The effect of a single dose versus a daily dose of cholecalciferol on the serum 25-hydroxycholecalciferol and parathyroid hormone levels in the elderly with secondary hyperparathyroidism living in a low-income housing unit.

abstract：:The aim of this observational, non-randomized study was to clarify the unknown effects of switching oral bisphosphonates (BPs) to denosumab (DMAb) or daily teriparatide (TPTD) in patients with rheumatoid arthritis (RA). The characteristics of the 194 female patients included in the study were 183 postmenopausal, age 6...

journal_title：Journal of bone and mineral metabolism

authors： Ebina K,Hirao M,Hashimoto J,Hagihara K,Kashii M,Kitaguchi K,Matsuoka H,Iwahashi T,Chijimatsu R,Yoshikawa H

更新日期：2018-07-01 00:00:00

abstract：:Interleukin-11 (IL-11) is a bone marrow stromal fibroblast-derived cytokine with a wide spectrum of activities in different biological systems. IL-11 and IL-6 are two cytokines known to rely on osteoblast-osteoclast communication for their effects on osteoclast differentiation. Bone sialoprotein (BSP) is a mineralized...

journal_title：Journal of bone and mineral metabolism

authors： Matsumura H,Nakayama Y,Takai H,Ogata Y

更新日期：2015-03-01 00:00:00

abstract：:Apolipoprotein E (Apo E) polymorphism has been implicated in many chronic diseases, including Alzheimer disease and osteoporosis. Significant association of the Apo E4 allele to low bone mineral density (BMD) has been repeatedly reported. We here examined the Apo E genotype frequencies in the Chinese population (n = 6...

journal_title：Journal of bone and mineral metabolism

authors： Wong SY,Lau EM,Li M,Chung T,Sham A,Woo J

更新日期：2005-01-01 00:00:00

abstract：:Notch is a transmembrane protein involved in cell fate determination. In the present study, we observed temporally and spatially restricted expression of Notch1 in developing cartilage. Notch1 was localized starting from the mesenchymal condensation stage of embryonic mouse forelimbs. Interestingly, although localizat...

journal_title：Journal of bone and mineral metabolism

authors： Watanabe N,Tezuka Y,Matsuno K,Miyatani S,Morimura N,Yasuda M,Fujimaki R,Kuroda K,Hiraki Y,Hozumi N,Tezuka K

更新日期：2003-01-01 00:00:00

abstract：:Sarcopenia is an age-related loss of skeletal muscle mass and strength. It has been widely recognized that low muscle mass was essential in the diagnosis of sarcopenia, whereas recent studies have emphasized the importance of muscle strength. In practice, muscle quality as well as muscle mass might determine the stren...

journal_title：Journal of bone and mineral metabolism

authors： Yakabe M,Hosoi T,Akishita M,Ogawa S

更新日期：2020-01-01 00:00:00

abstract：:Data from retrospective and prospective observational and case-control studies suggest that activity is associated with reduced fracture risk, but consistently replicated bias may be responsible for this desired endpoint. Exercise during growth is likely to build a larger and stronger skeleton. However, cessation of e...

journal_title：Journal of bone and mineral metabolism

authors： Seeman E

更新日期：2005-01-01 00:00:00

abstract：:In the course of complex regional pain syndrome (CRPS), local osteopenia in the subchondral/subcortical areas of the affected limb represents a central manifestation. Mechanistic aspects of CRPS-associated pathologies remain unclear, and knowledge about bone morphology in CRPS-affected areas is rare. The aim of this s...

journal_title：Journal of bone and mineral metabolism

authors： Oehler N,Rolvien T,Schmidt T,Butscheidt S,Oheim R,Barvencik F,Mussawy H

更新日期：2019-07-01 00:00:00

abstract：:Fracture healing is a complex biological process involving the proliferation of mesenchymal progenitor cells, and chondrogenic, osteogenic, and angiogenic differentiation. The mechanisms underlying the proliferation and differentiation of mesenchymal progenitor cells remain unclear. Here, we demonstrate Dickkopf-relat...

