An intriguing association between dental and mental pathology in addicted and control subjects: a cross-sectional survey.


BACKGROUND:Recent clinical studies suggest that substance use may be associated with an acceleration of the ageing process, possibly related to a deficit of stem cell number or function. As this clinic had access to both medical and drug dependent patients, we tested the hypothesis that there may be an association between previously identified deficits. METHODS:A cross-sectional survey was performed looking at both dental and mental dysfunction. Both a dental index (DI) and a mental index (MI) were defined as previously described and utilised as summary measures of such pathology. FINDINGS:From 249 substance use disorder (SUD) and 134 general medical controls (N-SUD), 248 and 91 patients were selected with ages less than 57 years as the primary focus of analysis. The mean (+/- S.D.) ages (32.59 +/- 7.98 vs 35.65 +/- 15.45 years) were similar. The DI was found to correlate with the MI in a significant manner in SUD (R = 0.14, p = 0.03), N-SUD (R = 0.27, p = 0.009) and in the whole group (R = 0.17, p = 0.001). The (univariate) association of MI with DI (p = 0.019) and DI with MI (p = 0.0037) remained highly significant at multivariate regression after adjustment for psychiatric diagnoses and measures of dose-duration exposure to common addictive drugs. The qualitative appearance of the surfaces of best fit for the relationship between age, DI and MI was different in the two groups. CONCLUSIONS:These results suggest that the robust statistical association between dental and mental pathology may be related to common underlying pathophysiological mechanisms such as a progeroid or stem cell deficiency process in clinical addiction.


Br Dent J


British dental journal


Reece AS




Has Abstract


2008-12-13 00:00:00














  • Dental care and dentistry practice in the Medieval Medical School of Salerno.

    abstract::Even though dental care is sometimes erroneously considered a modern practice, written records from major ancient civilisation all around the world date back to several millennia BC. In particular, in the Middle Ages, among the tenth and thirteenth centuries, the illustrious Medical School of Salerno in Italy, the mos...

    journal_title:British dental journal

    pub_type: 历史文章,杂志文章


    authors: Bifulco M,Amato M,Gangemi G,Marasco M,Caggiano M,Amato A,Pisanti S

    更新日期:2016-07-22 00:00:00

  • Cost effectiveness modelling of a 'watchful monitoring strategy' for impacted third molars vs prophylactic removal under GA: an Australian perspective.

    abstract:OBJECTIVE:To develop a national level cost model of both the direct and indirect costs of hospitalisations for impacted teeth in Australia. This model will then be used to compare a watchful monitoring strategy for impacted third molars versus prophylactic removal under GA, and calculate possible cost savings in the sc...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Anjrini AA,Kruger E,Tennant M

    更新日期:2015-07-10 00:00:00

  • The turning point.

    abstract::A great number of dentists recognise the conflict between running a viable business and providing dental care to the same level they had been taught as students. This Personal View recounts the experiences of one general dental practitioner, but the feelings expressed have a universality that many will recognise. ...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Cheetham D

    更新日期:1994-02-19 00:00:00

  • The quality of orthodontic practice websites.

    abstract:OBJECTIVE:To evaluate orthodontic practice websites for the reliability of information presented, accessibility, usability for patients and compliance to General Dental Council (GDC) regulations on ethical advertising. SETTING:World Wide Web. MATERIALS AND METHODS:The term 'orthodontic practice' was entered into thre...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Parekh J,Gill DS

    更新日期:2014-05-01 00:00:00

  • Gabriel-Philippe de la Hire and the discovery of Hunter-Schreger bands.

    abstract::Hunter-Schreger bands are an optical phenomenon observed in mammalian tooth enamel. Familiar to all current and former students of dental histology, this optical phenomenon appears as alternating patterns of dark and light bands when cut enamel is viewed under reflected light. The discovery of this important feature o...

