Abstract:
OBJECTIVE:Correlation of muscle function, muscle mass and endurance, and exercise tolerance in chronic obstructive pulmonary disease (COPD). DESIGN:Sixteen COPD patients (forced expiratory volume during the first second 38 +/- 15% predicted) and 6 controls underwent magnetic resonance imaging of the thigh, muscle strength and endurance, and exercise tolerance assessments. RESULTS:Thigh mass distribution was bimodal (cutoff 19.0 kg m). Six COPD patients (16 +/- 2.5 kg m(-2)) (P < 0.05) presented reduced thigh mass (COPDLQ), whereas 10 patients with normal quadriceps mass (COPDNQ) and all controls had identical mass distribution (22 +/- 2.4 kg m(-2)). COPDLQ patients had lower muscle function and lower exercise tolerance than both COPDNQ and controls (P < 0.05 each), but muscle strength corrected by mass was similar between COPD patients (COPDLQ 0.59 +/- 0.12 and COPDNQ 0.55 +/- 0.10 Nm kg(-1) m(-2)) and controls (0.62 +/- 0.04 Nm Kg(-1) m(-2)). In contrast, endurance to muscle mass ratio was lower in COPD (COPDLQ and COPDNQ 0.91 +/- 0.15 and 0.89 +/- 0.15 J kg(-1) m(-2)) than in controls (1.07 +/- 0.11 J kg(-1) m(-2)) (P < 0.05). Half-time phosphocreatine recovery (COPDLQ 66 +/- 14 and COPDNQ 55 +/- 9 secs, not significant) was also slower than in controls (43 +/- 10 secs) (P < 0.01). CONCLUSIONS:Impaired muscle strength was explained by reduced muscle mass, but it did not account for abnormal muscle endurance. The latter seems associated to impaired O2 transport/O2 utilization, resulting in altered muscle bioenergetics.
journal_name
Am J Phys Med Rehabiljournal_title
American journal of physical medicine & rehabilitationauthors
Vilaro J,Rabinovich R,Gonzalez-deSuso JM,Troosters T,Rodríguez D,Barberà JA,Roca Jdoi
10.1097/PHM.0b013e31818dff86subject
Has Abstractpub_date
2009-01-01 00:00:00pages
39-46issue
1eissn
0894-9115issn
1537-7385journal_volume
88pub_type
杂志文章abstract::The purpose of this study was to examine electrophysiologic abnormalities, including motor-evoked potentials, in a patient with post-traumatic syringomyelia before and after syringopleural shunting. A patient with C5 quadriplegia presented with pain, ascending sensory loss, and new weakness in the left upper extremity...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199012000-00006
更新日期:1990-12-01 00:00:00
abstract:OBJECTIVE:To examine changes in functional status and health-related quality of life (HRQOL) during inpatient stroke rehabilitation to examine the associations between changes in the two measures. DESIGN:Two independently collected databases were combined for a retrospective analysis. One contained the objectively ass...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/01.phm.0000240666.24142.f7
更新日期:2006-10-01 00:00:00
abstract::Clostridium difficle has been associated with diarrhea in hospitalized patients receiving antibiotic therapy and may be nosocomially acquired. Rehabilitation hospital inpatients may require frequent antibiotic intervention and are thus at risk, although few reports of epidemics at such centers have been published. Thi...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199204000-00008
更新日期:1992-04-01 00:00:00
abstract:OBJECTIVE:There is little information regarding the effect of aerobic exercise on physical and neuromotor performance in older adults. The aim of this randomized, controlled trial was to determine the effects of a 12-wk aerobic exercise program on functional and neuromotor performance in inactive healthy older adults. ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1097/01.phm.0000179479.30543.1c
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine the correlations between objective performance-based physical function, self-reported physical function, quality of life, and gait function at 1 mo after unilateral total knee arthroplasty. DESIGN:Cross-sectional data from 195 patients who underwent unilateral primary t...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000001222
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to examine whether receipt of testosterone replacement therapy was associated with reduced 30-day rehospitalization after postacute care among older men with testosterone deficiency. DESIGN, PATIENTS, AND METHODS:We conducted a retrospective cohort study using a 5% national sample of...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000001127
更新日期:2019-06-01 00:00:00
abstract::Musculoskleletal conditions comprise the second most common reason for physician visits and have the greatest negative impact on health-related quality of life in the industrialized world. Therefore, all medical schools should provide education for their students in these disorders. Physiatrists play a unique role in ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0b013e3181b72a3e