journal_title：Journal of bone and mineral metabolism

authors： Mori Y,Adams D,Hagiwara Y,Yoshida R,Kamimura M,Itoi E,Rowe DW

更新日期：2016-11-01 00:00:00

abstract：:Histomorphometry is commonly applied to study bone remodeling. Histological definitions of cortical bone boundaries have not been consistent. In this study, new criteria for specific definition of the transitional zone between the cortical and cancellous bone in the femoral neck were developed. The intra- and inter-ob...

journal_title：Journal of bone and mineral metabolism

authors： Tong XY,Malo M,Tamminen IS,Isaksson H,Jurvelin JS,Kröger H

更新日期：2015-01-01 00:00:00

abstract：:Senile or age-related/dependent osteoporosis is caused by reduced bone formation, rather than increased bone resorption as in postmenopausal osteoporosis. Here we review genetically engineered mouse models with defects in osteoblastic proliferation or differentiation with focus on IGF signaling and stem cells. Model m...

journal_title：Journal of bone and mineral metabolism

authors： Hishiya A,Watanabe K

更新日期：2004-01-01 00:00:00

abstract：:Stimulation of osteoblast proliferation and differentiation is important for the in vivo bone-bonding ability of biomaterials. Previous in vitro studies have used biochemical assays to analyze osteoblast-specific gene expression in cultured osteoblasts. In this study, we generated transgenic mice harboring a monomeric...

journal_title：Journal of bone and mineral metabolism

authors： Tsukanaka M,Yamamoto K,Fujibayashi S,Pattanayak DK,Matsushita T,Kokubo T,Matsuda S,Akiyama H

更新日期：2014-11-01 00:00:00

abstract：:Based on the relationship between bone strength, trabecular skeletal structure, and bone mineral density (BMD), structure parameters for assessing vertebral bone strength were studied using 18 cancellous bone blocks from the third lumbar vertebra of elderly persons. The trabecular bone pattern of each bone block was b...

journal_title：Journal of bone and mineral metabolism

authors： Tanaka T,Sakurai T,Kashima I

更新日期：2001-01-01 00:00:00

abstract：:Bone development up to early adulthood plays an important role in determining the risk of osteoporosis later in life. However, bone development in children has not been fully documented by longitudinal studies in Japanese children. The purpose of this study is to determine the degree of tracking of areal bone mineral ...

journal_title：Journal of bone and mineral metabolism

authors： Fujita Y,Iki M,Ikeda Y,Morita A,Matsukura T,Nishino H,Yamagami T,Kagamimori S,Kagawa Y,Yoneshima H

更新日期：2011-03-01 00:00:00

abstract：:The effects of basic fibroblast growth factor (bFGF) on osteogenic differentiation in-vivo were investigated using a rat bone marrow ablation model. bFGF was infused directly into rat femora for 6 days after bone marrow ablation. The contralateral femur was infused with vehicle only and used as control. Bone formation...

journal_title：Journal of bone and mineral metabolism

authors： Tanaka H,Wakisaka A,Ogasa H,Kawai S,Liang CT

更新日期：2003-01-01 00:00:00

abstract：:Bone is a specialized connective tissue that functions as the load-bearing structure of the body. Free radicals may affect bone remodeling by regulating osteoclast activity in either the physiological or pathological condition. Vitamin E, a lipid-soluble antioxidant, has been demonstrated to offer protection against o...

journal_title：Journal of bone and mineral metabolism

authors： Mehat MZ,Shuid AN,Mohamed N,Muhammad N,Soelaiman IN

更新日期：2010-09-01 00:00:00

abstract：:In 50 premenarcheal girls selected from the lowest and highest end of the calcium-intake distribution of a large population sample, we evaluated bone mineral density (BMD), together with the following hormonal-metabolic parameters: androstenedione (ASD), dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (D...

