Postischaemic regional microvascular variations in the porcine renal cortex.


:Regional microcirculatory differences in the superficial renal cortex were studied before and during 4 h following 60 min of renal ischaemia in seven pigs under continuous intravenous chlormethiazole-pancuronium anaesthesia. Superficial renal cortical blood flow (Qsrc) was measured by laser Doppler flowmetry (LDF) in two different regions. In two other different regions tissue oxygenation (PtO2) was measured by surface electrodes. Thus, microcirculatory measurements were simultaneously carried out in each animal in four different regions of the left kidney. After 60 min of renal ischaemia, pronounced renal cortical microcirculatory disturbances were found. The regional microcirculatory differences were notable, especially after ischaemia. On average, Qsrc was 49 +/- 11 (s.d.) arbitrary units at baseline and decreased to 24 +/- 4 arb. units 4 h after start of reperfusion (P less than 0.05). Before ischaemia the average difference between Qsrc simultaneously measured in two different parts of the renal cortex was 26 +/- 15% of the mean of both measurements, and it was 30 +/- 22% 4 h after start of reperfusion (n.s.). Mean PtO2 (m-PtO2) was on average 4.5 +/- 1.3 kPa at baseline and 2.4 +/- 1.5 kPa 4 h after start of reperfusion (P less than 0.05). The average difference between m-PtO2 simultaneously measured in two different parts of the renal cortex at baseline was 24 +/- 13% of the mean of both measurements and 57 +/- 49% 4 h after start of reperfusion (n.s.). In each of the two measured regions of the renal cortex m-PtO2 was calculated from 160 small tissue volumes distributed within a surface area of about 1 mm2.(ABSTRACT TRUNCATED AT 250 WORDS)


Sandin R,Feuk U,Modig J




Has Abstract


1991-08-01 00:00:00












  • The association between pre-operative sepsis and 30-day mortality in hip fracture patients-A cohort study.

    abstract:BACKGROUND:Post-operative sepsis considerably increases mortality, but the extent of pre-operative sepsis in hip fracture patients and its consequences are sparsely elucidated. The aim of this study was to assess the association between pre-operative sepsis and 30-day mortality after hip fracture surgery. METHODS:We c...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Mørch SS,Tantholdt-Hansen S,Pedersen NE,Duus CL,Petersen JA,Andersen CØ,Jarløv JO,Meyhoff CS

    更新日期:2018-10-01 00:00:00

  • Lactate levels predict mortality and need for peritoneal dialysis in children undergoing congenital heart surgery.

    abstract:BACKGROUND:The purpose of this study was to investigate whether an initial post-operative lactate level is a predictor of mortality, need for peritoneal dialysis (PD), duration of intubation or length of stay (LOS) in the intensive care unit (ICU) in children undergoing cardiac surgery. METHOD:A retrospective, observa...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Maarslet L,Møller MB,Dall R,Hjortholm K,Ravn H

    更新日期:2012-04-01 00:00:00

  • Socioeconomic status and risk of intensive care unit admission with sepsis.

    abstract:BACKGROUND:A recent study showed higher risk of bacteremia among individuals with low socioeconomic status (SES). We hypothesized that patients with a low SES have a higher risk of intensive care unit (ICU) admission with sepsis compared to patients with higher SES. METHODS:This was a case-control study on patients wi...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Storm L,Schnegelsberg A,Mackenhauer J,Andersen LW,Jessen MK,Kirkegaard H

    更新日期:2018-08-01 00:00:00

  • The effect of intranasally administered nitroglycerin on the blood pressure response to laryngoscopy and intubation in patients undergoing coronary artery by-pass surgery.

    abstract::The effect of intranasally administered nitroglycerin (NTG) on the cardiovascular response to laryngoscopy and intubation was studied. Thirty patients scheduled to undergo coronary artery by-pass surgery under thiopentone, enflurane and pancuronium anaesthesia were randomly divided into three groups. Group I received ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Dich-Nielsen J,Hole P,Lang-Jensen T,Owen-Falkenberg A,Skovsted P

    更新日期:1986-01-01 00:00:00

  • Hepatopulmonary syndrome: a concern for the anesthetist? Pre-operative evaluation of hypoxemic patients with liver disease.

    abstract::Liver cirrhosis and other chronic hepatic diseases are followed in a subset of affected patients by gas exchange abnormalities resulting from a syndrome called hepatopulmonary syndrome (HPS). The structural basis of this clinical entity is an alteration of pulmonary vasculature resulting in abnormal vasodilatation and...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,评审


    authors: Mazzeo AT,Lucanto T,Santamaria LB

    更新日期:2004-02-01 00:00:00

  • Addition of lidocaine to bupivacaine for spinal anaesthesia compared with bupivacaine spinal anaesthesia and local infiltration anaesthesia.

