Antiepileptic monotherapy significantly impairs normative scores on common tests of executive functions.

abstract：BACKGROUND:One of recent interesting hypotheses of transient global amnesia (TGA) pathophysiology is the preexisting vulnerability of the memory network in patients with TGA. AIM OF THE STUDY:To verify the hypothesis that patients with recurrent amnestic attacks may have more disrupted structural connectivity than pat...

journal_title：Acta neurologica Scandinavica

authors： Moon Y,Moon WJ,Han SH

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVES:To investigate efficacy and safety of entacapone across phase III studies in Parkinson's disease (PD) with wearing-off symptoms. METHODS:Retrospective, pooled analysis of four phase 3 randomized, double-blind, placebo-controlled studies with entacapone. RESULTS:475 of 808 patients with PD received entacapo...

journal_title：Acta neurologica Scandinavica

authors： Kuoppamäki M,Vahteristo M,Ellmén J,Kieburtz K

更新日期：2014-10-01 00:00:00

abstract：:Eighteen Swedish patients with familial amyloidotic polyneuropathy were tested for the met30 mutation of the transthyretin (TTR) (prealbumin) gene by RFLP analysis of genomic DNA using the restriction enzyme NsiI. The results confirmed previous findings that the Swedish variant of familial polyneuropathy has the same ...

journal_title：Acta neurologica Scandinavica

authors： Holmgren G,Lundgren E,Kangawa K,Kurihara T,Matsukura S,Matsuo H,Nakazato M,Steen L

更新日期：1993-02-01 00:00:00

abstract：OBJECTIVES:There are very few data available in the literature on the use of stiripentol in adults with Dravet syndrome (DS). DS cases are increasingly recognized in adulthood, and more children with DS now survive to adulthood. The aim of the study was to document the effectiveness and tolerability of stiripentol in a...

journal_title：Acta neurologica Scandinavica

authors： Balestrini S,Sisodiya SM

更新日期：2017-01-01 00:00:00

abstract：:The effect of methylprednisolone (MP) on neurologic recovery and spinal cord blood flow (SCBF) was investigated up to 4 days after a spinal cord compression injury in rats. The injury was produced at midthoracic level by applying a load of 35 g on a 2.2 x 5.0 mm compression plate for 5 min, which resulted in transient...

journal_title：Acta neurologica Scandinavica

authors： Holtz A,Nyström B,Gerdin B

更新日期：1990-07-01 00:00:00

abstract：OBJECTIVES:Stroke is associated with a higher risk of occult cancer. We studied the types of occult cancer most often associated with stroke. MATERIALS AND METHODS:All patients with incident stroke in Denmark 2003-2015 were identified through the Danish Stroke Registry (n = 85 893) and matched 1:10 on age and sex to t...

journal_title：Acta neurologica Scandinavica

authors： Tybjerg AJ,Babore AD,Olsen TS,Andersen KK

更新日期：2020-11-01 00:00:00

abstract：:Examinations with directional Doppler (DD) with 10 MHz transducer, and pulsed Doppler in combination with two-dimensional sector scanner with 3 MHz transducer (Duplex) were carried out on 100 vessels in 51 patients with transitory ischemic attacks (TIA) and minor stroke within the territory of the internal carotid art...

journal_title：Acta neurologica Scandinavica

authors： Zbornikova V,Akesson JA,Lassvik C

更新日期：1982-04-01 00:00:00

abstract：OBJECTIVES:To measure gait and postural stability by objective methods in spastic MS patients and to evaluate the effect of baclofen on gait and postural stability. PATIENTS AND METHODS:Fourteen spastic MS patients were examined in a placebo controlled double-blind, cross-over trial of oral baclofen treatment. The gai...

journal_title：Acta neurologica Scandinavica

authors： Orsnes GB,Sørensen PS,Larsen TK,Ravnborg M

更新日期：2000-04-01 00:00:00

abstract：:Over last fifty years, intravenous (iv) phenytoin (PHT) loading dose has been the treatment of choice for patients with benzodiazepine-resistant convulsive status epilepticus and several guidelines recommended this treatment regimen with simultaneous iv diazepam. Clinical studies have never shown a better efficacy of ...

journal_title：Acta neurologica Scandinavica

authors： Zaccara G,Giorgi FS,Amantini A,Giannasi G,Campostrini R,Giovannelli F,Paganini M,Nazerian P,Tuscany study group on seizures in the emergency department and status epilepticus in adults.

