Comparison between bispectral index and patient state index as measures of the electroencephalographic effects of sevoflurane.

Abstract:

BACKGROUND:The Bispectral Index (BIS) and the Patient State Index (PSI) quantify depth of anesthesia by analyzing the electroencephalogram. The authors examined the response of BIS and PSI to sevoflurane anesthesia. METHODS:In 22 patients, sevoflurane anesthesia was induced by inhalation with a tight-fitting facemask and was maintained via a laryngeal mask. Sevoflurane concentrations were increased until burst suppression occurred and subsequently decreased until BIS recovered to values above 60. This procedure was repeated twice until patients underwent intubation for subsequent surgery. End-tidal sevoflurane concentrations, BIS, and PSI were recorded simultaneously. The performance of PSI and BIS to predict the estimated sevoflurane effect site concentration, as derived from simultaneous pharmacokinetic and pharmacodynamic modeling, was compared by determination coefficients (rho(2)) and prediction probabilities (P(K)). RESULTS:A significant (P < 0.001) correlation between BIS and PSI was found (r(2) = 0.75), and a close sigmoid relation between sevoflurane effect site concentration and both BIS (rho(2) = 0.84 +/- 0.09) and PSI (rho(2) = 0.85 +/- 0.15) was observed. The maximum sevoflurane electroencephalographic effect resulted in PSI values (1.3 +/- 4.3) that were significantly (P = 0.019) lower than BIS values (7.9 +/- 12.1), and the effect site efflux constant k(e0) was significantly smaller (P = 0.001) for PSI (0.13 +/- 0.08 min(-1)) than for BIS (0.24 +/- 0.15 min(-1)). The probability of BIS (P(K) = 0.80 +/- 0.11) to predict sevoflurane effect site concentration did not differ (P = 0.76) from that of PSI (P(K) = 0.79 +/- 0.09). CONCLUSIONS:The BIS reacted faster to changes in sevoflurane concentrations, whereas the PSI made better use of the predefined index range. However, despite major differences in their algorithms and minor differences in their dose-response relations, both PSI and BIS predicted depth of sevoflurane anesthesia equally well.

journal_name

Anesthesiology

journal_title

Anesthesiology

authors

Soehle M,Ellerkmann RK,Grube M,Kuech M,Wirz S,Hoeft A,Bruhn J

doi

10.1097/ALN.0b013e3181895fd0

subject

Has Abstract

pub_date

2008-11-01 00:00:00

pages

799-805

issue

5

eissn

0003-3022

issn

1528-1175

pii

00000542-200811000-00011

journal_volume

109

pub_type

杂志文章
  • Emulsified isoflurane enhances thermal transient receptor potential vanilloid-1 channel activation-mediated sensory/nociceptive blockade by QX-314.

    abstract:BACKGROUND:QX-314 produces nociceptive blockade, facilitated by permeation through transient receptor potential vanilloid-1 (TRPV1) channels. TRPV1 channel can be activated by noxious heat and sensitized by volatile anesthetics. The authors hypothesized that emulsified isoflurane (EI) could enhance thermal TRPV1 channe...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0000000000000236

    authors: Zhou C,Liang P,Liu J,Zhang W,Liao D,Chen Y,Chen X,Li T

    更新日期:2014-08-01 00:00:00

  • Brain bioenergetics during cardiopulmonary resuscitation in dogs.

    abstract::Cardiac arrest causes a rapid loss of cerebral adenosine triphosphate [corrected] (ATP) and a decrease in cerebral intracellular pH (pHi). Depending on the efficacy of cardiopulmonary resuscitation (CPR), cerebral blood flow levels (CBF) ranging from near zero to near normal have been reported experimentally. Using 31...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199201000-00012

    authors: Eleff SM,Schleien CL,Koehler RC,Shaffner DH,Tsitlik J,Halperin HR,Rogers MC,Traystman RJ

    更新日期:1992-01-01 00:00:00

  • Impaired nociception and peripheral opioid antinociception in mice lacking both kinin B1 and B2 receptors.

