Plasma adiponectin and resistin levels as predictors of mortality in patients with acute myocardial infarction: data from infarction prognosis study registry.


BACKGROUND:Adiponectin and resistin, which have counteracting effects, are suggested to be associated with inflammation and atherosclerosis. The relationship between their levels and prognosis in high risk patients is, however, still unclear. The aim of this study was to evaluate the prognostic values of these adipokines in patients with acute myocardial infarction (MI). METHODS:Adiponectin and resistin levels were measured at acute phase of MI in 397 consecutive patients. All patients were followed-up for the occurrence of all-cause and cardiovascular mortalities. Predictors for all-cause and cardiovascular mortalities were analyzed by Cox proportional hazard model. RESULTS:During the mean follow-up period of 12 months, 28 (7.1%) patients died. Unadjusted all-cause mortality rate was significantly higher in patients with high tertiles of adiponectin (P=0.002) and resistin (P=0.002) levels. After controlling of clinical and laboratory variables, age [95% confidence interval (CI): 1.20-2.83, P=0.006], adiponectin (95% CI: 1.01-1.22, P=0.040), resistin (95% CI: 1.06-2.33, P=0.025), and statin use (95% CI: 0.15-0.83, P=0.017) were found to be independent predictors of all-cause mortality. For cardiovascular mortality, only age (95% CI: 1.33-3.25, P=0.001) and renal insufficiency (95% CI: 1.52-12.22, P=0.006) were independent predictors. CONCLUSION:High plasma adiponectin and resistin levels were predictors for all-cause mortality independent of other risk factors in patients with acute MI. These results confirmed and extended the positive correlations between these adipokines and mortality to a population consisting exclusively of MI.


Coron Artery Dis


Coronary artery disease


Lee SH,Ha JW,Kim JS,Choi EY,Park S,Kang SM,Choi D,Jang Y,Chung N




Has Abstract


2009-01-01 00:00:00












  • Variations in lymphocyte activation during exercise testing in patients with coronary artery disease.

    abstract:BACKGROUND:Several studies have shown that strenuous exercise induces changes in the immune system. Soluble interleukin-2 receptor (sIL-2R) is a marker of immune system activation and is known to increase in association with cardiac disease. The aim of the present study was to assess sIL-2R levels in patients with coro...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Zafrir N,Shohat B,Ben-Gal T,Solodky A,Sulkes J,Battler A

    更新日期:2004-06-01 00:00:00

  • Preconditioning effects of adenosine in patients with severe coronary artery disease but preserved coronary flow reserve.

    abstract:BACKGROUND:Adenosine plays a key role in different protective and adaptive responses to ischemia and has been suggested to induce ischemic preconditioning. AIM:To investigate whether a low-dose adenosine infusion reduces the ischemic burden induced by pharmacological stress without affecting the coronary flow reserve ...

    journal_title:Coronary artery disease

    pub_type: 杂志文章,随机对照试验


    authors: Sadigh B,Shahgaldi K,Sylvén C,Quintana M,Winter R

    更新日期:2009-08-01 00:00:00

  • The risk of stroke in patients with acute myocardial infarction treated invasively.

    abstract:BACKGROUND:To assess the incidence, clinical significance, and independent risk factors of stroke in patients with acute myocardial infarction (AMI) treated invasively. MATERIALS AND METHODS:We analyzed 2520 consecutive patients with AMI admitted between 2003 and 2007. Data on long-term follow-up were screened to iden...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Podolecki TS,Lenarczyk RK,Kowalczyk JP,Mazurek MH,Swiątkowski AM,Chodór PK,Pruszkowska-Skrzep PI,Sędkowska AA,Poloński L,Kalarus ZF

    更新日期:2012-01-01 00:00:00

  • Early repolarization in the inferolateral leads predicts the presence of vasospastic angina: a novel predictor in patients with resting angina.

    abstract:BACKGROUND:An association between early repolarization and ventricular fibrillation has recently been reported in patients with vasospastic angina (VSA). However, no studies have clarified whether the presence of early repolarization can predict VSA. METHODS:Participants comprised 286 patients (136 males) with clinica...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Ikeda H,Hasegawa K,Uzui H,Fukuoka Y,Shiomi Y,Tama N,Miyazaki S,Ishida K,Tada H

