Common factor 1 is a transcriptional activator which binds in the c-myc promoter, the skeletal alpha-actin promoter, and the immunoglobulin heavy-chain enhancer.

Abstract:

:Ubiquitously expressed transcription factors play an integral role in establishing and regulating patterns of gene transcription. Common factor 1 (CF1) is a ubiquitously expressed DNA-binding protein previously identified in our laboratory. We show here that CF1 recognizes sites in several diverse transcription elements, and we demonstrate the ability of the c-myc CF1 site to activate transcription of a basal promoter in both B cells and fibroblasts.

journal_name

Mol Cell Biol

authors

Riggs KJ,Merrell KT,Wilson G,Calame K

doi

10.1128/mcb.11.3.1765

subject

Has Abstract

pub_date

1991-03-01 00:00:00

pages

1765-9

issue

3

eissn

0270-7306

issn

1098-5549

journal_volume

11

pub_type

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