当前位置： SCI文献检索 > HUMAN IMMUNOLOGY期刊下所有文献 > Diagnosis of tuberculosis infection in patients awaiting liver transplantation.

Diagnosis of tuberculosis infection in patients awaiting liver transplantation.

Abstract：

:This study examined the performance of a tuberculosis (TB)-specific enzyme-linked immunospot assay in 48 patients awaiting liver transplantation. They were tested with T-SPOT.TB, tuberculin skin test (TST), and lymphocyte transformation test (LTT) using tuberculin as a stimulus. A questionnaire was used to gain information on TB exposure. Four patients were defined as positive by T-SPOT.TB, 6 by TST, and 28 by LTT. The patients displaying positive results to T-SPOT.TB were also positive in the TST and LTT. We considered them to have latent TB because they were repeatedly (two or three times) positive to the T-SPOT.TB and reported TB exposure. Active TB was excluded by negative multislice computed tomography, negative culture, and absence of symptoms. In 1 patient, T-cell reactivity toward TB peptides was lost 1 and 2 months posttransplantation. Another patient, however, tested 8 and 13 months posttransplantation, displayed measurable cellular TB immune responses. This finding suggests that the measurement of cellular TB immune responses shortly after transplantation may fail. If possible, patients with end-stage liver disease should be screened for TB prior to transplantation. Our data are the first evidence that T-SPOT.TB may be useful to diagnose latent TB in patients awaiting liver transplantation.

journal_name

Hum Immunol

journal_title

Human immunology

authors

Lindemann M,Dioury Y,Beckebaum S,Cicinnati VR,Gerken G,Broelsch CE,Wrighton-Smith P,Grosse-Wilde H

doi

10.1016/j.humimm.2008.10.005

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

24-8

issue

1

eissn

0198-8859

issn

1879-1166

pii

S0198-8859(08)00499-0

journal_volume

70

pub_type

杂志文章

相关文献

HUMAN IMMUNOLOGY文献大全
  • Sequences of four splits of HLA-A10 group. Implications for serologic cross-reactivities and their evolution.

    abstract：:Nucleotide sequences of alleles encoding four serologically defined splits of the HLA-A10 group, A26.1, A26.3, A26.4, and A10SA, were determined. It was confirmed that the alleles coding for A26.1 and A26.3 are identical with A*2602 and A*2601, respectively. On the other hand, alleles for A26.4 and A10SA are thus far ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(94)90263-1

    authors： Ishikawa Y,Tokunaga K,Lin L,Imanishi T,Saitou S,Kimura A,Kashiwase K,Akaza T,Tadokoro K,Juji T

    更新日期：1994-03-01 00:00:00

  • MHC haplotype analysis by artificial neural networks.

    abstract：:Conventional matching is based on numbers of alleles shared between donor and recipient. This approach, however, ignores the degree of relationship between alleles and haplotypes, and therefore the actual degree of difference. To address this problem, we have compared family members using a block matching technique wh...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/s0198-8859(97)00231-0

    authors： Bellgard MI,Tay GK,Hiew HL,Witt CS,Ketheesan N,Christiansen FT,Dawkins RL

    更新日期：1998-01-01 00:00:00

  • Siglec-10 expression is up-regulated in activated human CD4+ T cells.

    abstract：:Most sialic acid-binding immunoglobulin-like lectins (Siglecs) suppress immune cell function but are expressed at low levels on human T cells. We found that soluble CD52 inhibited T cell signalling by ligating Siglec-10, but the presence of Siglec-10 on human T cells has been questioned. To address this concern, we ex...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2020.01.009

    authors： Bandala-Sanchez E,Bediaga NG,Naselli G,Neale AM,Harrison LC

    更新日期：2020-01-01 00:00:00

  • Elevation of HLA-G-expressing DC-10 cells in patients with gastric cancer.

