Relationships among stellate cell activation, progenitor cells, and hepatic regeneration.

Abstract:

:Hepatic stellate cells (HSC) play an important role in liver fibrogenesis. They are also key players in liver regeneration as part of the stem cell niche of hepatocytes and hepatic progenitor cells. They produce growth stimulating and inhibiting factors for these epithelial cell compartments. In addition, recent studies suggest a role for HSCs themselves for being progenitors of epithelial cells through a transitional mesenchymal phase.

journal_name

Clin Liver Dis

journal_title

Clinics in liver disease

authors

Roskams T

doi

10.1016/j.cld.2008.07.014

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

853-60, ix

issue

4

eissn

1089-3261

issn

1557-8224

pii

S1089-3261(08)00083-4

journal_volume

12

pub_type

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