    abstract:BACKGROUND:Kinins (e.g., bradykinin) acting through the constitutively expressed B2 and the injury-induced B1 receptors are involved in pain and hyperalgesia, as previously shown by use of receptor-selective antagonists and single-receptor knockout models. Because the overall contribution of kinins to painful processes...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0b013e318242b2ea

    authors: Cayla C,Labuz D,Machelska H,Bader M,Schäfer M,Stein C

    更新日期:2012-02-01 00:00:00

  • Propofol: relation between brain concentrations, electroencephalogram, middle cerebral artery blood flow velocity, and cerebral oxygen extraction during induction of anesthesia.

    abstract:BACKGROUND:The potential benefit of propofol dose regimens that use physiologic pharmacokinetic modeling to target the brain has been demonstrated in animals, but no data are available on the rate of propofol distribution to the brain in humans. This study measured the brain uptake of propofol in humans and the simulta...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000542-200212000-00006

    authors: Ludbrook GL,Visco E,Lam AM

    更新日期:2002-12-01 00:00:00

  • Anesthesia for thoracoscopic laser ablation of bullous emphysema.

    abstract:BACKGROUND:We describe the anesthetic management for a new surgical procedure: laser ablation of emphysematous bullae via thoracoscope. Although thoracoscopy is not new, this is the first description of a series of patients with bilateral, chronic lung disease who underwent long periods of one-lung ventilation (OLV) du...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199301000-00008

    authors: Barker SJ,Clarke C,Trivedi N,Hyatt J,Fynes M,Roessler P

    更新日期:1993-01-01 00:00:00

  • Isoflurane provides long-term protection against focal cerebral ischemia in the rat.

    abstract:BACKGROUND:Long-term neuroprotection by isoflurane has been questioned. The authors examined factors in experimental models potentially critical to definition of enduring isoflurane neuroprotection. METHODS:Rats were prepared for temporary middle cerebral artery occlusion (MCAO). Pericranial normothermia was maintaine...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200701000-00017

    authors: Sakai H,Sheng H,Yates RB,Ishida K,Pearlstein RD,Warner DS

    更新日期:2007-01-01 00:00:00

  • Optimization of the radioimmunoassays for measuring fentanyl and alfentanil in human serum.

    abstract::Measurement of serum fentanyl and alfentanil concentrations by radioimmunoassay (RIA) may result in significant errors and high variability when the technique described in the available fentanyl and alfentanil RIA kits is used. The authors found a 29-94% overestimation of measured fentanyl and alfentanil serum levels ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198409000-00010

    authors: Schüttler J,White PF

    更新日期:1984-09-01 00:00:00

  • Vaporized perfluorocarbon improves oxygenation and pulmonary function in an ovine model of acute respiratory distress syndrome.

    abstract:BACKGROUND:Perfluorocarbon liquids are being used experimentally and in clinical trials for the treatment of acute lung injury. Their resemblance to inhaled anesthetic agents suggests the possibility of application by vaporization. The authors' aim was to develop the technical means for perfluorocarbon vaporization and...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199908000-00021

    authors: Bleyl JU,Ragaller M,Tschö U,Regner M,Kanzow M,Hübler M,Rasche S,Albrecht M

    更新日期:1999-08-01 00:00:00

  • Bupivacaine-induced cardiac arrhythmias in sheep.

    abstract::Controversy persists about the cardiac toxicity of bupivacaine if accidentally administered intravenously during regional anesthesia. Using awake, unanesthetized sheep, we evaluated the cardiac effects of low and high equivalent doses of lidocaine and bupivacaine given intravenously over 10 s. All animals convulsed wi...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198401000-00004

    authors: Kotelko DM,Shnider SM,Dailey PA,Brizgys RV,Levinson G,Shapiro WA,Koike M,Rosen MA

    更新日期:1984-01-01 00:00:00

  • On-demand rather than daily-routine chest radiography prescription may change neither the number nor the impact of chest computed tomography and ultrasound studies in a multidisciplinary intensive care unit.