    abstract：:DC-10 is a distinct subset of human tolerogenic dendritic cells (DCs) which express high levels of human leukocyte antigen-G (HLA-G). DC-10 could induce adaptive type 1 regulatory T cells through the IL-10 dependent ILT4/HLA-G signaling pathway. However, the significance of DC-10 in malignancies remains unclear. In th...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2016.01.003

    authors： Xu DP,Shi WW,Zhang TT,Lv HY,Li JB,Lin A,Yan WH

    更新日期：2016-09-01 00:00:00

  • Association analysis of class II cytokine and receptor genes in vitiligo patients.

    abstract：:The loss of melanocytes in vitiligo is mainly attributed to defective autoimmune mechanisms and lately autoinflammatory mediators have become more emphasized. Among these, a number of class II cytokines and their receptors have displayed altered expression patterns in vitiligo. Thus, we selected 30 SNPs from the regio...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2015.09.050

    authors： Traks T,Karelson M,Reimann E,Rätsep R,Silm H,Vasar E,Kõks S,Kingo K

    更新日期：2016-05-01 00:00:00

  • A 70 kDa MHC class I associated protein (MAP-70) identified as a receptor molecule for Coxsackievirus A9 cell attachment.

    abstract：:One of the major categories of disease-causing micro-organisms are viruses. New studies on many different viruses have shown that virus attachment and cell entry is often a multistep process, requiring many interactions between the virus and cell surface molecules. In this study, we have attempted to identify the cell...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/s0198-8859(00)00151-8

    authors： Triantafilou M,Triantafilou K,Wilson KM

    更新日期：2000-09-01 00:00:00

  • Up-regulation of DNAM-1 and NKp30, associated with improvement of NK cells activation after long-term culture of mononuclear cells from patients with ovarian neoplasia.

    abstract：:This study aimed at evaluating the functional activation and activating receptors expression on resting, short- and long-term NK and NK-like T cells from blood of ovarian neoplasia patients. Blood from patients with adnexal benign alterations (n = 10) and ovarian cancer (grade I-IV n = 14) were collected after signed ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2014.05.010

    authors： da Silva RF,Petta CA,Derchain SF,Alici E,Guimarães F

    更新日期：2014-08-01 00:00:00

  • DRB1*03 diversity and DRB3 associations in five major population groups in the United States.

    abstract：:One hundred sixty-one DRB1*03 positive individuals from each of five U.S. population groups (Caucasoids, African Americans, Asians/Pacific Islanders, Hispanics, and Native Americans) were randomly selected from a database of 82,979 individuals. DRB1*03 alleles were identified by polymerase chain reaction-sequence-spec...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/s0198-8859(01)00379-2

    authors： Tang TF,Wang J,Slack R,Lin YS,Li L,Heine U,Ng J,Hartzman RJ,Katovich Hurley C

    更新日期：2002-03-01 00:00:00

  • In vitro model for the activation of CD4 and CD8 T cell receptors.

    abstract：:Previously, most models that sought to explain the misregulation of immune cell function assumed molecular similarities between the disease-causing pathogens and the host's proteins. In recent time several different models have been proposed and in this study, these concepts are compared to a new hypothesis proposing ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2009.05.010

    authors： Arneth BM

    更新日期：2009-09-01 00:00:00

  • Four tumor necrosis factor alpha genes polymorphisms and periodontitis risk in a Chinese population.

    abstract：BACKGROUND:Tumour necrosis factor-alpha (TNF-alpha) has been implicated in the pathogenesis of generalized aggressive periodontitis (AgP) and chronic periodontitis (CP). The objective of the present study was to evaluate the association of four TNF-alpha gene polymorphisms (-1031T/C, -857C/T, -308G/A and -238G/A) with ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2013.08.009

    authors： Yang W,Jia Y,Wu H

    更新日期：2013-12-01 00:00:00

  • FcεRI levels and frequencies of peripheral blood dendritic cell populations in allergic rhinitis.

