Abstract:
:A 30-year Memorial Hospital experience with 146 patients with malignant mixed tumor is reviewed. These comprised 5% of 2,743 patients who were treated for salivary neoplasms from 1939 through 1968. The tumors arose in the parotid gland in 108 patients, submaxillary gland in 23 patients, mucus or so-called minor salivary glands in 16 patients, and sublingual gland in one. In terms of our total experience, 11% of all submaxillary tumors proved to be of the malignant mixed variety as compared to 6% of parotid tumors and 3% of minor salivary tumors, respectively. Seventy-one patients (48%) had previously received therapy elsewhere. Results of treatment are presented and the factors which influenced the results are discussed.
journal_name
Cancerjournal_title
Cancerauthors
Spiro RH,Huvos AG,Strong EWdoi
10.1002/1097-0142(197702)39:2<388::aid-cncr2820390subject
Has Abstractpub_date
1977-02-01 00:00:00pages
388-96issue
2eissn
0008-543Xissn
1097-0142journal_volume
39pub_type
杂志文章相关文献
CANCER文献大全abstract::Thirty-six patients were evaluated between 1965 and 1983 for glioma of the optic nerves and/or chiasm. Median follow-up was 10.2 years. Pathologic verification was obtained in 32 patients. Tumor initially confined to the optic nerve recurred in one of five patients after complete resection. The actuarial survival for ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19880215)61:4<635::aid-cncr28206
更新日期:1988-02-15 00:00:00
abstract:BACKGROUND:Constitutional or somatic mosaic epimutations are increasingly recognized as a mechanism of gene dysregulation resulting in cancer susceptibility. Beckwith-Wiedemann syndrome is the cancer predisposition syndrome most commonly associated with epimutation and is extremely variable in its phenotypic presentati...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.32907
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Current cervical cancer screening approaches are based on cytology supplemented by human papillomavirus (HPV) testing in some settings. Whereas cytology is laborious and depends on the cytologists' experience, HPV testing has limited specificity when it is used to detect high-grade lesions. A dichotomous tes...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.22247
更新日期:2006-11-01 00:00:00
abstract::Clinical and laboratory data, histologic, electron microscopic and immunocytochemical findings of the tumors of eight patients suffering from Cushing's syndrome and of one patient with hypercalcemia are described. The unlabeled antibody enzyme method was used for the detection of insulin, glucagon, somatostatin, pancr...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19811101)48:9<2029::aid-cncr2820
更新日期:1981-11-01 00:00:00
abstract:BACKGROUND:Nonsteroidal antiinflammatory drugs (NSAIDs) inhibit the development of lung tumors in experimental animals. To the authors' knowledge there are little data regarding whether regular use of NSAIDs reduces the risk of developing lung carcinoma in humans. METHODS:The association between lung carcinoma risk an...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11242
更新日期:2003-04-01 00:00:00
abstract:BACKGROUND:Aggressive non-Hodgkin's lymphoma is now often curable with chemotherapy. The International Prognostic Index (IPI) was recently developed to predict patient survival on the basis of pretreatment clinical features. However, classical multivariate regression models such as the IPI fail to detect time-dependent...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:
更新日期:1998-05-15 00:00:00
abstract::A primary fibrosarcoma of the thyroid occurring in a patient with a nodular goiter is described. Light microscopy showed interwoven bundles of spindle cells admixed with plump ovoid cells, and foci of multinucleated giant cells. Remnants of distorted thyroid follicles were found only at the periphery of the tumor. "Tr...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197908)44:2<584::aid-cncr2820440
更新日期:1979-08-01 00:00:00
abstract::The anniversary of the first publication of Cancer provides an opportunity to review the progress in liver cancer surgery in the past 60 years. Indeed, the past half century has been witness to remarkable advances in liver surgery that have provided benefit to so many patients afflicted with primary or secondary liver...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.23652
更新日期:2008-10-01 00:00:00
abstract::First implemented in 1990, patient navigation interventions are emerging today as an approach to reduce cancer disparities. However, there is lack of consensus about how patient navigation is defined, what patient navigators do, and what their qualifications should be. Little is known about the efficacy and cost-effec...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.23815