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:Assess the effectiveness of intramuscular electrical stimulation in reducing hemiplegic shoulder pain at 12 mos posttreatment. DESIGN:A total of 61 chronic stroke survivors with shoulder pain and subluxation participated in this multiple-center, single-blinded, randomized clinical trial. Treatment subjects r...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/01.phm.0000184154.01880.72
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to evaluate the short-term physiologic effects of respiratory muscle training with normocapnic hyperpnea added to standard exercise training on respiratory muscle endurance/strength and exercise tolerance in patients with chronic obstructive pulmonary disease. DESIGN:The study used a...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/PHM.0000000000000988
更新日期:2018-12-01 00:00:00
abstract::This paper describes the conceptual basis for the development of a new clinical evaluation instrument, the Tufts Assessment of Motor Performance (TAMP). The TAMP is a 32-item, diagnosis-independent, criterion-referenced test that samples physical performance items in the areas of mobility, activities of daily living a...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-198810000-00003
更新日期:1988-10-01 00:00:00
abstract::The steady state profiles of 63 men with traumatic spinal cord injuries (24 quadriplegics and 39 paraplegics; average age of 31.2 +/- 6.8 yr; 18-44 yr) were studied. The average length of post-traumatic period was 6.2 +/- 5.0 yr, ranging from 8 months to 20 yr. It was found that all the subjects had normal serum thyro...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199212000-00004
更新日期:1992-12-01 00:00:00
abstract:OBJECTIVE:To investigate the relation between protein expression changes in the cerebellum and improvement of motor coordination in rats with cerebral infarction. DESIGN:The rat group with treadmill training (n = 10) were compared with the rat group without treadmill training (n = 10) after 2.5 hrs of transient middle...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0b013e3181b3323b
更新日期:2010-02-01 00:00:00
abstract::A case is presented of a 53-yr-old ambulatory ventilator-dependent individual who demonstrated that functional ambulation could be possible with a modified rolling walker. The patient used intermittent positive pressure ventilation delivered by noninvasive methods 24 h a day. For potentially ambulatory ventilator user...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199210000-00011
更新日期:1992-10-01 00:00:00
abstract:OBJECTIVE:The current study was designed to document clinical and ultrasound (US) findings of patients with residual limb pain (RLP) after amputation and to investigate the relationship between these findings. MATERIALS AND METHODS:A chart review was performed to identify demographic and clinical data including the ag...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000000687
更新日期:2017-08-01 00:00:00
abstract::This study explores the "higher order" cognitive abilities of conceptual reasoning, problem solving, mental flexibility, and efficiency in 36 adolescents with spina bifida. The subjects, age 10 to 23 years, were assessed on a set of neuropsychological measures, and an individual profile analysis was conducted. All sub...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199805000-00011
更新日期:1998-05-01 00:00:00
abstract::Thromboembolic obstruction of the brachiocephalic artery can have significant functional consequences because it threatens arterial circulation to the right upper limb and right cerebrum. A case is presented of a young man who sustained right basal ganglia infarct 2 mo after suffering multiple gunshot wounds to his ch...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199901000-00016
更新日期:1999-01-01 00:00:00
abstract::The physiatrist can now be instrumental in prolonging the survival of individuals with neuromuscular disease by using respiratory muscle aids. As a result, morbidity and mortality from cardiomyopathy are likely to increase for patients with generalized myopathies. One hundred consecutive patients with dystrophin-defic...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-09-01 00:00:00
abstract:OBJECTIVE:We investigated the correlation between movement patterns, measured by polyelectromyography (PEMG), and clinical motor manifestations in children with cerebral palsy. DESIGN:Subjects included 53 children with spastic cerebral palsy (diplegic [n = 43] and quadriplegic [n = 10] groups) and 18 normal children. ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/01.PHM.0000078180.72129.5C
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:To examine the clinical utility of two brief assessment tools, the Wechsler Abbreviated Scale of Intelligence (WASI) and the Hopkins Verbal Learning Test-Revised (HVLT-R). We hypothesized that these measures would predict continued need for supervision and functional outcome at discharge. DESIGN:In this retr...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-200203000-00011