更新日期：2018-06-01 00:00:00

abstract：OBJECTIVE:Bilateral hippocampal abnormality is frequent in mesial temporal lobe sclerosis and might affect outcome in epilepsy surgery. The objective of this study was to compare the lateralization of interictal and ictal scalp EEG with MRI T2 relaxometry. MATERIAL AND METHODS:Forty-nine consecutive patients with intr...

journal_title：Acta neurologica Scandinavica

authors： Okujava M,Schulz R,Hoppe M,Ebner A,Jokeit H,Woermann FG

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:The Multiple Sclerosis Functional Composite (MSFC) is a multidimensional measurement tool for multiple sclerosis (MS) including a measure of ambulation (Timed 25-foot Walk [TWT]), arm function (Nine-Hole Peg Test [9HPT]) and cognition (Paced Auditory Serial Addition Test [PASAT]). OBJECTIVES:To assess the r...

journal_title：Acta neurologica Scandinavica

authors： Rosti-Otajärvi E,Hämäläinen P,Koivisto K,Hokkanen L

更新日期：2008-06-01 00:00:00

abstract：:Beta-2-microglobulin (beta 2m) levels were studied in the cerebrospinal fluid (CSF) and plasma of 52 patients with clinically definite multiple sclerosis (MS) and of 14 with aseptic meningo-encephalitis (AM). Reference values for beta 2m were defined in 72 subjects of different age groups with tension headache (TH). P...

journal_title：Acta neurologica Scandinavica

authors： Us O,Lolli F,Baig S,Link H

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:The Danish National Patient Register, Landspatientregistret (LPR), is a register of all hospital discharges and outpatient treatments in Denmark. AIMS:It is increasingly used in research so it is important to understand to what extent this can be used as an accurate source of information. Virtually all pati...

journal_title：Acta neurologica Scandinavica

authors： Mason K,Thygesen LC,Stenager E,Brønnum-Hansen H,Koch-Henriksen N

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:To clarify how chronic solvent abuse affects cognitive function using magnetic resonance imaging as an index of brain damage. MATERIAL AND METHODS:A total of 25 chronic solvent abusers underwent magnetic resonance imaging with quantitative neurometry and Wechsler Adult Intelligence Scales revised. RESULTS:T...

journal_title：Acta neurologica Scandinavica

authors： Yamanouchi N,Okada S,Kodama K,Sakamoto T,Sekine H,Hirai S,Murakami A,Komatsu N,Sato T

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVES:The GM2 gangliosidoses are a group of genetic disorders caused by the accumulation of ganglioside GM2 in neuronal cells. We examined the alpha- and beta-subunits of beta-hexosaminidases by a non-radioisotopes detecting system to evaluate whether it was a useful method for understanding of the pathophysiologi...

journal_title：Acta neurologica Scandinavica

authors： Utsumi K,Tsuji A,Kase R,Tanaka A,Tanaka T,Uyama E,Ozawa T,Sakuraba H,Komaba Y,Kawabe M,Iino Y,Katayama Y

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:For patients with medication refractory medial temporal lobe epilepsy (MTLE), surgery offers the hope of a cure. However, up to 30% of patients with MTLE continue to experience disabling seizures after surgery. The reasons why some patients do not achieve seizure freedom are poorly understood. A promising the...

journal_title：Acta neurologica Scandinavica

authors： Breedlove J,Nesland T,Vandergrift WA 3rd,Betting LE,Bonilha L

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:Post-stroke cognitive impairment (PSCI) occurs commonly and is linked with development of dementia. We investigated the relationship between demographic, clinical and stroke symptoms at stroke onset and the presence of PSCI at 1 and 3 years after stroke. METHODS:We accessed anonymized data from the Virtual ...

journal_title：Acta neurologica Scandinavica

authors： Arba F,Quinn T,Hankey GJ,Inzitari D,Ali M,Lees KR,VISTA Collaboration.

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:Analysis of the CTG-repeat number and three biallelic markers, Alu(+/-), HinfI(+/-), and TaqI(+/-), in the DMPK gene in healthy and myotonic dystrophy type 1 (DM1) Serbian individuals. Also, the consideration of haplotypes in the light of the proposed models of CTG-repeat evolution and origin of the DM1 muta...

journal_title：Acta neurologica Scandinavica

authors： Krndija D,Savić D,Mladenović J,Rakocević-Stojanović V,Apostolski S,Todorović S,Romac S

更新日期：2005-04-01 00:00:00

abstract：:Previously we have shown low levels of dystrophin immunoreactivity in muscle from patients with DMD. According to the "frame-shift hypothesis" DMD muscle should not synthesize any dystrophin through to the C-terminus and it has been suggested that the protein detected is not dystrophin, but a related autosomal homolog...

journal_title：Acta neurologica Scandinavica

authors： Nicholson LV,Johnson MA,Davison K,O'Donnell E,Falkous G,Barron M,Harris JB

更新日期：1992-07-01 00:00:00

abstract：:Vigabatrin (VGB), an irreversible inhibitor of gamma-aminobutyric acid (GABA) transaminase, is approved as adjunct treatment of refractory partial seizures as well as infantile spasms. Although VGB has been proven to be effective, its use is limited by the risk of retinopathy and associated peripheral visual field def...