    更新日期:2020-11-13 00:00:00

  • Predictive value of endothelial function by noninvasive peripheral arterial tonometry for coronary artery disease.

    abstract:BACKGROUND:Endothelial dysfunction is a key step in the initiation and progression of atherosclerosis and subsequent cardiovascular complications. We examined whether peripheral endothelial function, as assessed by fingertip reactive hyperemia-peripheral arterial tonometry (RH-PAT), can provide additional clinical valu...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Matsuzawa Y,Li J,Aoki T,Guddeti RR,Kwon TG,Cilluffo R,Widmer RJ,Gulati R,Lennon RJ,Lerman LO,Lerman A

    更新日期:2015-05-01 00:00:00

  • Circulating T-lymphocyte activation in patients with variant angina.

    abstract:BACKGROUND:Both experimental and pathological studies suggest that immune response and inflammation may play an important role in the pathogenesis of coronary spasm. DESIGN:To elucidate the role of systemic immune and inflammatory responses in the pathogenesis of coronary spasm, we studied circulating T-lymphocyte act...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Terashima M,Akita H,Kanazawa K,Shiga N,Matsuda Y,Hirata K,Kawashima S,Yokoyama M

    更新日期:2002-05-01 00:00:00

  • Myocardial Doppler tissue velocity improves following myocardial gene therapy with VEGF-A165 plasmid in patients with inoperable angina pectoris.

    abstract:BACKGROUND:Myocardial tissue velocity and perfusion were studied in patients with severe angina pectoris following gene therapy by intramyocardial injection of phVEGF-A165 via thoracotomy. Plasma concentrations of VEGF-A increased postoperatively. Two months after treatment anginal status and myocardial tissue velocity...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Sylvén C,Sarkar N,Rück A,Drvota V,Hassan SY,Lind B,Nygren A,Källner Q,Blomberg P,van der Linden J,Lindblom D,Brodin LA,Islam KB

    更新日期:2001-05-01 00:00:00

  • Safety and efficacy of the NovaCross microcatheter in facilitating crossing of chronic total occlusion coronary lesions: a multicenter, single-arm clinical trial.

    abstract:BACKGROUND:The aim of this study was to evaluate the safety and efficacy of the novel NovaCross microcatheter system in patients with ischemic heart disease due to coronary chronic total occlusions (CTO). METHODS:A total of 191 subjects between the ages of 25-80 years were recruited in 10 investigational sites. Each s...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Walsh SJ,Dudek D,Bryniarski L,Nicholson W,Karmpaliotis D,Uretsky B,McEntegart M,Assali A,Knaapen P,Kornowski R,Spratt JC,Goodwin M,Hanratty CG

    更新日期:2020-11-01 00:00:00

  • Drug-coated balloon treatment for nonsmall de-novo coronary artery disease: angiographic and clinical outcomes.

    abstract:OBJECTIVES:Although drug-coated balloons (DCBs) are established for de-novo lesions in small coronary arteries, the impact of DCB treatment according to the reference vessel diameter (RVD) remains poorly defined. This study aimed to evaluate the angiographic and long-term clinical outcomes of DCB treatment for de-novo ...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Her AY,Yuan SL,Jun EJ,Bhak Y,Kim MH,Garg S,Kim YH,Kun L,Hui L,Zhi W,Hao J,Zhentao S,Qiang T,Shin ES

    更新日期:2021-01-18 00:00:00

  • Association of the serum apolipoprotein levels with the occurrence of coronary vasospasm.

    abstract:BACKGROUND:The relationship between the serum levels of atherosclerosis-related apolipoprotein (apo) and the risk of coronary spastic angina remains unknown. METHODS AND RESULTS:This study consists of 111 patients who were admitted to our facility with the chief complaint of chest pain, in whom coronary angiography sh...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Tani S,Nagao K,Kawamorita T,Hirayama A

    更新日期:2011-05-01 00:00:00

  • Acute right ventricular infarction: clinical spectrum, results of reperfusion therapy and short-term prognosis.

