EEG phenotypes predict treatment outcome to stimulants in children with ADHD.


:This study demonstrates that the EEG phenotypes as described by Johnstone, Gunkelman & Lunt are identifiable EEG patterns with good inter-rater reliability. Furthermore, it was also demonstrated that these EEG phenotypes occurred in both ADHD subjects as well as healthy control subjects. The Frontal Slow and Slowed Alpha Peak Frequency and the Low Voltage EEG phenotype discriminated ADHD subjects best from controls (however the difference was not significant). The Frontal Slow group responded to a stimulant with a clinically relevant decreased number of false negative errors on the CPT. The Frontal Slow and Slowed Alpha Peak Frequency phenotypes have different etiologies as evidenced by the treatment response to stimulants. In previous research Slowed Alpha Peak Frequency has most likely erroneously shown up as a frontal theta sub-group. This implies that future research employing EEG measures in ADHD should avoid using traditional frequency bands, but dissociate Slowed Alpha Peak Frequency from frontal theta by taking the individual alpha peak frequency into account. Furthermore, the divergence from normal of the frequency bands pertaining to the various phenotypes is greater in the clinical group than in the controls. Investigating EEG phenotypes provides a promising new way to approach EEG data, explaining much of the variance in EEGs and thereby potentially leading to more specific prospective treatment outcomes.


J Integr Neurosci


Arns M,Gunkelman J,Breteler M,Spronk D




Has Abstract


2008-09-01 00:00:00












  • Clinical Neuropathology practice guide 4-2013: post-herpes simplex encephalitis: N-methyl-Daspartate receptor antibodies are part of the problem.

    abstract::Classic herpes simplex virus encephalitis (HSVE) is an acute viral infection that usually follows a monophasic disease course; however some patients, mainly children, experience a relapse within weeks or months after the initial event. In a subset of these patients a viral reactivation is unlikely because the CSF PCR ...

    journal_title:Clinical neuropathology

    pub_type: 杂志文章


    authors: Höftberger R,Armangue T,Leypoldt F,Graus F,Dalmau J

    更新日期:2013-07-01 00:00:00

  • Expression of p53 oncoprotein and bcl-2 in renal cell carcinoma.

    abstract:OBJECTIVE:The aim of the present study was to investigate the significance of p53 and bcl-2 as prognostic factors among others in renal cell carcinoma patients. METHODS:We evaluated the stages, histological grades, tumor diameters, cellular patterns and the presence of mutant p53 protein and bcl-2 overexpression in 57...

    journal_title:Saudi medical journal

    pub_type: 杂志文章


    authors: Uzunlar AK,Sahin H,Yilmaz F,Ozekinci S

    更新日期:2005-01-01 00:00:00

  • Innovation in prediction planning for anterior open bite correction.

    abstract::This study applies recent advances in 3D virtual imaging for application in the prediction planning of dentofacial deformities. Stereo-photogrammetry has been used to create virtual and physical models, which are creatively combined in planning the surgical correction of anterior open bite. The application of these no...

    journal_title:Australian orthodontic journal

    pub_type: 杂志文章


    authors: Almuzian M,Almukhtar A,O'Neil M,Benington P,Al Anezi T,Ayoub A

    更新日期:2015-05-01 00:00:00

  • Hemangiopericytoma of the meninges: a clinicopathologic and immunohistochemical study.

    abstract::This clinicopathologic study concerns 15 cases of hemangiopericytoma of the meninges (so-called hemangiopericytic meningioma) among approximately 300 examined cases. Ages of the patients at the first surgery ranged from 25 to 67 years, with a median of 44 years. According to follow-up information, 9 of the 15 died bet...

    journal_title:Clinical neuropathology

    pub_type: 杂志文章


    authors: Iwaki T,Fukui M,Takeshita I,Tsuneyoshi M,Tateishi J

    更新日期:1988-05-01 00:00:00

  • Inhibitory effects of crude drugs on alpha-glucosidase.