    journal_title:British dental journal

    pub_type: 传,历史文章,杂志文章


    authors: Lynch CD,McGillycuddy CT,O'Sullivan VR,Sloan AJ

    更新日期:2010-11-01 00:00:00

  • Perception of studying dental law and ethics among postgraduate dental students in the UK.

    abstract::Law and ethics is an integral part of medical and dental professional practice. The subject is touched upon in the undergraduate curriculum. Historically, dentists interested in postgraduate study in this subject have accessed courses on medical law and ethics. While there are areas of shared interest (for example, co...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Wassif HS

    更新日期:2015-08-14 00:00:00

  • A study of letters between general dental practitioners and consultant orthodontists.

    abstract::A survey was undertaken involving 268 general dental practitioners and 13 orthodontic consultants to determine the content of letters passed between them. There was good agreement between the two sets of respondents as to the appropriate contents of a letter. The feature of a letter least valued by both dentists and c...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Hammond M,Evans DR,Rock WP

    更新日期:1996-04-06 00:00:00

  • Early years postgraduate learning and training in prosthodontic dentistry: 2019 and beyond.

    abstract::The intended outcome of dental education is to produce dental clinicians who have the knowledge, technical skills, personal attributes, values and professional outlook to deliver the highest level of patient care. Due to the development and improvement of dental materials and clinical techniques, combined with a stead...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Movahedi S,Eliyas S,Fisher N

    更新日期:2019-05-01 00:00:00

  • Repair vs replacement of failed restorations in general dental practice: factors influencing treatment choices and outcomes.

    abstract:OBJECTIVE:To investigate the impact of repair vs replacement of failed restorations on patient related outcome measures, and to explore the clinical factors that influence this decision. DESIGN:Multicentre, prospective practice-based study. SETTING:Dental practices within Salford, Trafford and East Lancashire in the ...

    journal_title:British dental journal

    pub_type: 杂志文章,多中心研究


    authors: Javidi H,Tickle M,Aggarwal VR

    更新日期:2015-01-01 00:00:00

  • Is digit sucking of significance?

    abstract::A brief review of the literature of digit sucking is followed by the report of a study of 68 treated Class II division 1 malocclusions, designed to attempt to clarify the significance of digit sucking in their aetiology. Case histories of two of the patients from the study are briefly discussed to illustrate the range...

    journal_title:British dental journal

    pub_type: 杂志文章,评审


    authors: Brenchley ML

    更新日期:1991-12-07 00:00:00

  • A survey of patients seen in consultant clinics in conservative dentistry at Edinburgh Dental Hospital in 1990.

    abstract::A baseline study of referrals by letter to a department of conservative dentistry staffed purely by honorary consultants was conducted for one year. Distinct differences were found between the majority of patients referred from general practice and those referred from other sources. Principal reasons for referral were...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Callis PD,Charlton G,Clyde JS

    更新日期:1993-02-06 00:00:00

  • Dental composite depth of cure with halogen and blue light emitting diode technology.

    abstract:OBJECTIVES:To test the hypothesis that a blue light emitting diode (LED) light curing unit (LCU) can produce an equal dental composite depth of cure to a halogen LCU adjusted to give an irradiance of 300 mWcm-2 and to characterise the LCU's light outputs. MATERIALS AND METHODS:Depth of cure for three popular composite...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Mills RW,Jandt KD,Ashworth SH

    更新日期:1999-04-24 00:00:00

  • Are anterior occlusal radiographs indicated to supplement panoramic radiography during an orthodontic assessment?

    abstract::Five hundred pairs of dental panoramic tomographs (DPT) and maxillary anterior occlusal radiographs (AO) from patients referred to the orthodontic department of a dental teaching hospital were examined to assess the diagnostic yield from a panoramic radiograph of the premaxillary region alone and then assess the addit...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Taylor NG,Jones AG

    更新日期:1995-11-25 00:00:00

  • Fundamentals of prosthetic practice. Part I--The laboratory.