更新日期:2008-10-15 00:00:00
abstract::In order to quantify the lymphocyte to epithelial cell ratio (L/E ratio of the thymoma, actual counting was performed. The L/E ratio was investigated in 25 specimens of 22 cases (22 initial tumors and 3 recurrent tumors). L/E ratios ranged from 0.27 to 4.10, and the mean value was 1.93 +/- 0.21. The mean L/E ratio of ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197709)40:3<1222::aid-cncr282040
更新日期:1977-09-01 00:00:00
abstract:BACKGROUND:This study sought to evaluate patient-reported health-related quality of life following proton therapy for prostate cancer in men ≤ 60 years old. METHODS:Between August 2006 and January 2010, 262 hormone-naive men ≤ 60 years old were treated with definitive proton therapy for prostate cancer. Before treatme...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.27398
更新日期:2012-09-15 00:00:00
abstract::The presentation, growth patterns, and response to therapy of 11 consecutive children with choroid plexus carcinomas were analyzed, and the results were compared with the outcome reported in other series. Patients were a median of 26 months of age at diagnosis. Two patients had thalamic tumors, one had a posterior fos...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19920115)69:2<580::aid-cncr28206
更新日期:1992-01-15 00:00:00
abstract:BACKGROUND:While acute pancreatitis is a recognized complication of numerous drugs, cytarabine's role in causing this complication is controversial. Approximately 15 cases have been reported to the Food and Drug Administration linking cytarabine with pancreas-related toxicities. Previous case reports have been complica...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0142(19960615)77:12<2588::AID-C
更新日期:1996-06-15 00:00:00
abstract::One hundred thirty patients with histologically verified primary fibrosarcoma of bone, unassociated with any pre-existent benign bone condition, were treated at Memorial Sloan-Kettering Cancer Center between 1918 and 1973. This series of cases represents approximately 5% of primary malignant bone tumors treated in our...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197503)35:3<837::aid-cncr2820350
更新日期:1975-03-01 00:00:00
abstract:BACKGROUND:Accurate assessment of HER-2 status is necessary prior to anti-HER-2 antibody (trastuzumab) therapy for metastatic breast carcinoma. However, controversy exists regarding whether to assess HER-2 status in the primary tumor or in metastatic lesions. It is also unclear whether HER-2 status can change during di...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.20987
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:The causal relation between high-risk human papillomavirus (HPV) and cervical cancer and its precursor lesions has led to the use of sensitive HPV molecular tests for screening. This study examined the impact of the baseline HPV status on the future risk of cervical intraepithelial neoplasia grade 2 or worse...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31788
更新日期:2019-01-15 00:00:00
abstract:BACKGROUND:Since mid-1987, 29 patients with invasive transitional cell carcinoma of the urinary bladder (T1-3 N0-X M0) were treated with concurrent radiation therapy (RT) (target dose [TD], 62-66 Gy) 1.8-2.0 Gy/day for 5 days a week with a break in the middle of treatment of 2-3 weeks and vinblastine weekly 2 mg/5-12 h...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(19921215)70:12<2885::aid-cncr282
更新日期:1992-12-15 00:00:00
abstract::Surgical removal of bulky metastases of non-seminomatous germ-cell testicular cancer has been advocated as an adjuvant to chemotherapy in patients whose disease probably is too extensive to be cured by chemotherapy or surgery alone. However, in 8 of our patients, cytoreductive surgery was followed by a sudden and dram...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800315)45:6<1498::aid-cncr2820
更新日期:1980-03-15 00:00:00
abstract:BACKGROUND:Despite the widespread use of oxaliplatin-based regimens for colorectal and other gastrointestinal cancers, there is surprisingly little information regarding their empiric use for the treatment of carcinoma of unknown primary site (CUP). In the current study, the combination of oxaliplatin and capecitabine ...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.25029
更新日期:2010-05-15 00:00:00
