Expression of fragile-X in a female fetus diagnosed after chorionic villus sampling.

Abstract:

:Study of different tissues of an aborted female fetus showed similar levels of fragile-X expression (6.3-9.2 per cent) and of early replication of the FRAXA-positive cells (50-66 per cent) in fetal tissues. Different culture media did not significantly affect either investigation. It is suggested that the distribution of X-inactivation in FRAXA-positive chorionic villus cells of a female fetus might indicate her future phenotype.

journal_name

Prenat Diagn

journal_title

Prenatal diagnosis

authors

Webb T

doi

10.1002/pd.1970110510

subject

Has Abstract

pub_date

1991-05-01 00:00:00

pages

333-8

issue

5

eissn

0197-3851

issn

1097-0223

journal_volume

11

pub_type

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