Abstract:
:Calcium functions as a secondary messenger within the cytosols of eukaryotes. This serves as a reference point to evaluate three related questions:Exploration of these three interrelated questions indicates the importance of more sensitive techniques and of a refined concept of information transfer and transduction. 1. Calcium, as well as cyclic AMP, also functions as a paracrine messenger; how specific and extensive is this use? 2. Calcium binding proteins and calcium extrusion mechanisms have been identified in prokaryotes; does it function as a messenger? 3. The concentrations of other divalent cations, especially zinc and magnesium, are well regulated and perturbations have specific physiological impacts; are these divalents involved in information transfer? Exploration of these three interrelated questions indicates the importance of more sensitive techniques and of a refined concept of information transfer and transduction.
journal_name
J Inorg Biochemjournal_title
Journal of inorganic biochemistryauthors
Permyakov EA,Kretsinger RHdoi
10.1016/j.jinorgbio.2008.09.006subject
Has Abstractpub_date
2009-01-01 00:00:00pages
77-86issue
1eissn
0162-0134issn
1873-3344pii
S0162-0134(08)00221-3journal_volume
103pub_type
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journal_title:Journal of inorganic biochemistry
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journal_title:Journal of inorganic biochemistry
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journal_title:Journal of inorganic biochemistry
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journal_title:Journal of inorganic biochemistry
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journal_title:Journal of inorganic biochemistry
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
doi:10.1016/j.jinorgbio.2007.09.007
更新日期:2008-02-01 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
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journal_title:Journal of inorganic biochemistry
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
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journal_title:Journal of inorganic biochemistry
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
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更新日期:2017-12-01 00:00:00
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journal_title:Journal of inorganic biochemistry
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
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更新日期:2012-02-01 00:00:00
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journal_title:Journal of inorganic biochemistry
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更新日期:2015-06-01 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
doi:10.1016/j.jinorgbio.2015.04.006
更新日期:2015-12-01 00:00:00
abstract::Vanadium compounds exert various insulin-mimetic and anti-diabetic effects both in vitro and in vivo. Vanadium(III, IV, V)-chlorodipicolinate (Vdipic-Cl) compounds, including H[V(III)(dipic-Cl)2]·5H2O (V3dipic-Cl), V(IV)O(dipic-Cl)(H2O)2 (V4dipic-Cl) and K[V(V)O2(dipic-Cl)] (V5dipic-Cl), were synthesized with the indi...
journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
doi:10.1016/j.jinorgbio.2014.03.011
更新日期:2014-07-01 00:00:00
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journal_title:Journal of inorganic biochemistry
pub_type: 杂志文章
doi:10.1016/j.jinorgbio.2011.02.006
更新日期:2011-05-01 00:00:00
abstract::Two macrocycles (1 and 2) are prepared that incorporate pendent groups in macrocycle 3 (3=1-oxa-4,7,10-triazacyclododecane) with the goal of studying the effect of these pendent groups on metal ion complexation, solution chemistry and catalysis. Zn(1) contains a macrocyclic ligand with a pendent acridine group and Zn(...
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