    abstract：:The dendritic cell (DC) lineage encompasses a diverse population of cells with unique subtype-specific functions. In peripheral blood, four DC subsets have been identified based on their distinct expression of CD1c, CD141, CD16, and CD123, and these subpopulations exhibit functional properties in immune responses. How...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2010.07.008

    authors： Lundberg K,Greiff L,Borrebaeck CA,Lindstedt M

    更新日期：2010-10-01 00:00:00

  • Genetic diversity of HLA system in four populations from Baja California, Mexico: Mexicali, La Paz, Tijuana and rural Baja California.

    abstract：:We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in 250 Mexicans from the states of Baja California Norte and Baja California Sur living in Mexicali (N = 100), La Paz (N = 75), Tijuana (N = 25) and rural communities (N = 50) to obtain information regarding allelic and h...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2019.06.007

    authors： Escobedo-Ruíz A,Barquera R,González-Martín A,Argüelles-San Millán JM,Uribe-Duarte MG,Hernández-Zaragoza DI,Clayton S,Arrieta-Bolaños E,Ruíz-Corral MJ,Goné-Vázquez I,Arellano-Prado FP,Martínez-Álvarez JC,García-Arias VE,Rodrígue

    更新日期：2020-09-01 00:00:00

  • Emerging role of donor-specific anti-human leukocyte antigen antibody determination for clinical management after solid organ transplantation.

    abstract：:Preformed and de novo donor-specific HLA antibodies (DSA) have been associated with allograft dysfunction and failure. The application of solid-phase methods have increased the sensitivity and specificity of antibody detection; however the clinical significance of these DSA is under evaluation. In the present study, w...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2009.06.009

    authors： Zeevi A,Lunz JG 3rd,Shapiro R,Randhawa P,Mazariegos G,Webber S,Girnita A

    更新日期：2009-08-01 00:00:00

  • Detection of non-HLA-DR determinants by alloreactive lymphocyte clones.

    abstract：:Using the soft-agar colony assay, we have generated three MT3-associated clones: HJ1, HJ13, and HJ39, from an MLR combination of two unrelated individuals. Another clone, HJ37, appeared to recognize a novel HLA-D determinant. PLT inhibition studies with monoclonal anti-Ia-like antibodies (Mab) were conducted on clones...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(83)90066-6

    authors： Zeevi A,Annen K,Scheffel C,Duquesnoy RJ

    更新日期：1983-02-01 00:00:00

  • Use of complement regulators, CD35, CD46, CD55, and CD59, on leukocytes as markers for diagnosis of viral and bacterial infections.

    abstract：:Several complement regulatory proteins exist on self-cells to prevent damage by the serum complement system. In the present study, we aimed to perform quantitative analysis of membrane-bound complement regulators, CR1 (CD35), MCP (CD46), DAF (CD55), and MIRL (CD59), on peripheral blood neutrophils, monocytes, and lymp...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2013.01.011

    authors： Nuutila J,Jalava-Karvinen P,Hohenthal U,Kotilainen P,Pelliniemi TT,Nikoskelainen J,Lilius EM

    更新日期：2013-05-01 00:00:00

  • Monoclonal antibody definition of multiple polymorphic epitopes on human leukocyte antigen-DRw52.

    abstract：:Monoclonal antibodies have revealed complexity within the human leukocyte antigen class II antigens. We have studied epitopes present on a DR3 homozygous B-lymphoblastoid cell line using five polymorphic monoclonal antibodies produced and characterized in our laboratory. Serological analysis on a panel of B-cell lines...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(87)90107-8

    authors： Fuggle SV,Carter C,Watts F,Kirkley J,Morris PJ

    更新日期：1987-11-01 00:00:00

  • Association of polymorphic variants of IL-1β and IL-1RN genes in the development of Graves' disease in Kashmiri population (North India).

