Abstract:
INTRODUCTION:Bipolar mood disorder carries a serious suicide risk. Panic disorder, which also confers an independent risk of suicide and psychiatric comorbidity, in general has been found to amplify suicidality in mood-disordered patients. This article assesses the available literature on how panic and suicide relate to each other in bipolar mood-disordered patients. METHODS:We conducted a search on Medline and PsycINFO using the keywords "anxiety", "attempted suicide", "completed suicide", "mortality", "self-harm" in combination with "bipolar", "manic depression" and "panic". Twenty-four articles were included in the evaluation. RESULTS:14 papers support increased risk, 9 papers do not support increased risk, and 3 papers are inconclusive. CONCLUSIONS:The presence of comorbid panic disorder in individuals with bipolar disorder may confer an increased risk of suicide risk. Some papers' reviewed have conflicting conclusions but the majority of papers support an increased risk. This is consistent with a recent (2008) literature review supporting increased risk of suicide in bipolar patients with comorbid anxiety disorders. Future research should study specific bipolar subgroups, focus on anxiety and panic symptoms rather than diagnosis, and look at the role of specific pharmacological treatment in patients with comorbid mood and anxiety disorders.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Kilbane EJ,Gokbayrak NS,Galynker I,Cohen L,Tross Sdoi
10.1016/j.jad.2008.09.014subject
Has Abstractpub_date
2009-05-01 00:00:00pages
1-10issue
1-2eissn
0165-0327issn
1573-2517pii
S0165-0327(08)00374-1journal_volume
115pub_type
杂志文章,评审abstract:OBJECTIVES:Several studies have recently been conducted that have explored the benefits of psychological interventions in reducing symptomatology or improving outcomes in young people at-risk of developing bipolar disorder. The aim of this review was to explore if such interventions reduce current psychiatric symptoms ...
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abstract:BACKGROUND:The effect of disasters on suicidality is not known. We aimed to retrospectively determine the cumulative incidence of suicidal ideation during the 3 years after the Great East Japan Earthquake among residents in temporary housing without prior suicidal ideation, as compared to the general population. Moreov...
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pub_type: 杂志文章,随机对照试验
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更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Brain-derived neurotrophic factor (BDNF) is a member of the nerve growth factor family and plays a critical role in growth, differentiation, maintenance and synaptic plasticity of neuronal systems. Previous studies have demonstrated lower serum BDNF concentrations in major depressive disorder (MDD), with con...
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journal_title:Journal of affective disorders
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journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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更新日期:2014-09-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析,评审
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更新日期:2017-08-01 00:00:00
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doi:10.1016/j.jad.2006.04.011
更新日期:2006-08-01 00:00:00
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更新日期:2020-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-06-01 00:00:00
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更新日期:2020-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:1996-06-20 00:00:00
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doi:10.1016/j.jad.2019.04.054
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pub_type: 杂志文章,meta分析
doi:10.1016/j.jad.2018.08.067
更新日期:2018-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2002-11-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2012-12-10 00:00:00
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更新日期:2019-10-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2006-07-01 00:00:00
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更新日期:1986-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jad.2010.07.026
更新日期:2011-02-01 00:00:00
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pub_type: 杂志文章
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更新日期:1991-10-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.07.030
更新日期:2013-04-25 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2015-03-15 00:00:00
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pub_type: 杂志文章
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更新日期:2016-01-01 00:00:00
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更新日期:2019-03-01 00:00:00