    abstract::The inhibitory activity of several crude drugs on alpha-glucosidases, which are the key enzymes for carbohydrate digestion and the prevention of diabetic complications, was investigated. Several crude drugs including Terminaliae Fructus, Mori Cortex Radicis, Caesalpiniae Lignum and Gyrophora esculenta potently inhibit...

    journal_title:Archives of pharmacal research

    pub_type: 杂志文章


    authors: Choi HJ,Kim NJ,Kim DH

    更新日期:2000-06-01 00:00:00

  • A giant abdominal cyst with raised levels of carbohydrate antigen 19-9.

    abstract::A 53-year-old woman was admitted with upper abdominal discomfort. Clinical examination revealed a mass of the upper left quadrant. Computed tomography disclosed a giant cystic lesion of 19 x 16 cm compressing the body and tail of the pancreas as well as the left kidney. Endoscopic ultrasound showed an anechoic lesion ...

    journal_title:Acta gastro-enterologica Belgica

    pub_type: 杂志文章


    authors: Kisoka P,Mavrogenis G,Warzee P,Hoebeke Y

    更新日期:2013-12-01 00:00:00

  • Comparison of different maintenance strategies within supportive implant therapy for prevention of peri-implant inflammation during the first year after implant restoration. A randomized, dental hygiene practice-based multicenter study.

    abstract:PURPOSE:This randomized clinical multicenter study compared different professional preventive approaches on peri-implant inflammation under supportive implant therapy (SIT). METHODS:105 participants (167 implants) were randomly allocated to four groups. All participants were under SIT with a 3-month recall interval. P...

    journal_title:American journal of dentistry

    pub_type: 临床试验,随机对照试验


    authors: Ziebolz D,Klipp S,Schmalz G,Schmickler J,Rinke S,Kottmann T,Fresmann S,Einwag J

    更新日期:2017-08-01 00:00:00

  • [Eosinophilic enteritis as a rare cause of ascites].

    abstract::Eosinophilic gastroenteritis is an infrequent entity characterized by tissular eosinophilia that can affect different layers of the intestinal wall. This entity can affect any area of the digestive apparatus from the esophagus to the rectum. Clinical manifestations depend on the affected layers and range from barely p...

    journal_title:Gastroenterologia y hepatologia

    pub_type: 杂志文章


    authors: Bouhmidi A,Lorente Poyatos R,Romero Cara P,Ibáñez Martín JJ,Casado Caballero F,Quintero Fuientes D,Martín Ruiz JL

    更新日期:2003-10-01 00:00:00

  • Hydroxyurea toxicity combined with didanosine (ddl) in HIV-1-seropositive asymptomatic individuals.

    abstract:OBJECTIVE:Hydroxyurea, a carbamate compound widely used for the treatment of myeloproliferative disorders, has been investigated in several clinical trials conducted in the setting of HIV infection, where it is given in combination regimens almost always containing didanosine (ddI). Hydroxyurea mainly acts as a ribonuc...

    journal_title:International journal of clinical pharmacology and therapeutics

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Seminari E,Lisziewicz J,Tinelli C,Foli A,Lori F,Maserati R

    更新日期:1999-10-01 00:00:00

  • Male-biased investment in fallow deer: an experimental study.

    abstract::To find the causes of faster growth in males, we studied the growth and behaviour of six male and five female fallow deer, Dama dama, fawns, hand-reared on the same amount and quality of milk, and compared them with naturally reared fawns. The bottle-reared fawns grew more slowly. In particular, the difference in weig...

    journal_title:Animal behaviour

    pub_type: 杂志文章


    authors: Birgersson B,Tillbom M,Ekvall K

    更新日期:1998-08-01 00:00:00

  • Primary retroperitoneal mucinous cystadenoma.