abstract::Between 1964 and 1982, 862 patients with acute leukemia who were collected from medical institutions throughout the country had a survival of 5 years or longer. Their remission has been achieved mainly with a combination therapy of vincristine and prednisone in childhood acute leukemia and daunomycin, cytosine arabino...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850701)56:1<88::aid-cncr282056
更新日期:1985-07-01 00:00:00
abstract:BACKGROUND:Thyroid carcinomas historically have been divided into two groups according to their presumedly separate embryonic origins: those of neuroectodermal derivation (parafollicular or medullary carcinoma [MCT]) and those of foregut endodermal origin (follicular and papillary carcinomas). The validity of this conc...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19940801)74:3<928::aid-cncr28207
更新日期:1994-08-01 00:00:00
abstract::A case report of a metastasizing basal cell carcinoma is presented, primary in the leg with regional inguinal lymph node metastasis, followed by extensive metastasis to skin and bone marrow with myelophthisic anemia and terminal splenohepatic and unilateral adrenal metastasis. ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(196810)22:4<879::aid-cncr2820220
更新日期:1968-10-01 00:00:00
abstract::A 55-year-old man is reported who initially developed chronic lymphocytic leukemia. Seven years later, after chemotherapy with chlorambucil, chronic myelogenous leukemia was diagnosed in addition to the chronic lymphocytic leukemia. Four previously reported cases with the same sequence of events are reviewed as well a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(1984)54:4<697::aid-cncr282054041
更新日期:1984-08-15 00:00:00
abstract::Kaposi's sarcoma developed in two lymphoma patients previously treated by chemotherapy and chemoirradiation. The histologic picture in the two cases showed a non-Hodgkin's lymphoma with multifocal epithelioid histiocytic reaction. Both patients had Hepatitis-B surface antigen and other infections due to herpes and str...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(1984)54:4<773::aid-cncr282054043
更新日期:1984-08-15 00:00:00
abstract:BACKGROUND:The effects of relaxin (RLX) on the human breast adenocarcinoma cell line MCF-7 have been evaluated. METHODS:The cells were maintained in culture with Dulbecco's modified Eagle's medium with 1% and 10% fetal calf serum. Highly purified porcine RLX was added at concentrations ranging between 10(-11) and 10(-...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19920801)70:3<639::aid-cncr28207
更新日期:1992-08-01 00:00:00
abstract::Data from a hospital-based case-control study between 1985-1990 were used to examine the effects of tobacco, alcohol, asbestos, and other occupational exposures on laryngeal cancer risk in 194 white men with primary cancer of the larynx and 184 age-matched control subjects. A dose-dependent effect for current cigarett...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19920501)69:9<2244::aid-cncr2820
更新日期:1992-05-01 00:00:00
abstract:BACKGROUND:Chordoma and chondrosarcoma of the skull base are frequently amalgamated because of similar anatomic location, clinical presentation, and radiologic findings. The chondroid chordoma variant has been reported to carry a better prognosis. The objective of the current study was to investigate the distinctions b...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23073
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Cyclins, cyclin dependent kinases (cdks), and their inhibitors act in combination to regulate progression through the cell cycle and often are dysregulated in carcinoma. The authors hypothesized that cyclin E plays an important role in ovarian carcinogenesis and that its overexpression may be an indicator of...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21767
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Treatment with traditional cytotoxic chemotherapy regimens containing streptozocin or dacarbazine has resulted in only marginal benefit for patients with metastatic neuroendocrine tumors. The use of these regimens has been further limited by their potential toxicity. Gemcitabine is generally well tolerated a...
journal_title:Cancer
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/cncr.20466
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:The association of community factors and outcomes after hematopoietic cell transplantation (HCT) has not been comprehensively described. Using the County Health Rankings and Roadmaps (CHRR) and the Center for International Blood and Marrow Transplant Research (CIBMTR), this study evaluated the impact of comm...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.33232
更新日期:2021-02-15 00:00:00