    abstract::Prosthetic dentistry in general practice produces many challenges for both the newly qualified trainee and the long-standing practitioner. If these challenges are not appreciated, met and dealt with effectively, the dentist may be left disillusioned with his skills and expertise, and stressed at the thought of treatin...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Welfare RD,Wright SM

    更新日期:1989-10-07 00:00:00

  • Clinical examination & record-keeping: Part 1: Dental records.

    abstract::This article forms part of a BDJ series of Practice papers on the subject of clinical examination and related record keeping. The series is taken from the Faculty of General Dental Practice UK (FGDP[UK]) 2016 Good Practice Guidelines book on this topic, edited by A. M. Hadden. This particular article, the first in the...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Hadden AM,and the FGDP(UK) Clinical Examination and Record-Keeping Working Group.

    更新日期:2017-11-24 00:00:00

  • Transitioning patients from teeth to implants.

    abstract::One major obstacle to treatment with implants is the transitional phase between a tooth supported occlusion and an implant supported occlusion. This is of particular concern when a patient with a failing dentition has not worn a removable prosthesis before and is planning to have a reconstruction supported by implants...

    journal_title:British dental journal

    pub_type: 杂志文章,评审


    authors: Jivraj S,Chee W

    更新日期:2006-12-09 00:00:00

  • Our hygienist will see you for your check-up now...

    abstract::Feasibility study: Assessing the efficacy and social acceptability of using dental hygienist-therapists as front-line clinicians. ...

    journal_title:British dental journal

    pub_type: 杂志文章



    更新日期:2016-12-09 00:00:00

  • The pattern of splint usage in the management of two common temporomandibular disorders. Part III: Long-term follow-up in an assessment of splint therapy in the management of disc displacement with reduction and pain dysfunction syndrome.

    abstract:OBJECTIVE:To assess the long-term follow-up of patients successfully treated for disc displacement with anterior repositioning splint therapy and patients successfully treated for pain dysfunction syndrome with stabilisation therapy. DESIGN:Retrospective analysis. SETTING:Dental school clinic unit. METHODS:Maintenan...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Davies SJ,Gray RJ

    更新日期:1997-10-25 00:00:00

  • The role of dental therapists working in four personal dental service pilots: type of patients seen, work undertaken and cost-effectiveness within the context of the dental practice.

    abstract:OBJECTIVES:To describe the type of patients seen and work undertaken by dental therapists employed in four personal dental service practices and to report on their cost-effectiveness within the context of the dental practice. METHOD:All members of the dental team used a standard day sheet to record all patient contact...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Harris R,Burnside G

    更新日期:2004-10-23 00:00:00

  • Destructive membranous periodontal disease (ligneous periodontitis): a case report and 3 years follow-up.

    abstract::Destructive membranous periodontal disease is a rare, destructive and poorly defined entity, which is the part of a systemic disease due to plasminogen deficiency and fibrin deposition. The disease is characterised by gingival enlargement and periodontal tissue destruction that leads to rapid tooth loss despite treatm...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Baykul T,Bozkurt Y

    更新日期:2004-10-23 00:00:00

  • Participant recruitment to FiCTION, a primary dental care trial - survey of facilitators and barriers.

    abstract:OBJECTIVE:To identify reasons behind a lower than expected participant recruitment rate within the FiCTION trial, a multi-centre paediatric primary dental care randomised controlled trial (RCT). SUBJECTS (MATERIALS) AND METHODS:An online survey, based on a previously published tool, consisting of both quantitative and...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Keightley A,Clarkson J,Maguire A,Speed C,Innes N

    更新日期:2014-11-01 00:00:00

  • Bone remodelling.

    abstract::Bone is a specialised connective tissue that, together with cartilage, makes up the skeleton. These tissues serve three functions: (a) mechanical support and site of muscle attachment for locomotion; (b) protection for vital organs and bone marrow and (c) a metabolic reserve of ions for the entire organism, especially...