journal_title：Journal of bone and mineral metabolism

authors： Bonofiglio D,Garofalo C,Catalano S,Marsico S,Aquila S,Andò S

更新日期：2004-01-01 00:00:00

abstract：:The aim of this study was to survey the incidence of osteoporotic fragility fractures, which include vertebral, hip, distal radius, and proximal humerus fractures, in patients ≥ 50 years of age, from 2004 to 2015, in Sado City, Japan. We examined temporal changes in the incidence of these fractures from 2010 through 2...

journal_title：Journal of bone and mineral metabolism

authors： Imai N,Endo N,Shobugawa Y,Oinuma T,Takahashi Y,Suzuki K,Ishikawa Y,Makino T,Suzuki H,Miyasaka D,Sakuma M

更新日期：2019-05-01 00:00:00

abstract：INTRODUCTION:Cold intolerance is defined as abnormal pain resulting from exposure to cold stimulation after trauma. However, the pathophysiology remains unclear. We recently demonstrated that regional osteoporotic changes accompanied by high bone turnover were involved in causing pain-like behaviors in the unloaded hin...

journal_title：Journal of bone and mineral metabolism

authors： Ibe K,Iba K,Hanaka M,Kiyomoto K,Hayakawa H,Teramoto A,Emori M,Yamashita T

更新日期：2020-07-01 00:00:00

abstract：:Measurements of bone biochemical markers are increasingly being used to evaluate the state of bone turnover in the management of bone metabolic diseases, especially osteoporosis. However, changes in the bone turnover rate vary with age. The aim of this study was to establish the laboratory reference range of serum bon...

journal_title：Journal of bone and mineral metabolism

authors： Pi YZ,Wu XP,Liu SP,Luo XH,Cao XZ,Xie H,Liao EY

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Physical activity (PA) is a key factor of bone mass acquisition in peripubertal children. Sedentary behavior (SB) has been shown to influence bone outcomes. This study aimed to examine the association between objectively measured PA and SB and bone stiffness in Japanese children. MATERIALS AND METHODS:Par...

journal_title：Journal of bone and mineral metabolism

authors： Yamakita M,Ando D,Akiyama Y,Sato M,Suzuki K,Yamagata Z

更新日期：2019-11-01 00:00:00

abstract：:We aimed to clarify changes in biochemical markers of bone turnover (BTMs) over 10 years, associations with changes in bone mineral density (BMD), and birth-cohort effects in a Japanese community. We randomly selected 400 individuals (age, 40-79 years; 50 of each gender and age stratum) from a list of registered resid...

journal_title：Journal of bone and mineral metabolism

authors： Yoshimura N,Muraki S,Oka H,Kawaguchi H,Nakamura K,Akune T

更新日期：2011-11-01 00:00:00

abstract：:Osteonecrosis of the jaw (ONJ) associated with bisphosphonate therapy is a rare but severe side effect in osteoporosis patients. Recently, the number of osteoporosis patients with ONJ has dramatically increased in Japan. This has contributed to an increase in the number of patients avoiding extractions. However, there...

journal_title：Journal of bone and mineral metabolism

authors： Taguchi A,Uemura Y,Imai T,Tanaka S,Ohta H,Nakamura T,Orimo H,Sugimoto T,Soen S,Shiraki M,Adequate Treatment of Osteoporosis (A-TOP) research group.

