Ion channels: from conductance to structure.

Abstract:

:In this perspective I tell the story (albeit a clearly abridged version) of how our knowledge of ion conduction through ion channels has evolved from a purely electrical concept to a structural dynamics view of ions interacting with a membrane protein. Our progress in this field has shown steady growth over the years but has also been interspersed with sudden jumps of discovery. These leaps have normally been associated with the introduction of a new technical advance or the development of a new biological preparation; therefore, it is quite certain that we have not seen them all.

journal_name

Neuron

journal_title

Neuron

authors

Bezanilla F

doi

10.1016/j.neuron.2008.10.035

subject

Has Abstract

pub_date

2008-11-06 00:00:00

pages

456-68

issue

3

eissn

0896-6273

issn

1097-4199

pii

S0896-6273(08)00900-8

journal_volume

60

pub_type

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