journal_title：Acta neurologica Scandinavica

authors： Heim MK,Gidal BE

更新日期：2012-10-01 00:00:00

abstract：:3-methoxy-4-hydroxyphenylglycol (MHPG) and 5-hydroxyindoleacetic acid (5-HIAA) as well as homovanillic acid (HVA) and cyclic AMP were estimated in the morning urine of 41 drug-free parkinsonian patients and 25 hospitalized controls. In 29 patients, the estimations were repeated after 2 weeks treatment with L-dopa plus...

journal_title：Acta neurologica Scandinavica

authors： Markianos M,Hadjikonstantinou M,Bistolaki E

更新日期：1982-08-01 00:00:00

abstract：:63 patients with alcoholic-nutritional peripheral neuropathy were given neurologic, electrophysiologic and nutritional examinations. 24 of these patients were reexamined later in the course of their disease, after from 2 to 72 months (mean 33). Alcoholic-nutritional neuropathy appeared and worsened after bouts of heav...

journal_title：Acta neurologica Scandinavica

authors： Hawley RJ,Kurtzke JF,Armbrustmacher VW,Saini N,Manz H

更新日期：1982-11-01 00:00:00

abstract：:Twenty patients with paralysis agitans took part in a double-blind, cross-over investigation of CB 154 (2-bromo-alpha-ergocryptine) and Madopar (L-Dopa + benserazid (a peripheral decarboxylase inhibitor), dose ratio 4:1). Each treatment phase lasted for 8 weeks. Modapar was found to be significantly superior to CB 154...

journal_title：Acta neurologica Scandinavica

authors： Gerlach J

更新日期：1976-03-01 00:00:00

abstract：:Serum levels of the soluble interleukin-2 receptor (sIL-2R), an indicator of T cell activation, were significantly elevated in chronic progressive MS (CPMS) patients, clinically stable MS patients and in patients with other neurological diseases (OND) as compared to healthy controls. Levels of sIL-2R in steroid treate...

journal_title：Acta neurologica Scandinavica

authors： Bansil S,Troiano R,Cook SD,Rohowsky-Kochan C

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVES:We investigated whether mutation of mitochondrial DNA (mtDNA) affects the copy number of the mitochondrial genome in patients with mitochondrial myopathy encephalopathy with lactic acidosis and stroke-like episodes (MELAS) and those with myoclonic epilepsy with ragged-red fiber (MERRF) syndromes. MATERIALS ...

journal_title：Acta neurologica Scandinavica

authors： Liu CS,Cheng WL,Lee CF,Ma YS,Lin CY,Huang CC,Wei YH

更新日期：2006-05-01 00:00:00

abstract：:We investigated the types of syndrome, location, size and presumed causes of 72 patients with acute capsular lacunar infarction. Clinical syndromes were classified into pure motor hemiparesis (PM), sensorimotor stroke (SM) and ataxic hemiparesis (AH). Lesion sizes of AH were significantly smaller than those of PM (p <...

journal_title：Acta neurologica Scandinavica

authors： Tei H,Uchiyama S,Maruyama S

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Presence of mild cognitive impairment (MCI) as a predictor for Parkinson's disease dementia (PDD) has been discussed from a clinical perspective. Recently, a Movement Disorder Society (MDS) commissioned Task Force published guidelines for PD-MCI. However, long-term follow-ups of the PD-MCI guidelines for the...

journal_title：Acta neurologica Scandinavica

authors： Domellöf ME,Ekman U,Forsgren L,Elgh E

更新日期：2015-08-01 00:00:00

abstract：:A 23-year-old patient suffering from mental deterioration was referred for CT study following her first epileptic fit. The study disclosed generalized atrophy and diffuse symmetric white matter hypodensities. Similar findings were found in her 13-year-old retarded sister. The diagnosis of metachromatic leukodystrophy ...

journal_title：Acta neurologica Scandinavica

authors： Reider-Grosswasser I,Bornstein N

更新日期：1987-01-01 00:00:00

abstract：:To clarify the central nervous and the cardiovascular mechanisms mediating the Cushing response (CR) during intracranial hypertension, the effects of continuous and prolonged expansion of an epidural supratentorial balloon was studied in six dogs. Regional cerebral blood flow, cardiac output, extracerebral tissue bloo...

journal_title：Acta neurologica Scandinavica

authors： Schrader H,Hall C,Zwetnow NN

更新日期：1985-09-01 00:00:00

abstract：:Three Alzheimer's disease patients with Pisa syndrome were presented. These patients were treated with cholinesterase inhibitors within a post-marketing surveillance study. The clinical and pharmacological histories of these patients suggest a relation between cholinesterase inhibitors and the pleurothotonus. The diff...

journal_title：Acta neurologica Scandinavica

authors： Vanacore N,Suzzareddu G,Maggini M,Casula A,Capelli P,Raschetti R

更新日期：2005-03-01 00:00:00