Hetero-Diels-Alder reaction of 1,3-bis(trimethylsilyloxy)-1,3-butadienes with arylsulfonylcyanides. Synthesis and antimicrobial activity of 4-hydroxy-2-(arylsulfonyl)pyridines.

Abstract:

:Hetero-Diels-Alder reactions of 1,3-bis(silyloxy)-1,3-butadienes with arylsulfonylcyanides afforded a variety of 4-hydroxy-2-(arylsulfonyl)pyridines. Several derivatives show antimicrobial activity against Gram-positive bacteria.

journal_name

Bioorg Med Chem

authors

Hussain I,Yawer MA,Lalk M,Lindequist U,Villinger A,Fischer C,Langer P

doi

10.1016/j.bmc.2008.10.033

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

9898-903

issue

23

eissn

0968-0896

issn

1464-3391

pii

S0968-0896(08)00985-1

journal_volume

16

pub_type

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