    abstract:BACKGROUND:The role of thrombolytic therapy (TT) and percutaneous coronary interventions (PCIs) in subgroups of patients with right ventricular infarction (RVI) has not been evaluated. METHODS AND RESULTS:We risk-stratified 302 patients with RVI into three subsets upon admission. Class A (n=197) comprised patients wit...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Lupi-Herrera E,Lasses LA,Cosio-Aranda J,Chuquiure-Valenzuela E,Martínez-Sánchez C,Ortiz P,González-Pacheco H,Juárez-Herrera U,Rodriguez Mdel C,Vargas-Barrón J,Martínez-Rios MA

    更新日期:2002-02-01 00:00:00

  • High-dose diltiazem prevents migration and proliferation of vascular smooth muscle cells in various in-vitro models of human coronary restenosis.

    abstract:BACKGROUND:Restenosis after coronary angioplasty is considered to be caused mainly by increased migration and proliferation of smooth muscle cells (SMC). The concept of local, site-specific delivery of pharmacologic therapies has opened the door for new, high-dose drug regimes. METHODS AND RESULTS:SMC were isolated by...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Voisard R,Koschnick S,Baur R,Vogel U,Mattfeldt T,Hemmer W,Hannekum A,Höher M,Hombach V

    更新日期:1997-03-01 00:00:00

  • The phytoestrogens Genistein and Daidzein, and 17 beta-estradiol inhibit development of neointima in aortas from male and female rabbits in vitro after injury.

    abstract:BACKGROUND:17 beta-Estradiol and phytoestrogens are known to have beneficial effects on the cardiovascular systems of women. The exact mechanisms for how estrogens and phytoestrogens influence the cardiovascular system are not yet understood in detail. OBJECTIVE:The objective of this study was to investigate whether 1...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Finking G,Wohlfrom M,Lenz C,Wolkenhauer M,Eberle C,Hanke H

    更新日期:1999-12-01 00:00:00

  • Quantitative assessment of free-radical generation during ischemia and reperfusion in the isolated rabbit heart.

    abstract:BACKGROUND:Several investigators have indirectly implicated oxygen free radicals in reperfusion injury following ischemia in the isolated rabbit heart. METHODS:A quantitative assessment of free-radical production during ischemia and reperfusion was made using electron paramagnetic resonance (EPR) spectroscopy. Serial ...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Premaratne S,Limm W,Mugiishi MM,Piette LH,McNamara JJ

    更新日期:1993-12-01 00:00:00

  • Long-term events after physician-referred initial tests by myocardial perfusion imaging or computed tomography coronary angiography in patients with suspected coronary artery disease.

    abstract:BACKGROUND:The effects of initial tests on long-term events have been unknown. PATIENTS AND METHODS:In this observational retrospective study, we analyzed the effects of initial noninvasive tests by myocardial perfusion imaging (MPI) and computed tomography angiography (CTA) on long-term major adverse cardiac events (...

    journal_title:Coronary artery disease

    pub_type: 杂志文章,多中心研究


    authors: Naya M,Uemura Y,Matsumoto N,Momose M,Kato T,Hida S,Yamauchi T,Nakajima T,Suzuki E,Tamaki N,J-COMPASS Extended Follow-Up Study Group.

    更新日期:2018-11-01 00:00:00

  • Comparison of a low-molecular-weight heparin (nadroparin calcium) and unfractionated heparin as adjunct to coronary thrombolysis with alteplase and aspirin in dogs.

    abstract:BACKGROUND:Low-molecular-weight heparins may have a higher benefit to risk ratio than unfractionated heparin in preventing perioperative thrombosis. The antithrombotic effects of low-molecular-weight heparins, given as adjunctive therapy to alteplase and aspirin, have not previously been compared with those of unfracti...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Jun L,Arnout J,Vanhove P,Dol F,Lormeau JC,Herbert JM,Collen D,Van de Werf F

    更新日期:1995-03-01 00:00:00

  • The antiarrhythmic effect and clinical consequences of ischemic preconditioning.

