglyceride lipase may contribute to the development ...

journal_title：Journal of clinical psychopharmacology

authors： Yang N,Li S,Liu S,Lv Y,Yu L,Deng Y,Li H,Fang M,Huo Y,Li W,Peng S

更新日期：2019-05-01 00:00:00

abstract：:Two cases of mania following the discontinuation of treatment with isocarboxazid are described. Although this phenomenon has been reported by several investigators to occur after cessation of tricyclic antidepressant therapy, there exists only one isolated report of hypomania after discontinuation of monoamine oxidase...

journal_title：Journal of clinical psychopharmacology

authors： Rothschild AJ

更新日期：1985-12-01 00:00:00

abstract：:The objective of this study was to assemble expert clinical experience and judgment regarding the treatment of panic disorder in a systematic, quantitative manner, particularly with respect to changes during the past 5 years. A panel of 73 internationally recognized experts in the field of pharmacotherapy of anxiety a...

journal_title：Journal of clinical psychopharmacology

authors： Uhlenhuth EH,Balter MB,Ban TA,Yang K

更新日期：1998-12-01 00:00:00

abstract：:Paroxetine is a novel phenylpiperidine antidepressant agent that acts as a potent and selective inhibitor of serotonin reuptake. We report results of a 6-week, randomized, double-blind, multicenter study comparing paroxetine and fluoxetine in the treatment of major depression. One hundred seventy-eight inpatients, who...

journal_title：Journal of clinical psychopharmacology

authors： Tignol J

更新日期：1993-12-01 00:00:00

abstract：:Idazoxan, a selective alpha 2-adrenergic antagonist, was added to stable doses of fluphenazine treatment in six patients with schizophrenia who participated in a double-blind, placebo-controlled pharmacologic study. Compared with fluphenazine alone, combining idazoxan (mean dose, 120 mg/day) with fluphenazine (mean do...

journal_title：Journal of clinical psychopharmacology

authors： Litman RE,Hong WW,Weissman EM,Su TP,Potter WZ,Pickar D

更新日期：1993-08-01 00:00:00

abstract：:Patients with obsessive-compulsive disorder (OCD) have been shown to be preferentially responsive to serotonin (5-HT) uptake-inhibiting antidepressants including clomipramine, fluoxetine, fluvoxamine, and sertraline. The nontricyclic antidepressant, trazodone, also possesses serotonin reuptake inhibiting properties an...

journal_title：Journal of clinical psychopharmacology

authors： Pigott TA,L'Heureux F,Rubenstein CS,Bernstein SE,Hill JL,Murphy DL

更新日期：1992-06-01 00:00:00

abstract：:There have been several case reports of improvement in tardive dyskinesia (TD) after treatment with calcium-blocking agents. We have conducted prior single-blind (rater-blind) studies of verapamil and diltiazem and found a statistically significant improvement in TD with verapamil, and a small improvement that did not...

journal_title：Journal of clinical psychopharmacology

authors： Duncan E,Adler L,Angrist B,Rotrosen J

更新日期：1990-12-01 00:00:00

abstract：:The assessment of adverse effects of psychiatric medications is important in clinical and research settings because they are often associated with medication discontinuation, symptom exacerbation, and reduced quality of life. Currently available assessment tools are either limited with regard to the number and variety...

journal_title：Journal of clinical psychopharmacology

authors： Nugent KL,Spahr E,Toroney J,Mojtabai R,Nettles C,Turner LW,Fenton A,Spivak A,Cullen BA,Everett A,Eaton WW

更新日期：2015-06-01 00:00:00

abstract：:The aims of this study were to examine whether pindolol, a serotonin (5-hydroxytryptamine [5-HT])-1A receptor antagonist, and mianserin, a 5-HT2A/C and alpha2-adrenoceptor (alpha2-AR) antagonist, may augment the clinical efficacy of fluoxetine, a selective serotonin reuptake inhibitor, and shorten the latency of onset...

journal_title：Journal of clinical psychopharmacology

authors： Maes M,Libbrecht I,van Hunsel F,Campens D,Meltzer HY

更新日期：1999-04-01 00:00:00

abstract：:Phenomenological, physiological, biochemical, and receptor binding measures are useful as dependent variables in affective disorders research. Abnormalities of these measures can result from up-regulation and supersensitivity of cholinergic systems and disturbances of cholinergic-monoaminergic interaction. These devia...