    abstract:BACKGROUND:Two spinal anaesthesia techniques were compared with local infiltration anaesthesia (LIA) to test the hypothesis that the addition of lidocaine to bupivacaine would decrease the spinal block's duration and provide shorter recovery to discharge. METHODS:Ninety-three patients undergoing outpatient herniorrhap...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,随机对照试验


    authors: Yazicioglu D,Akkaya T,Kulacoglu H

    更新日期:2013-11-01 00:00:00

  • Propofol and isoflurane induced EEG burst suppression patterns in rabbits.

    abstract::The aim of this study was to compare propofol produced EEG burst suppression with isoflurane produced burst suppression in rabbits and to see whether rabbits can serve as models in studying the effects of different anaesthetics on human EEG. We recorded EEG of eight rabbits anaesthetised with isoflurane and propofol. ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Hartikainen K,Rorarius M,Mäkelä K,Yli-Hankala A,Jäntti V

    更新日期:1995-08-01 00:00:00

  • Opioid use in cancer pain. Is a more liberal approach enhancing toxicity?

    abstract::The majority of cancer patients develop pain before death. This pain has been shown to be underdiagnosed and undertreated. Opioid use has increased in the past 20 years in both developing and developed countries. The changing pattern in opioid use has resulted in the emergence of neurotoxicity as a major side effect o...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,评审


    authors: Daeninck PJ,Bruera E

    更新日期:1999-10-01 00:00:00

  • An increased body mass index is no risk factor for postoperative nausea and vomiting. A systematic review and results of original data.

    abstract:BACKGROUND:An increased Body Mass Index (BMI) is almost always mentioned as a fundamental risk factor for postoperative nausea (PN), vomiting (PV) or both (PONV). However, multivariate analyses were unable to detect any correlation. Therefore, we asked whether an increased BMI is really a risk factor for PONV. METHODS...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,meta分析


    authors: Kranke P,Apefel CC,Papenfuss T,Rauch S,Löbmann U,Rübsam B,Greim CA,Roewer N

    更新日期:2001-02-01 00:00:00

  • Survival of female geriatric patients after hip fracture surgery. A comparison of 5 anesthetic methods.

    abstract::Female geriatric patients (mean age 80.9 years; n = 169) undergoing surgery for hip fracture were given epidural, neurolept analgesia, ketamine, enflurane or halothane anesthesia. The rate of survival in the different groups was studied up to 4 years after the operation and compared with the expected survival of norma...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Wickström I,Holmberg I,Stefánsson T

    更新日期:1982-12-01 00:00:00

  • Persistent opioid use and socio-economic factors: a population-based study in Norway.

    abstract:BACKGROUND:A growing proportion of the population is using opioids for longer time periods, but little is known about the characteristics of patients who are persistent opioid users. We therefore studied the association between socio-economic factors and persistent vs. short-term opioid use 4 years later. METHODS:The ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Svendsen K,Fredheim OM,Romundstad P,Borchgrevink PC,Skurtveit S

    更新日期:2014-04-01 00:00:00

  • Postoperative pain relief, from the patients' and the nurses' point of view.

    abstract:UNLABELLED:In this prospective, consecutive study, 191 patients were interviewed before and after surgery (orthopaedic, gynaecological, abdominal and urological operations) about their attitude to and the quality of received pain relief, respectively. In addition, nurses working in the surgical units involved in the st...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Juhl IU,Christensen BV,Bülow HH,Wilbek H,Dreijer NC,Egelund B

    更新日期:1993-05-01 00:00:00

  • Efficacy of simulation-based trauma team training of non-technical skills. A systematic review.

    abstract::Trauma resuscitation is a complex situation, and most organisations have multi-professional trauma teams. Non-technical skills are challenged during trauma resuscitation, and they play an important role in the prevention of critical incidents. Simulation-based training of these is recommended. Our research question wa...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,评审


    authors: Gjeraa K,Møller TP,Østergaard D

    更新日期:2014-08-01 00:00:00

  • Peroperative depth of anaesthesia may influence postoperative opioid requirements.