    abstract：PURPOSE:Graves' disease (GD) is a multigenic, organ specific autoimmune disorder with a strong genetic predisposition and IL-1β has been shown to be involved in its pathogenesis. The present study was aimed to determine the genetic associations between polymorphisms of IL-1β gene promoter region (-511 T>C) (rs16944), e...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2018.02.006

    authors： Shehjar F,Afroze D,Misgar RA,Malik SA,Laway BA

    更新日期：2018-04-01 00:00:00

  • Genetic susceptibility and anti-human platelet antigen 5b alloimmunization role of HLA class II and TAP genes.

    abstract：:Platelet alloimmunization may result in post-transfusion purpura, and during pregnancy may cause neonatal alloimmune thrombocytopenia (NAIT), with a frequency estimated at 1.3 per 1000 live births. The risk of morbidity is significant: 20% of affected infants have neurologic sequelae and the death rate is about 10%. A...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(96)00019-5

    authors： Semana G,Zazoun T,Alizadeh M,Morel-Kopp MC,Genetet B,Kaplan C

    更新日期：1996-04-01 00:00:00

  • Independence of measles-specific humoral and cellular immune responses to vaccination.

    abstract：:With a larger, independent cohort and more sophisticated measures, we sought to confirm our work that indicated independence of humoral and cellular immunity following measles vaccination. We recruited an age-stratified random cohort of 764 healthy subjects from all socioeconomic strata, all with medical-record docume...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2012.02.016

    authors： Jacobson RM,Ovsyannikova IG,Vierkant RA,Pankratz VS,Poland GA

    更新日期：2012-05-01 00:00:00

  • Matrix metalloproteinase-9 promoter polymorphisms in Korean patients with systemic lupus erythematosus.

    abstract：:To investigate the association between functional promoter polymorphisms of matrix metalloproteinase-9 (MMP-9) and systemic lupus erythematosus (SLE), we analyzed MMP-9 promoter -1562 C>T and MMP-9 -90 (CA)(n) repeat polymorphisms in 135 Korean SLE patients (mean age, 34.7 years; 124 female and 11 male) and in 135 gen...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2008.03.005

    authors： Lee YJ,Woo M,Nam JH,Baek J,Im CH,Lee EY,Lee EB,Park KS,Song YW

    更新日期：2008-06-01 00:00:00

  • Associations of MHC genes with levels of caries-inducing organisms and caries severity in African-American women.

    abstract：:The aim of this investigation was to evaluate the relationship between MHC alleles at the HLA-DRB1, DQB1 and TNFa microsatellite loci and levels of oral bacteria that play a role in the etiology of dental caries, and the DMFS index in 186 AA primparous women. The average age of the cohort was 20.8+/-3.7 years. The med...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/s0198-8859(99)00088-9

    authors： Acton RT,Dasanayake AP,Harrison RA,Li Y,Roseman JM,Go RC,Wiener H,Caufield PW

    更新日期：1999-10-01 00:00:00

  • Polymorphism of DRw52 and its association with DRw11 and DRw12 in South African blacks (Negroes) and individuals of mixed ancestry (Cape coloreds).

    abstract：:The HLA-DRB3 gene, which encodes the supertypic HLA-DRw52 antigen, has been shown to have limited polymorphism. The alleles at this locus are also in linkage disequilibrium with the alleles at the DRB1 locus. We have studied 16 DRw11 and three DRw12 haplotypes in the South African populations. Five of the DRw11,DQw7 h...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(90)90100-4

    authors： Martell RW,Oudshoorn M,Arendse B,du Toit ED

    更新日期：1990-05-01 00:00:00

  • Structurally based epitope analysis of major histocompatibility complex class I-related chain A (MICA) antibody specificity patterns.

    abstract：:Recent studies have suggested a clinical significance to the detection of anti-major histocompatibility complex class I-related chain A (MICA) antibodies in transplantation. We have developed an eplet-based version of the HLAMatchmaker algorithm to assess the epitope specificity of these antibodies. Molecular viewing ...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/j.humimm.2008.10.003

    authors： Duquesnoy RJ,Mostecki J,Hariharan J,Balazs I

    更新日期：2008-12-01 00:00:00

  • A method for using serum or plasma as a source of DNA for HLA typing.