    journal_title:British dental journal

    pub_type: 杂志文章,评审


    authors: Meghji S

    更新日期:1992-03-21 00:00:00

  • Review: the use of sodium hypochlorite in endodontics--potential complications and their management.

    abstract::Aqueous sodium hypochlorite (bleach) solution is widely used in dental practice during root canal treatment. Although it is generally regarded as being very safe, potentially severe complications can occur when it comes into contact with soft tissue. This paper discusses the use of sodium hypochlorite in dental treatm...

    journal_title:British dental journal

    pub_type: 杂志文章,评审


    authors: Spencer HR,Ike V,Brennan PA

    更新日期:2007-05-12 00:00:00

  • Advances in orthodontic anchorage with the use of mini-implant techniques.

    abstract::Orthodontic mini-implants (OMIs) represent a new form of anchorage provision and appear to provide a variety of benefits for both anchorage-demanding and complex orthodontic cases. This paper reports the latest perspectives on OMIs in terms of the emerging clinical evidence base coupled with their varied clinical appl...

    journal_title:British dental journal

    pub_type: 杂志文章,评审


    authors: Cousley RR,Sandler PJ

    更新日期:2015-02-16 00:00:00

  • Quality development.

    abstract::The problem with improving quality in dental practice is not so much a difficulty with understanding exactly what quality means, but more a lack of clear guidance as to how to take the simple, practical steps to achieving that improvement in the daily pressures of practice life. This article describes Quality Developm...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Grace M

    更新日期:1992-11-07 00:00:00

  • Medical emergencies in general dental practice in Great Britain. Part 3: Perceptions of training and competence of GDPs in their management.

    abstract:OBJECTIVES:To ascertain the training received in management of medical emergencies recalled by general dental practitioners (GDPs), as undergraduates and since graduation, to examine how well prepared they felt to manage such events and how their readiness might be improved. DESIGN:Postal questionnaire survey of a ran...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Atherton GJ,McCaul JA,Williams SA

    更新日期:1999-03-13 00:00:00

  • Characteristics of patients attending for cognitive behavioural therapy at one UK specialist unit for dental phobia and outcomes of treatment.

    abstract:AIM:To describe the characteristics of patients attending a psychologist-led cognitive behavioural therapy (CBT) service for individuals with dental phobia and the outcomes of treatment. METHOD:Analysis of routinely collected assessment and outcome data from 130 patients attending a single secondary service providing ...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Kani E,Asimakopoulou K,Daly B,Hare J,Lewis J,Scambler S,Scott S,Newton JT

    更新日期:2015-11-27 00:00:00

  • Dental caries in 12-year-old children and the effectiveness of dental services in Salford, UK in 1960, 1988 and 1997.

    abstract:OBJECTIVE:To investigate the dental health of 12-year-old children and the effectiveness of dental services in 1997 and compare the results with studies carried out in 1960 and 1988. BASIC RESEARCH DESIGN:Analytical survey using a one in five random sample of children in all seven secondary schools in Salford UK. Stan...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Whittle KW,Whittle JG

    更新日期:1998-04-25 00:00:00

  • Exploring dentists' professional behaviours reported in United Kingdom newspaper media.

    abstract::Aim Stories of dentists and their professional behaviours can be communicated around the world through news media. This may influence people's perceptions of dentistry and their trust in professionals. The aim of this study was to explore reports of dentists and their professional behaviours in newspaper media.Method ...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Ellis M,Johnson I

    更新日期:2020-08-27 00:00:00

  • Successful web searching.

    abstract::This section of the series introduces the topic of WWW search engines and directory sites; showing you how to find information using a search engine and a directory. It also covers other ways of searching for information on the internet. ...

    journal_title:British dental journal

    pub_type: 杂志文章


    authors: Downes PK

    更新日期:1998-10-24 00:00:00