更新日期：2019-09-01 00:00:00

abstract：:Bone mineral density (BMD) seems not to be decreased in young patients given long-term suppressive doses of levothyroxine (LT4), but information regarding the bone microstructure in these patients is lacking. The aim of this study was to determine whether supraphysiologic doses of LT4, initiated during childhood or ad...

journal_title：Journal of bone and mineral metabolism

authors： Mendonça Monteiro de Barros G,Madeira M,Vieira Neto L,de Paula Paranhos Neto F,Carvalho Mendonça LM,Corrêa Barbosa Lima I,Corbo R,Fleiuss Farias ML

更新日期：2016-07-01 00:00:00

abstract：:We have previously demonstrated the efficacy of therapeutic exercise for osteoarthritis (OA) of the knee. This study was performed to examine the additive effects of glucosamine or risedronate on the exercise therapy. In this study, 142 female patients with moderate OA of the knee, who had been recommended to undergo ...

journal_title：Journal of bone and mineral metabolism

authors： Kawasaki T,Kurosawa H,Ikeda H,Kim SG,Osawa A,Takazawa Y,Kubota M,Ishijima M

更新日期：2008-01-01 00:00:00

abstract：:Three-dimensional (3D) alteration of trabecular microarchitecture is a risk factor for vertebral fractures. Histomorphometry allows microarchitectural analysis of bone, but the necessity to perform a transiliac bone biopsy limits its use in large series of patients. X-Ray films are commonly used in routine practice an...

journal_title：Journal of bone and mineral metabolism

authors： Chappard D,Guggenbuhl P,Legrand E,Baslé MF,Audran M

更新日期：2005-01-01 00:00:00

abstract：:Concurrent use of bisphosphonate therapy reduces the anabolic effect of teriparatide. Consequently, in clinical practice bisphosphonates are discontinued and teriparatide therapy held for a few months to allow bone turnover to increase. We aimed to evaluate the effect of prior bisphosphonate exposure and the effect of...

journal_title：Journal of bone and mineral metabolism

authors： Keel C,Kraenzlin ME,Kraenzlin CA,Müller B,Meier C

更新日期：2010-01-01 00:00:00

abstract：:Gastrectomy-evoked osteopenia in the femoral metaphysis of rats can be prevented by the consumption of fructooligosaccharides (FOS). We examined the effect of FOS on the femoral neck. Twenty-eight 5-week-old male Sprague-Dawley rats were divided into two groups, sham-operated (SH) and gastrectomized (GX). One week aft...

journal_title：Journal of bone and mineral metabolism

authors： Hirama Y,Morohashi T,Sano T,Maki K,Ohta A,Sakai N,Yamada S,Sasa R

更新日期：2003-01-01 00:00:00

abstract：:The present study aimed to evaluate the prevalence and clinical presentation of Paget's disease of bone (PDB) in Japan. As PDB is a very rare disease in Japan, a nationwide mail survey was conducted targeting doctors in the specialty most frequently diagnosing and treating PDB patients in Japan. First, the literature ...

journal_title：Journal of bone and mineral metabolism

authors： Hashimoto J,Ohno I,Nakatsuka K,Yoshimura N,Takata S,Zamma M,Yabe H,Abe S,Terada M,Yoh K,Fukunaga M,Cooper C,Morii H,Yoshikawa H,Japanese Committee on Clinical Guidelines of Diagnosis and Treatment of Paget's Disease of Bone o

更新日期：2006-01-01 00:00:00

abstract：:Patients with MRI-proved acute painful vertebral fractures in whom conservative pain management fails are frequently referred for vertebroplasty. This study investigated the effects of treating osteoporosis on the mortality rate of patients with MRI-proved acute osteoporosis-related vertebral fractures who had undergo...

journal_title：Journal of bone and mineral metabolism

authors： Chen YC,Su FM,Cheng TT,Lin WC,Lui CC

更新日期：2016-05-01 00:00:00

abstract：:Vertebral fracture (VFx) is associated with various co-morbidities and increased mortality. In this paper, we have studied the detective value of height loss for VFx using two indices; historical height loss (HHL) which is the difference between the maximal height, and the current height (CH), and CH/knee height (KH) ...

journal_title：Journal of bone and mineral metabolism

authors： Yoh K,Kuwabara A,Tanaka K

更新日期：2014-09-01 00:00:00