    abstract::Potentially hazardous short ischemic episodes increase the tolerance of myocardium to ischemia paradoxically. This condition decreases the infarct area markedly caused by a longer duration of coronary occlusion. This phenomenon is known as 'ischemic preconditioning' and its powerful cardioprotective effect has been sh...

    journal_title:Coronary artery disease

    pub_type: 杂志文章,评审


    authors: Evrengul H,Seleci D,Tanriverdi H,Kaftan A

    更新日期:2006-05-01 00:00:00

  • One-year outcome following coronary angiography in elderly patients with non-ST elevation myocardial infarction: real-world data from the Acute Coronary Syndromes Israeli Survey (ACSIS).

    abstract:OBJECTIVES:We aimed to evaluate the management and outcomes of patients of the octogenarian age group with non-ST elevation myocardial infarction (NSTEMI) in a real-world setting. METHODS:The risk of 30-day and 1-year mortality by age and the time of coronary angiography [categorized as early (≤48 h of admission) and ...

    journal_title:Coronary artery disease

    pub_type: 杂志文章,多中心研究


    authors: Buber J,Goldenberg I,Kimron L,Guetta V

    更新日期:2013-03-01 00:00:00

  • Coronary artery calcium score: pivotal role as a predictor for detecting coronary artery disease in symptomatic patients.

    abstract::Chest pain and dyspnea are common presentations for symptomatic individuals with suspected coronary artery disease (CAD) in the primary care office and cardiology clinics. However, it is imperative to properly diagnose who should undergo further evaluation for cardiac etiologies of chest pain, with either noninvasive ...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Cherukuri L,Birudaraju D,Budoff MJ

    更新日期:2021-01-18 00:00:00

  • Reduced low-frequency heart rate variability relates to greater intimal-medial thickness of the carotid wall in two samples.

    abstract:INTRODUCTION:We investigated the relationship between heart rate variability and preclinical carotid intima-media thickening, a putative index of atherosclerosis. METHODS:A sample of 350 men and women (mean age 56.8 years) selected for the presence or absence of untreated hypertension was assessed for heart rate varia...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Gautier C,Stine L,Jennings JR,Sutton-Tyrrell K,Muldoon MB,Kamarck TW,Kaplan GA,Salonen J,Manuck SB

    更新日期:2007-03-01 00:00:00

  • Circulating adhesion molecules and severity of coronary atherosclerosis.

    abstract:BACKGROUND:Circulating leukocytes are recruited at atherosclerotic sites through a family of adhesion molecules. Circulating forms of adhesion molecules in peripheral blood can be quantified now. OBJECTIVE:To evaluate the relationship between circulating adhesion molecules and severity of coronary atherosclerosis. ME...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Oishi Y,Wakatsuki T,Nishikado A,Oki T,Ito S

    更新日期:2000-02-01 00:00:00

  • Incidence, predictors, and 30-day outcomes of new-onset atrial fibrillation after primary percutaneous coronary intervention: insight into the RISK-PCI trial.

    abstract:OBJECTIVES:Limited data exist about the prognostic significance of new-onset atrial fibrillation (AF) after contemporary primary percutaneous coronary intervention (pPCI). The objective of this study was to identify the incidence and predictors of new-onset AF and associated adverse 30-day outcomes in AF patients who u...

    journal_title:Coronary artery disease

    pub_type: 临床试验,杂志文章


    authors: Mrdovic I,Savic L,Krljanac G,Perunicic J,Asanin M,Lasica R,Antonijevic N,Kocev N,Marinkovic J,Vasiljevic Z,Ostojic M

    更新日期:2012-01-01 00:00:00

  • Statins and myocardial hypertrophy.

    abstract::Cardiac hypertrophy is a physiological adaptive response by the heart to pressure overload. However, after prolonged periods, this initial adaptive response becomes maladaptive, leading to increased mortality and morbidity from heart failure. Recently, 3-hydroxyl-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibit...

    journal_title:Coronary artery disease

    pub_type: 杂志文章,评审


    authors: Nakagami H,Liao JK

    更新日期:2004-08-01 00:00:00

  • Role of activation-dependent platelet membrane glycoproteins in development of subacute occlusive coronary stent thrombosis.