    abstract：:A simple method for obtaining DNA from serum and plasma is described. Using appropriate primer pairs the polymorphic segments of HLA class II genes were amplified by the polymerase chain reaction (PCR) from this DNA, and typed using allele-specific oligonucleotide hybridization. When compared with DNA obtained from pe...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(92)90060-z

    authors： Martin M,Carrington M,Mann D

    更新日期：1992-02-01 00:00:00

  • B cells in chronic graft-versus-host disease.

    abstract：:Allogeneic hematopoietic stem cell transplantation (alloHCT) is the definitive therapy for numerous otherwise incurable hematologic malignancies and non-malignant diseases. The genetic disparity between donor and recipient both underpins therapeutic effects and confers donor immune system-mediated damage in the recipi...

    journal_title：Human immunology

    pub_type： 杂志文章,评审

    doi：10.1016/j.humimm.2019.03.003

    authors： McManigle W,Youssef A,Sarantopoulos S

    更新日期：2019-06-01 00:00:00

  • HLA-restricted immune response to mycobacterial antigens: relevance to vaccine design.

    abstract：:Identification of mycobacterial antigens that are recognized by CD4+ Th1 cells in HLA-nonrestricted manner or in association with multiple allelic products is required to develop universally effective vaccines against mycobacterial diseases. Our studies in this direction have shown that several recombinant mycobacteri...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/s0198-8859(99)00137-8

    authors： Mustafa AS

    更新日期：2000-02-01 00:00:00

  • Gm markers in celiac disease.

    abstract：:The association of Ig allotypes with celiac disease was analyzed in a sample of 95 Italian patients typed for HLA polymorphisms. No significant association was found for any Gm, A2m, or Km specificity when the overall sample was considered. However, significant different sex ratios were shown by patients' fnb positive...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(83)90065-4

    authors： Carbonara AO,DeMarchi M,van Loghem E,Ansaldi N

    更新日期：1983-02-01 00:00:00

  • Interaction of penicillin with HLA-A and -B antigens.

    abstract：:When lymphocytes of healthy donors were incubated with penicillin and washed before HLA typing, the cytotoxic reactivity of some typing sera with their corresponding antigen was blocked. When the penicillin was added to the cytotoxicity assay at different times, competition between penicillin and alloantiserum for bin...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(82)90033-7

    authors： Claas FH,Runia-van Nieuwkoop R,van den Berge W,van Rood JJ

    更新日期：1982-08-01 00:00:00

  • HLA-DR alpha, -DX alpha, and DR beta III gene association studies in DR3 individuals.

    abstract：:In this study we have examined the results of probing with synthetic oligomers at the DR beta III locus, together with restriction fragment length polymorphisms defined by BglII digestion and a cDNA DR alpha probe, and Taq 1 digestion and a genomic DQ alpha probe. We have demonstrated heterogeneity of the human leukoc...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(87)90018-8

    authors： Gorski J,Niven MJ,Sachs JA,Mach B,Cassell PG,Festenstein H,Awad J,Hitman GA

    更新日期：1987-12-01 00:00:00

  • HIV envelope protein is recognized as an alloantigen by human DR-specific alloreactive T cells.

    abstract：:Recent studies from this laboratory reported the mapping of the full profile of T-cell allorecognition regions of HLA-DR2 beta subunit. The results indicated the presence of an allodeterminant within DR2 beta regions 141-156. In another study, we have shown that this allodeterminant is one of five regions of structura...

    journal_title：Human immunology

    pub_type： 杂志文章

    doi：10.1016/0198-8859(92)90082-x

    authors： Atassi H,Atassi MZ

    更新日期：1992-05-01 00:00:00