更新日期:2002-03-01 00:00:00
abstract::Exercised rats have larger myelinated nerve fibers than sedentary rats and exercised rats with acrylamide neuropathy have smaller fibers than acrylamide-treated sedentary rats. These nerve fiber changes were the result of work hypertrophy and overwork atrophy, respectively. This study was designed to reassess morpholo...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-198904000-00004
更新日期:1989-04-01 00:00:00
abstract::A 17-item questionnaire was designed to assess the relative importance of various factors to physical medicine and rehabilitation (PM&R) training directors when ranking PM&R resident applicants during the National Resident Match. The questionnaire was sent to all PM&R residency training directors. The recipients were ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199406000-00002
更新日期:1994-06-01 00:00:00
abstract::.As the life expectancy of individuals with spina bifida increases, a lifelong need for management of many health issues in a rehabilitation setting has emerged in recent years. Physiatrists, in consultation with a variety of adult specialists, are particularly well suited to manage the common musculoskeletal, skin, b...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,评审
doi:10.1097/PHM.0b013e31818de070
更新日期:2008-12-01 00:00:00
abstract::A 20-yr-old active duty soldier complained of right lateral forearm numbness that began shortly after carrying 100 lbs of equipment (20-lb load-bearing equipment, 20-lb individual body armor, and 60-lb rucksack) while deployed during Operation Iraqi Freedom. Physical examination revealed normal strength but decreased ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0b013e3181837b83
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:Stroke is an acute neurologic dysfunction of vascular origin, characterized by loss of voluntary movement, sensory disturbances, and neurologic findings in the contralateral half of the body. Acute and long-term complications because of immobilization are seen in all organ systems. The aim of this study was t...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1097/00002060-200108000-00009
更新日期:2001-08-01 00:00:00
abstract::Topical formulations of diclofenac, a nonsteroidal anti-inflammatory drug commonly prescribed to treat musculoskeletal complaints such as osteoarthritis, low back pain, and myofascial pain, are available in the form of a solution, gel, and patch. The topical application of diclofenac results in substantially lower sys...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000000172
更新日期:2014-11-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the effects of an aquatic exercise program designed to enhance muscular strength in paretic lower limbs in subacute stroke patients. METHOD:Thirty-six subacute stroke patients were randomly divided to a conventional or an aquatic group (n = 18 each). Outcome measures were ...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1097/PHM.0000000000000512
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the impact of power assist wheels on the distance traveled by manual wheelchair users and analyze potential cofactors in the magnitude of response and to test the hypothesis that wheelers would travel significantly further with power assist wheels. DESIGN:A 16-wk A (Preintervention)-B (Interventi...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0b013e3181e72286
更新日期:2010-08-01 00:00:00
abstract::The purpose of this study was to stimulate the laryngeal cough reflex using a nebulized, mild chemical irritant and to record an associated laryngeal evoked potential from the internal branch of the superior laryngeal nerve. The laryngeal evoked potential was obtained on ten normal subjects from the right internal bra...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-199811000-00014
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the relationship between a clinical test of ankle plantarflexor strength and ankle power generation (APG) at push-off during walking. DESIGN:This is a prospective cross-sectional study of 102 patients with traumatic brain injury. OUTCOME MEASURES:Handheld dynamometry...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/PHM.0000000000000196
更新日期:2015-02-01 00:00:00
abstract::Given the rarity of sural nerve mononeuropathy, this retrospective study reports 20 cases observed during the last 12 yr, with some cases having especially unusual mechanisms of the nerve lesion. Five of the 20 cases were considered S1 root disease until electrodiagnostic findings. In the 14 other cases, the nerve les...
journal_title:American journal of physical medicine & rehabilitation
pub_type: 杂志文章
doi:10.1097/00002060-200211000-00014
更新日期:2002-11-01 00:00:00