    abstract::Primary mucinous neoplasms of the retroperitoneum, including mucinous cystadenocarcinomas, mucinous borderline tumors, and mucinous cystadenomas are uncommon tumors found exclusively in women. Since the retroperitoneum does not contain mucinous epithelium, the origin, and histogenesis of these tumors remain unclear. I...

    journal_title:Saudi medical journal

    pub_type: 杂志文章


    authors: Abedalthagafi M,Jackson PG,Ozdemirli M

    更新日期:2009-01-01 00:00:00

  • A Rare Non-Hemolytic Case of Idiopathic Cold Agglutinin Disease.

    abstract:BACKGROUND:Cold agglutinin disease is a very rare condition associated with agglutination of erythrocytes in cold environment usually due to IgM type antibodies. Other than hemolytic anemias, it may interfere with routine hemogram tests due to miscalculation of red blood cell count (RBC) and other hemogram parameters c...

    journal_title:Clinical laboratory



    authors: Erkus E,Kocak MZ,Aktas G,Ozen M,Atak BM,Duman TT,Tekce BK,Savli H

    更新日期:2018-06-01 00:00:00

  • Inhibition of pancreatic secretion to prevent postoperative complications following pancreatic resection.

    abstract::Major pancreatic resection still nowadays carries a considerable risk for morbidity and even mortality. Complications occurring after pancreatic surgery are chiefly linked with exocrine pancreatic secretion. Therefore to inhibit exocrine pancreatic secretion perioperatively, seems to be a promising concept in the prev...

    journal_title:Acta gastro-enterologica Belgica

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Büchler M,Friess H

    更新日期:1993-05-01 00:00:00

  • [Correlation between the presence of type-2 anti-pemphigoid antibodies and dementia in elderly subjects with no clinical signs of pemphigoid].

    abstract:BACKGROUND:Pemphigoid is a form of auto-immune bullous dermatosis characterised by the production of antibodies directed against components of hemidesmosomes in the basal membrane. The physiopathological process responsible for unmasking of these antigens is unknown. Pemphigoid is more common in elderly subjects and is...

    journal_title:Annales de dermatologie et de venereologie

    pub_type: 杂志文章


    authors: Foureur N,Mignot S,Senet P,Verpillat P,Picard-Dahan C,Crickx B,Labarre C,Nicaise-Roland P,Descamps V

    更新日期:2006-05-01 00:00:00

  • [Mills' syndrome: a rare clinical entity].

    abstract:INTRODUCTION:Mills' syndrome is a rare motor neuron disease, initially described by Mills in 1900 as a progressive ascending or descending hemiplegia without significant sensory involvement. This syndrome is of uncertain nosological status, and is supposedly due to unilateral primary degeneration of corticospinal pathw...

    journal_title:Revue neurologique

    pub_type: 杂志文章


    authors: Lachaud S,Soriani MH,Delmont E,Budai M,Desnuelle C,Lebrun C

    更新日期:2007-03-01 00:00:00

  • Multimodality imaging of splenic sclerosing angiomatoid nodular transformation.

    abstract::Sclerosing angiomatoid nodular transformation (SANT) is an exceedingly rare, benign and proliferative vascular lesion that arises from the splenic red pulp. It is often an incidental finding on imaging. The diagnosis of SANT is confirmed via histopathological examination of the resected spleen. Herein, we present a ca...

    journal_title:Singapore medical journal

    pub_type: 杂志文章


    authors: Lim HT,Tan CH,Teo LT,Ho CS

    更新日期:2015-06-01 00:00:00

  • Anterior hypospadias. Is repair necessary with urination in a sitting or squatting position?

    abstract:OBJECTIVE:To determine the chronic complication rate of anterior hypospadias repair and to explore whether the practice of placing the neomeatus at the tip of the penis should be applicable to all cases in our community where urination is in a sitting/squatting position. METHODS:Over a 10-year period commencing 1st Se...