journal_title：Journal of clinical psychopharmacology

authors： Dilsaver SC

更新日期：1986-04-01 00:00:00

abstract：:Increasing attention is being paid to the development and dissemination of effective pharmacotherapies for the treatment of alcohol and other drug dependence. However, numerous structural and philosophical barriers impede the widespread adoption of these treatment approaches in everyday clinical practice. Research is ...

journal_title：Journal of clinical psychopharmacology

authors： Ducharme LJ,Knudsen HK,Roman PM

更新日期：2006-12-01 00:00:00

abstract：:We compared acute effects of single intravenous administrations of metoclopramide (40 mg) and placebo in a double-blind crossover study involving 81 patients with tardive dyskinesia. Metoclopramide produced significantly greater reduction in mean total Abnormal Involuntary Movement Scale score as well as in ratings fo...

journal_title：Journal of clinical psychopharmacology

authors： Doongaji DR,Jeste DV,Jape NM,Sheth AS,Apte JS,Vahia VN,Desai AB,Parikh MD,Rathi LG,Ghandi MH,Parikh RM,Thatte S,Bharadwaj J

更新日期：1982-12-01 00:00:00

abstract：:Depression is a common disorder in pregnancy and associated with adverse effects for both mother and neonate. Pharmacological treatment and prevention options include mirtazapine. In a series of 56 cases, we investigated neonatal outcome after intrauterine exposure to mirtazapine and exposure through lactation in the ...

journal_title：Journal of clinical psychopharmacology

authors： Smit M,Wennink H,Heres M,Dolman KM,Honig A

更新日期：2015-04-01 00:00:00

abstract：:Over the past 10 years, knowledge gained about the pharmacokinetic profiles of valproate and carbamazepine has increased the clinical effectiveness of their use. Much of the information has been gained through their use as successful antiepileptic medications. As these agents begin to play an increasing role as mood-s...

journal_title：Journal of clinical psychopharmacology

authors： Wilder BJ

更新日期：1992-02-01 00:00:00

abstract：:The measurement of plasma clozapine concentrations is useful in assessing compliance, optimizing therapy, and minimizing toxicity. We measured plasma clozapine and norclozapine (N-desmethylclozapine) concentrations in samples from 3782 patients (2648 male, 1127 female). No clozapine was detected in 291 samples (227 pa...

journal_title：Journal of clinical psychopharmacology

authors： Rostami-Hodjegan A,Amin AM,Spencer EP,Lennard MS,Tucker GT,Flanagan RJ

更新日期：2004-02-01 00:00:00

abstract：:Methamphetamine has become a major public health issue globally, particularly in the United States. Despite this, no effective pharmacotherapy for methamphetamine abuse has been developed to date. This 6-week, open-label pilot clinical trial examined the safety and tolerability of modafinil up to 400 mg/d in 8 methamp...

journal_title：Journal of clinical psychopharmacology

authors： McGaugh J,Mancino MJ,Feldman Z,Chopra MP,Gentry WB,Cargile C,Oliveto A

更新日期：2009-10-01 00:00:00

abstract：AIMS:The aim of this study was the evaluation of the possible relationship between pharmacokinetics and the safety of aripiprazole as well as its influence on blood pressure (BP), heart rate (HR), and corrected QT (QTc) interval. METHODS:The study population comprised 157 healthy volunteers from 6 bioequivalence clini...

journal_title：Journal of clinical psychopharmacology

authors： Belmonte C,Ochoa D,Román M,Cabaleiro T,Talegón M,Sánchez-Rojas SD,Abad-Santos F

更新日期：2016-12-01 00:00:00

abstract：:The objective of this study was to investigate the efficacy of pirenzepine in the treatment of clozapine-induced hypersalivation. Pirenzepine is reported to counteract hypersalivation by its selective antagonistic activity on the M4-muscarinic receptor, which is stimulated by clozapine. Twenty patients with clozapine-...

journal_title：Journal of clinical psychopharmacology

authors： Bai YM,Lin CC,Chen JY,Liu WC

更新日期：2001-12-01 00:00:00

abstract：:The ability of the Hamilton Rating Scale for Anxiety, the Hamilton Rating Scale for Depression, and 50 items from the self-rated Hopkins Symptom Checklist to discriminate generalized anxiety disorder from major depressive disorder was examined for over 3,000 patients entering studies in three drug development projects...

journal_title：Journal of clinical psychopharmacology

authors： Copp JE,Schwiderski UE,Robinson DS

更新日期：1990-06-01 00:00:00