    abstract:BACKGROUND:Elimination of daily-routine chest radiographs (CXRs) may influence chest computed tomography (CT) and ultrasound practice in critically ill patients. METHODS:This was a retrospective cohort study including all patients admitted to a university-affiliated intensive care unit during two consecutive periods o...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/01.anes.0000296069.00566.16

    authors: Kröner A,Binnekade JM,Graat ME,Vroom MB,Stoker J,Spronk PE,Schultz MJ

    更新日期:2008-01-01 00:00:00

  • Intrathecal adenosine: interactions with spinal clonidine and neostigmine in rat models of acute nociception and postoperative hypersensitivity.

    abstract:BACKGROUND:Spinal adenosine receptor agonists exert antinociception in animal models of acute and chronic pain, but adenosine itself has not been examined. The authors tested the antinociceptive and antihypersensitivity interactions of intrathecal adenosine and its interactions with intrathecal clonidine and neostigmin...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199905000-00026

    authors: Chiari AI,Eisenach JC

    更新日期:1999-05-01 00:00:00

  • Hemodynamic responses to mechanical ventilation with PEEP: the effect of hypervolemia.

    abstract::The hemodynamic effects of prolonged mechanical ventilation with positive end-expiratory pressure (PEEP), with and without blood volume augmentation, were studied in 18 beagles anesthetized with halothane (0.7 per cent end-tidal). Addition of 12 cm H2O PEEP during mechanical ventilation in normavolemic dogs was associ...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-197501000-00009

    authors: Qvist J,Pontoppidan H,Wilson RS,Lowenstein E,Laver MB

    更新日期:1975-01-01 00:00:00

  • Effect of oxygen treatment on heart rate after abdominal surgery.

    abstract:BACKGROUND:Cardiac complications are common during the postoperative period and may be associated with hypoxemia and tachycardia. Preliminary studies in high-risk patients after operation have shown a possible beneficial effect of oxygen therapy on arterial oxygen saturation and heart rate. METHODS:The authors studied...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-199902000-00008

    authors: Rosenberg-Adamsen S,Lie C,Bernhard A,Kehlet H,Rosenberg J

    更新日期:1999-02-01 00:00:00

  • Performance of anesthetic depth indexes in rabbits under propofol anesthesia: prediction probabilities and concentration-effect relations.

    abstract:BACKGROUND:The permutation entropy, the approximate entropy, and the index of consciousness are some of the most recently studied electroencephalogram-derived indexes. In this work, a thorough comparison of these indexes was performed using propofol anesthesia in a rabbit model. METHODS:Six rabbits were anesthetized w...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0b013e318222ac02

    authors: Silva A,Campos S,Monteiro J,Venâncio C,Costa B,Guedes de Pinho P,Antunes L

    更新日期:2011-08-01 00:00:00

  • Predicting patient nonappearance for surgery as a scheduling strategy to optimize operating room utilization in a veterans' administration hospital.

    abstract:BACKGROUND:Previous attempts at improving operating room utilization have generally emphasized more accurate scheduling, starting the first case on time, and reducing turnover time. Surgical case cancellations have largely been ignored except for recommendations for preoperative screening and good physician-patient com...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200604000-00029

    authors: Basson MD,Butler TW,Verma H

    更新日期:2006-04-01 00:00:00

  • The effect of isoflurane-induced hypotension on cerebral blood flow and cerebral metabolic rate for oxygen in humans.

    abstract::Deliberate hypotension was induced with isoflurane (mean inspired concentration 2.3 +/- 1.0%) in 12 patients undergoing craniotomy for clipping of cerebral aneurysms. Global cerebral blood flow (CBF) was measured before, during, and after hypotension. Arterio-venous O2 content difference was measured concomitantly, an...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198603000-00001

    authors: Newman B,Gelb AW,Lam AM

    更新日期:1986-03-01 00:00:00

  • Pharmacokinetics, neuromuscular effects, and biodisposition of 3-desacetylvecuronium (Org 7268) in cats.