    journal_title:Saudi medical journal

    pub_type: 杂志文章


    authors: Anikwe RM,Kamal BA,Hegazi MM,Hashish M,El-Darawani H,Taha SA

    更新日期:2000-04-01 00:00:00

  • What makes the prefrontal cortex so appealing in the era of brain imaging? a network analytical perspective.

    abstract::It is thought that the prefrontal cortex (PFC) subserves cognitive control processes by coordinating the flow of information in the cerebral cortex. In the network of cortical areas the central position of the PFC makes difficult to dissociate processing and the cognitive function mapped to this region, especially whe...

    journal_title:Acta biologica Hungarica

    pub_type: 杂志文章


    authors: Négyessy L,Bányai M,Nepusz T,Bazsó F

    更新日期:2012-01-01 00:00:00

  • Paraneoplastic syndromes: Definitions, classification, pathophysiology and principles of treatment.

    abstract::Paraneoplastic syndromes (PNS) are rare clinical syndromes due to the systemic effects of tumours; they are unrelated to tumour size, invasiveness or metastases. Recent years have seen considerable advances leading to improved understanding of their pathophysiology and increased recognition of new PNS entities and PNS...

    journal_title:Seminars in diagnostic pathology

    pub_type: 杂志文章,评审


    authors: Henry K

    更新日期:2019-07-01 00:00:00

  • Increased Intact Proinsulin in the Oral Glucose Challenge Sample is an Early Indicator for Future Type 2 Diabetes Development - Case Reports and Evidence from the Literature.

    abstract:BACKGROUND:Increased intact proinsulin in plasma is a highly specific biomarker for a major disruption of insulin-processing in the pancreatic β-cells with associated insulin resistance. Increased intact proinsulin in morning fasting plasma indicates not only incipient diabetes, but also increased risk of macrovascular...

    journal_title:Clinical laboratory



    authors: Pfützner A,Manessis A,Hanna MR,Lewin J

    更新日期:2020-05-01 00:00:00

  • Zooxanthellar symbiosis in planula larvae of the coral Pocillopora damicornis.

    abstract::We characterized the planular-zooxanthellae symbiosis of the coral Pocillopora damicornis using criteria that are familiar in studies on corals. Similar to adult corals, planulae exhibited photoacclimation, as changes in symbiont chlorophyll a (chl a); changes in the light-saturation constant for photosynthesis (I(k))...

    journal_title:Journal of experimental marine biology and ecology

    pub_type: 杂志文章


    authors: Gaither MR,Rowan R

    更新日期:2010-04-30 00:00:00

  • The patient protection and affordable care act: what does it mean for mental health services for older adults?

    abstract::The U.S. Supreme Court recently upheld the constitutionality of the Patient Protection and Affordable Care Act (PPACA). It is important to think about how this act will affect mental health services for older adults. The act has the potential to improve health outcomes across all income and age groups. There are speci...

    journal_title:Journal of psychosocial nursing and mental health services

    pub_type: 杂志文章


    authors: Sorrell JM

    更新日期:2012-11-01 00:00:00

  • Camille Flammarion on the powers of the soul; with an introduction by Carlos S.

    abstract::There is a long conceptual tradition that interprets phenomena such as clairvoyance and apparitions as evidence for a spiritual component in human beings. Examples of this appear in the literatures of mesmerism, Spiritualism and psychical research. The purpose of this Classic Text is to present excerpts from a book by...

    journal_title:History of psychiatry

    pub_type: 杂志文章


    authors: Alvarado CS,Zingrone NL

    更新日期:2020-06-01 00:00:00

  • Predicting symptom clusters of posttraumatic stress disorder (PTSD) in Croatian war veterans: the role of socio-demographics, war experiences and subjective quality of life.

    abstract:BACKGROUND:Previous research has documented multiple chains of risk in the development of PTSD among war veterans. However, existing studies were mostly carried out in the West, while they also did not analyze specific symptom clusters of PTSD. The aim of this study was to examine the role of socio-demographic characte...