    abstract:BACKGROUND:Studies on monitoring the depth of anaesthesia have shown that with the use of these monitors the peroperative consumption of anaesthetics can be reduced. Studies have also indicated that the peroperative depth of anaesthesia may affect the postoperative course. The purpose of this study was to evaluate a po...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章


    authors: Henneberg SW,Rosenborg D,Weber Jensen E,Ahn P,Burgdorff B,Thomsen LL

    更新日期:2005-03-01 00:00:00

  • Depth of a central venous catheter tip: length of insertion guideline for pediatric patients.

    abstract:BACKGROUND:In pediatric patients, several studies have been undertaken to establish central venous catheter (CVC) tip optimal depth. Assessments of catheter tip position using chest radiographs may be misleading, whereas transesophageal echocardiography (TEE) has been shown to accurately monitor catheter tip placement ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Yoon SZ,Shin TJ,Kim HS,Lee J,Kim CS,Kim SD,Park CD

    更新日期:2006-03-01 00:00:00

  • Dexamethasone as adjuvant for femoral nerve block following knee arthroplasty: a randomized, controlled study.

    abstract:BACKGROUND:We examined the effect of the addition of dexamethasone to bupivacaine for femoral nerve blocks on the block duration and the quality of post-operative analgesia following total knee replacement surgery. METHODS:In total, 200 ASA I-III patients were randomly allocated to either the control group who receive...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 评论,杂志文章


    authors: Sherif AA,Elsersy HE

    更新日期:2016-08-01 00:00:00

  • Thoracic epidural analgesia via the lumbar approach using nerve stimulation in a pediatric patient with Down syndrome.

    abstract::This case illustrates the threading of an epidural catheter with electrical stimulation guidance from the lumbar epidural space to the thoracic space in a pediatric patient. A 17-year-old boy with Down syndrome, weighing 48 kg, was scheduled to undergo a laparotomy for duodenal obstruction and gastrostomy tube inserti...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Tsui BC,Entwistle L

    更新日期:2005-05-01 00:00:00

  • High-frequency oscillatory ventilation combined with intermittent mandatory ventilation in critically ill neonates and infants.

    abstract::We have evaluated the high-frequency oscillatory ventilation (HFOV) combined with intermittent mandatory ventilation (IMV) in critically ill neonates and infants using the Babylog 8000 SW 4.0. We used HFOV combined with IMV as a rescue mode in 10 neonates and infants aged 1 day to 17 months, who were receiving maximal...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Murthy BV,Petros AJ

    更新日期:1996-07-01 00:00:00

  • Ultrasonography reveals a high prevalence of lower spinal dysraphism in children with urogenital anomalies.

    abstract:BACKGROUND:Lower spinal dysraphism is frequently reported in anorectal anomaly combined with urogenital anomalies. The prevalence of the spinal dysraphism has not been comprehensively studied in children with simple urogenital anomalies. We evaluated the prevalence of the spinal dysraphism using ultrasound data of the ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Koo BN,Hong JY,Song HT,Kim JM,Kil HK

    更新日期:2012-05-01 00:00:00

  • Aerosolized surfactant reverses respiratory failure in lung-lavaged rats.

    abstract::The effects of surfactant replacement by aerosol inhalation and by bolus instillation were compared in rats with respiratory failure induced by repeated lung lavage. The rats were anesthetized with pentobarbital sodium and mechanically ventilated with 100% oxygen. The PaO2 of control rats not given surfactant (n = 9) ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Li WZ,Chen WM,Kobayashi T

    更新日期:1994-01-01 00:00:00

  • Hemodynamic effects of tracheal and intravenous adrenaline in infants with congenital heart anomalies.

    abstract:BACKGROUND:If intravenous access cannot be accomplished during cardiopulmonary resuscitation in children, tracheal administration of 100 micrograms/kg of adrenaline (ten times greater than the intravenous dose) is recommended. METHODS:In a randomized crossover study we recoreded the hemodynamic effect of a low dose of...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Jonmarker C,Olsson AK,Jögi P,Forsell C

    更新日期:1996-09-01 00:00:00

  • Epidural analgesia following upper abdominal surgery: United Kingdom practice.

    abstract:BACKGROUND:Epidural Analgesia (EA) may be used to provide pain relief after upper abdominal surgery. A variety of drugs and combinations may be used. Potential side effects lead some to believe EA should be restricted to high care areas. METHOD:The use of EA following upper abdominal surgery is surveyed in 214 hospita...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Cook TM,Eaton JM,Goodwin AP

    更新日期:1997-01-01 00:00:00

  • Effect of dexmedetomidine on the characteristics of bupivacaine in a caudal block in pediatrics.