    abstract::The pharmacokinetics, biodisposition, and neuromuscular blocking properties of 3-desacetylvecuronium were studied in 17 adult cats. Animals were divided into three groups: five cats with kidney failure induced by bilateral ligation of the renal pedicles, six cats with galactosamine-induced fulminant hepatitis, and six...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199106000-00013

    authors: Segredo V,Shin YS,Sharma ML,Gruenke LD,Caldwell JE,Khuenl-Brady KS,Agoston S,Miller RD

    更新日期:1991-06-01 00:00:00

  • Phenylephrine added to prophylactic ephedrine infusion during spinal anesthesia for elective cesarean section.

    abstract:BACKGROUND:Because ephedrine infusion (2 mg/min) does not adequately prevent spinal hypotension during cesarean delivery, the authors investigated whether adding phenylephrine would improve its efficacy. METHODS:Thirty-nine parturients with American Society of Anesthesiologists physical status I-II who were scheduled ...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-200109000-00020

    authors: Mercier FJ,Riley ET,Frederickson WL,Roger-Christoph S,Benhamou D,Cohen SE

    更新日期:2001-09-01 00:00:00

  • Ventilator-associated pneumonia leading to acute lung injury after trauma: importance of Haemophilus influenzae.

    abstract:BACKGROUND:Ventilator-associated pneumonia is a clear risk factor for acute lung injury which has been poorly described in trauma patients. This prospective study was undertaken to estimate the incidence of such ventilator-associated pneumonia leading to acute lung injury, the risk factors, and the associated morbidity...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200602000-00006

    authors: Stéphan F,Mabrouk N,Decailliot F,Delclaux C,Legrand P

    更新日期:2006-02-01 00:00:00

  • Propofol decreases myofilament Ca2+ sensitivity via a protein kinase C-, nitric oxide synthase-dependent pathway in diabetic cardiomyocytes.

    abstract:BACKGROUND:The authors' objective was to assess the role of protein kinase C (PKC) and nitric oxide synthase (NOS) in mediating the effects of propofol on diabetic cardiomyocyte contractility, intracellular free Ca2+ concentration ([Ca2+]i), and myofilament Ca2+ sensitivity. METHODS:Freshly isolated ventricular myocyt...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200605000-00014

    authors: Wickley PJ,Shiga T,Murray PA,Damron DS

    更新日期:2006-05-01 00:00:00

  • Single-dose Antibiotic Prophylaxis in Regional Anesthesia: A Retrospective Registry Analysis.

    abstract:BACKGROUND:Catheter-related infection is a serious complication of continuous regional anesthesia. The authors tested the hypothesis that single-dose antibiotic prophylaxis is associated with a lower incidence of catheter-related infections. METHODS:Our analysis was based on cases in the 25-center German Network for R...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0000000000001218

    authors: Bomberg H,Krotten D,Kubulus C,Wagenpfeil S,Kessler P,Steinfeldt T,Standl T,Gottschalk A,Stork J,Meissner W,Birnbaum J,Koch T,Sessler DI,Volk T,Raddatz A

    更新日期:2016-09-01 00:00:00

  • Cerebral extracellular glucose and lactate concentrations during and after moderate hypoxia in glucose- and saline-infused rats.

    abstract::To assess the effect of a glucose infusion on brain extracellular fluid (ECF) during systemic hypoxia, changes in glucose and lactate concentrations in cerebral ECF during and after moderate hypoxic hypoxia were measured in adult, conscious, unrestrained rats, with a microdialysis probe in the posterior hippocampus. T...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199210000-00017

    authors: Harada M,Okuda C,Sawa T,Murakami T

    更新日期:1992-10-01 00:00:00

  • Women have the same desflurane minimum alveolar concentration as men: a prospective study.

    abstract:BACKGROUND:Women generally report greater sensitivity to pain than do men, and healthy young women require 20% more anesthetic than healthy age-matched men to prevent movement in response to noxious electrical stimulation. In contrast, minimum alveolar concentration (MAC) for xenon is 26% less in elderly Japanese women...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章

    doi:10.1097/00000542-200311000-00010

    authors: Wadhwa A,Durrani J,Sengupta P,Doufas AG,Sessler DI

    更新日期:2003-11-01 00:00:00

  • No evidence for blood flow redistribution with isoflurane or halothane during acute coronary artery occlusion in fentanyl-anesthetized dogs.