    abstract:BACKGROUND:Platelets have an important role in coronary thrombosis. METHODS:We studied 151 consecutive patients undergoing implantation of Palmaz-Schatz stents because of suboptimal results after coronary balloon angioplasty treated by intense anticoagulation. Surface exposure of the constitutively expressed glycoprot...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Gawaz M,Neumann FJ,Ott I,May A,Rüdiger S,Schömig A

    更新日期:1997-03-01 00:00:00

  • New carotid plaque, but not the progression of intima-media thickness, predicts the progression of high-risk coronary plaque.

    abstract:BACKGROUND:Carotid intima-media thickness (CIMT) is regarded as a controversial risk marker for cardiovascular disease (CVD). We aimed to evaluate the role of CIMT and carotid plaque progression as predictors for the progression of coronary plaque and compositions. METHODS:In the Garlic 4 study, asymptomatic patients ...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Chao CJ,Lakshmanan S,Ceponiene I,Luo Y,Nakanishi R,Nezarat N,Kanisawa M,Budoff MJ

    更新日期:2021-01-06 00:00:00

  • Poor coronary collateral circulation is associated with higher concentrations of soluble adhesion molecules in patients with single-vessel disease.

    abstract:OBJECTIVE:As the endothelium and inflammatory cells play a crucial role in the development of collaterals after a sudden or slowly progressing stenosis of coronary arteries, the levels of soluble endothelial adhesion molecules (CAMs) including vascular cell adhesion molecule (VCAM-1) intercellular adhesion molecule-1 (...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Guray U,Erbay AR,Guray Y,Yilmaz MB,Boyaci AA,Sasmaz H,Korkmaz S,Kutuk E

    更新日期:2004-11-01 00:00:00

  • Effects of exercise training on mortality in patients with coronary heart disease.

    abstract::Endothelial dysfunction not only precedes the development of significant coronary artery stenosis, it has also been identified as a general phenomenon predicting future cardiovascular events in patients who are at risk. As regular physical activity as a part of a multifactorial intervention has been shown to affect sy...

    journal_title:Coronary artery disease

    pub_type: 杂志文章,评审


    authors: Erbs S,Linke A,Hambrecht R

    更新日期:2006-05-01 00:00:00

  • Effects of electrode size and spacing on the resolution of intracardiac electrograms.

    abstract:BACKGROUND:Electrogram fractionation can result when multiple groups of cardiac cells are excited asynchronously within the recording region of a mapping electrode. The spatial resolution of an electrode thus plays an important role in mapping complex rhythms. METHODS:We used a computational model, validated against e...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Stinnett-Donnelly JM,Thompson N,Habel N,Petrov-Kondratov V,Correa de Sa DD,Bates JH,Spector PS

    更新日期:2012-03-01 00:00:00

  • Predictors of 30-day and 1-year mortality after primary percutaneous coronary intervention for ST-elevation myocardial infarction.

    abstract:OBJECTIVE:Predictors of 30-day mortality may differ from predictors of mortality at 1 year among 30-day survivors of ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). We aimed to evaluate the predictors of 30-day and 1-year mortality in unselected patients with ST...

    journal_title:Coronary artery disease

    pub_type: 杂志文章


    authors: Rasoul S,Ottervanger JP,de Boer MJ,Dambrink JH,Hoorntje JC,Marcel Gosselink AT,Zijlstra F,Suryapranata H,van 't Hof AW,Zwolle Myocardial Infarction Study Group.

    更新日期:2009-09-01 00:00:00

  • Long-term clinical impact of polymer-free sirolimus-eluting stents in unselected patients.

    abstract:OBJECTIVES:The long-term clinical impact of polymer-free sirolimus-eluting stents (PF-SES) in unselected patients undergoing percutaneous coronary intervention (PCI) still remains poorly investigated. We studied the long-term clinical impact of PF-SES in a large cohort of unselected patients receiving PCI therapy at tw...

    journal_title:Coronary artery disease

    pub_type: 杂志文章,多中心研究


    authors: Sinha N,Rai H,Cassese S,Kumar S,Kapoor A,Kastrati A

    更新日期:2016-08-01 00:00:00