    abstract:BACKGROUND:Dexmedetomidine (DEX) is a highly selective alpha(2)-adrenoceptor agonist that has been used increasingly in children. However, the effect of caudal DEX has not been evaluated before in children. This prospective randomized double-blinded study was designed to evaluate the analgesic efficacy of caudal DEX wi...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章,随机对照试验


    authors: Saadawy I,Boker A,Elshahawy MA,Almazrooa A,Melibary S,Abdellatif AA,Afifi W

    更新日期:2009-02-01 00:00:00

  • Laryngeal papillomatosis with airway obstruction in an infant.

    abstract::Laryngeal papillomatosis in infants and children is a benign condition, but the location and a marked tendency for recurrence makes the disease both dangerous and troublesome. This case report deals with a little girl who had suffered hoarseness and wheezing since she was born. The diagnosis of laryngeal papillomatosi...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Mikkelsen PG

    更新日期:2001-05-01 00:00:00

  • Pre-operative fasting guidelines: an update.

    abstract::Liberal pre-operative fasting routines have been implemented in most countries. In general, clear fluids are allowed up to 2 h before anaesthesia, and light meals up to 6 h. The same recommendations apply for children and pregnant women not in labour. In children <6 months, most recommendations now allow breast- or fo...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 指南,杂志文章,实务指引,评审


    authors: Søreide E,Eriksson LI,Hirlekar G,Eriksson H,Henneberg SW,Sandin R,Raeder J,(Task Force on Scandinavian Pre-operative Fasting Guidelines, Clinical Practice Committee Scandinavian Society of Anaesthesiology and Intensive Care Medicine).

    更新日期:2005-09-01 00:00:00

  • A comparison of glucose-free 2% lidocaine and hyperbaric 5% lidocaine for spinal anaesthesia.

    abstract::Fifty patients scheduled to undergo transurethral surgery of the bladder were allocated to receive spinal anaesthesia with either glucose-free 2% lidocaine (80 mg) or hyperbaric 5% lidocaine (80 mg). Onset time, cephalad spread of analgesia, duration of analgesia, duration and intensity of motor block, quality of anal...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Toft P,Bruun-Mogensen C,Kristensen J,Hole P

    更新日期:1990-02-01 00:00:00

  • Four years' treatment with ketamine and a trial of dextromethorphan in a patient with severe post-herpetic neuralgia.

    abstract::N-methyl-D-aspartate (NMDA) receptors are involved in the development of neuropathic pain. Ketamine, a non-competitive NMDA receptor antagonist, has in several case reports given pain relief but efficacy in dosages tolerated in long-term ketamine treatment is unknown. Another substance with an antagonist action at NMD...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Klepstad P,Borchgrevink PC

    更新日期:1997-03-01 00:00:00

  • Anesthesia-related mortality and morbidity over a 5-year period in 2,363,038 patients in Japan.

    abstract:BACKGROUND:Statistical data of mortality and morbidity related to anesthesia have not been reported in Japan since World War II. The need to comprehensively examine the events of cardiac arrest as well as mortality prompted the first national study in Japan. METHODS:Confidential questionnaires were sent to all Japan S...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Kawashima Y,Takahashi S,Suzuki M,Morita K,Irita K,Iwao Y,Seo N,Tsuzaki K,Dohi S,Kobayashi T,Goto Y,Suzuki G,Fujii A,Suzuki H,Yokoyama K,Kugimiya T

    更新日期:2003-08-01 00:00:00

  • Prediction of outcome from intensive care after gastroenterologic emergency.

    abstract::Prognostic factors determining the outcome from intensive care were studied in 952 patients admitted to 25 Finnish ICUs after gastroenterologic emergency. Logistic regression analysis was used to create predictive models based on the APACHE II-system. The models were constructed by using data from a random two-thirds ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Niskanen M,Kari A,Nikki P,Iisalo E,Kaukinen L,Rauhala V,Saarela E

    更新日期:1994-08-01 00:00:00

  • Anaphylactic reaction to patent blue V after sentinel lymph node biopsy.

    abstract:BACKGROUND:We report a documented grade III IgE-mediated hypersensitivity reaction associated with the use of 2.5% patent blue V dye for sentinel lymph node biopsy during breast cancer surgery. METHODS:Immediately after the reaction, when hemodynamic stability was obtained, plasma histamine was measured whereas serum ...

    journal_title:Acta anaesthesiologica Scandinavica

    pub_type: 杂志文章


    authors: Dewachter P,Mouton-Faivre C,Benhaijoub A,Abel-Decollogne F,Mertes PM

    更新日期:2006-02-01 00:00:00