    abstract::The present study examines the postulate that isoflurane, in contrast to halothane, causes redistribution of blood flow away from an ischemic myocardial region through vasodilation of adjacent normally perfused myocardium. The study was performed in open-chest dogs anesthetized with fentanyl; ischemia was induced by o...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-199111000-00018

    authors: Moore PG,Kien ND,Reitan JA,White DA,Safwat AM

    更新日期:1991-11-01 00:00:00

  • Local anesthetic properties of prenylamine.

    abstract:BACKGROUND:Local anesthetics that produce analgesia of long duration with minimal impairment of autonomic functions are highly desirable for pain management in the clinic. Prenylamine is a known calcium channel blocker, but its local anesthetic blocking effects on voltage-gated sodium channels have not been studied thu...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200111000-00025

    authors: Mujtaba MG,Gerner P,Wang GK

    更新日期:2001-11-01 00:00:00

  • Detecting awareness in children by using an auditory intervention.

    abstract:BACKGROUND:The incidence of awareness has been reported to be higher in children than in adults. Accurately assessing awareness in children is difficult, and the lack of a specific measure of awareness makes it difficult to determine exactly how many and why children are aware. The aim of this study was to determine th...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/ALN.0b013e3181862a20

    authors: Davidson AJ,Sheppard SJ,Engwerda AL,Wong A,Phelan L,Ironfield CM,Stargatt R

    更新日期:2008-10-01 00:00:00

  • Effect of pretreatment with intrathecal excitatory amino acid receptor antagonists on the development of pain behavior caused by plantar incision.

    abstract:BACKGROUND:Drugs that block spinal excitatory amino acid receptor activation may prevent pain after surgery. The authors previously studied the effect of excitatory amino acid receptor antagonists after incision. In the present study, we examined the role of N-methyl-d-aspartate (NMDA), non-NMDA, and metabotropic gluta...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-200008000-00029

    authors: Pogatzki EM,Zahn PK,Brennan TJ

    更新日期:2000-08-01 00:00:00

  • Effect of cricoid pressure on the success of endotracheal intubation with a lightwand.

    abstract:BACKGROUND:The lightwand may be useful as an alternative for tracheal intubation during a rapid-sequence induction of anesthesia in the presence of a full stomach. This study was undertaken to assess the effect of application of cricoid pressure on the success of lightwand intubation. METHODS:Sixty adult female patien...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-200102000-00015

    authors: Hodgson RE,Gopalan PD,Burrows RC,Zuma K

    更新日期:2001-02-01 00:00:00

  • Comparison of enflurane, halothane, and isoflurane for diagnostic and therapeutic procedures in children with malignancies.

    abstract::The authors performed a randomized, prospective trial comparing enflurane, halothane, and isoflurane (each administered with nitrous oxide) to establish which inhaled anesthetic produced the fewest complications and the most rapid induction of anesthesia for children undergoing general anesthesia for diagnostic proced...

    journal_title:Anesthesiology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00000542-198512000-00015

    authors: Fisher DM,Robinson S,Brett CM,Perin G,Gregory GA

    更新日期:1985-12-01 00:00:00

  • Effects of isoflurane on cerebral autoregulation in dogs.

    abstract::The effect of decreased cerebral perfusion pressure (CPP) on regional cerebral blood flow (CBF) with radiolabeled microspheres in dogs receiving either 1.4% or 2.8% isoflurane following anesthesia induction with thiopental (12 mg/kg, iv bolus) was studied. Mean arterial blood pressure (MABP), cerebrospinal fluid press...

    journal_title:Anesthesiology

    pub_type: 杂志文章

    doi:10.1097/00000542-198810000-00008

    authors: McPherson RW,Traystman RJ

    更新日期:1988-10-01 00:00:00