    journal_title:Psychiatria Danubina

    pub_type: 杂志文章


    authors: Lončar M,Plašć ID,Bunjevac T,Hrabač P,Jakšić N,Kozina S,Henigsberg N,Sagud M,Marčinko D

    更新日期:2014-09-01 00:00:00

  • Epidemiology of pediatric hand fractures presenting to a university hospital in Central Saudi Arabia.

    abstract:OBJECTIVES:To investigate the epidemiology of pediatric hand fractures and to provide recommendations regarding prevention. METHODS:Medical records and x-rays were retrospectively reviewed for age at the time of injury, gender, fracture pattern, place where the injury occurred, and mechanism of injury. The study was c...

    journal_title:Saudi medical journal

    pub_type: 杂志文章


    authors: Al-Jasser FS,Mandil AM,Al-Nafissi AM,Al-Ghamdi HA,Al-Qattan MM

    更新日期:2015-05-01 00:00:00

  • Free, brief, and validated: Standardized instruments for low-resource mental health settings.

    abstract::Evidence-based assessment has received little attention despite its critical importance to the evidence-based practice movement. Given the limited resources in the public sector, it is necessary for evidence-based assessment to utilize tools with established reliability and validity metrics that are free, easily acces...

    journal_title:Cognitive and behavioral practice

    pub_type: 杂志文章


    authors: Beidas RS,Stewart RE,Walsh L,Lucas S,Downey MM,Jackson K,Fernandez T,Mandell DS

    更新日期:2015-02-01 00:00:00

  • Daily low-dose cisplatin and concurrent thoracic irradiation for poor-risk patients with unresectable non-small-cell lung cancer.

    abstract::A pilot study was conducted to assess the efficacy and feasibility of daily low-dose cisplatin with concurrent thoracic irradiation for clinically unresectable non-small-cell lung cancer (NSCLC). Patients with inoperable NSCLC who had poor risk factors such as advanced age, poor performance status, poor lung function,...

    journal_title:Acta medica Okayama

    pub_type: 临床试验,杂志文章


    authors: Takata I,Ueoka H,Kiura K,Tabata M,Takigawa N,Katayama H,Takemoto M,Hiraki Y,Harada M,Tanimoto M

    更新日期:2002-10-01 00:00:00

  • Experience and lessons from the use of lepromin and Mycobacterium leprae-specific serology.

    abstract::Skin testing with lepromin, which produces a delayed-type hypersensitivity reaction, has been used in the classification of leprosy, and a good correlation has been found between immunological status and the reaction to lepromin. In addition, the prognostic value of the lepromin test has been demonstrated. More recent...

    journal_title:Leprosy review

    pub_type: 杂志文章,评审


    authors: Sengupta U

    更新日期:2000-12-01 00:00:00

  • A survey of the training needs of the National Panel of Specialists.

    abstract:BACKGROUND:A survey of National Panellists (NPs) in Scotland was undertaken to establish their current skill base and what training would be required to enable them to carry out appointment committee responsibilities effectively. METHODS:A questionnaire was sent to all NPs in November 2005 requesting their views on th...

    journal_title:Scottish medical journal

    pub_type: 杂志文章


    authors: Tochel C,Williams B

    更新日期:2007-08-01 00:00:00

  • [Hospital mortality at the Manuel Velasco Suárez National Institute of Neurology and Neurosurgery (1995-2001)].

    abstract:UNLABELLED:To improve health policies directed toward ameliorating quality and also to characterize the profile of patients who attend medical centers, it is necessary to determine causes of mortality in any healthcare organization. OBJECTIVE:To analyze time-trend hospital mortality at the Manuel Velasco Suárez Nation...

    journal_title:Gaceta medica de Mexico

    pub_type: 杂志文章


    authors: Velásquez-Pérez L,Jiménez-Marcial ME

    更新日期:2004-05-01 00:00:00