Performance evaluation of ultrasonic Nakagami image in tissue characterization.

Abstract:

:Conventional ultrasonic B-mode images qualitatively describe tissue structures but are unsuitable for quantitative analyses of scatterer properties. We have recently developed an ultrasonic parametric imaging technique based on the Nakagami statistical distribution that is able to quantify scatterer concentrations. The aim of the present study is to further explore both the behavior of a Nakagami image in characterizing different scatterer structures at different signal-to-noise ratios (SNRs) and the feasibility of Nakagami imaging using a general commercial ultrasound scanner for tissue examinations. Simulations, experiments on a tissue-mimicking phantom and in vitro measurements on a muscle tissue before and after microwave treatment were carried out. The SNR and contrast-to-noise ratio (CNR) were estimated to quantify image performance. The results demonstrate that a Nakagami image can differentiate different scatterer concentrations for single, hypoechoic and hyperechoic targets. Also, a Nakagami image, when combined with an ultrasound scanner, can complement the B-scan to characterize tissue and to identify the region of interest with a larger CNR. However, the noise effect can degrade the performance of a Nakagami image. When the signal SNR decreased to 15 dB in simulations and to 8 dB in experiments, the CNR of the hyperechoic Nakagami image decreased by 4% and 27%, respectively, and that of the hypoechoic one decreased by 42% and 80%, respectively. These results indicate that a Nakagami image behaves well in identifying regions with high scatterer concentrations but does not perform well when both the scatterer concentration and SNR are low.

journal_name

Ultrason Imaging

journal_title

Ultrasonic imaging

authors

Tsui PH,Yeh CK,Chang CC,Chen WS

doi

10.1177/016173460803000202

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

78-94

issue

2

eissn

0161-7346

issn

1096-0910

journal_volume

30

pub_type

杂志文章
  • Improved Fourier-transform-based parallel receive beam formation.

    abstract::A Fourier transform (FT)-based technique for forming parallel receive beams has been previously employed to increase the imaging frame rate in ultrasonic imaging. However, the image quality in FT-based parallel reconstruction is degraded because differences in range focusing delays are ignored and a wide transmit beam...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173460302500201

    authors: Li ML,Li PC

    更新日期:2003-04-01 00:00:00

  • Shielding of piezoelectric ultrasonic probes in Hall effect imaging.

    abstract::This paper addresses significant sources of electromagnetic noise in Hall effect imaging. Hall effect imaging employs large electrical pulses for signal generation and high sensitivity ultrasonic probes for signal reception. Coherent noise arises through various coupling mechanisms between the excitation pulse and the...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469802000305

    authors: Wen H,Bennett E,Wiesler DG

    更新日期:1998-07-01 00:00:00

  • A quantitative approach to speckle reduction via frequency compounding.

    abstract::Coherent speckle is a source of image noise in ultrasonic B-mode imaging. The use of multiple imaging frequencies has been suggested as a technique for speckle contrast reduction. This technique involves the averaging of images whose speckle patterns have been modified by a change in the spectrum of the transmitted or...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173468600800301

    authors: Trahey GE,Allison JW,Smith SW,von Ramm OT

    更新日期:1986-07-01 00:00:00

  • An adaptive approach to computing the spectrum and mean frequency of Doppler signals.

    abstract::Modern ultrasound Doppler systems are facing the problem of processing increasingly shorter data sets. Spectral analysis of the strongly nonstationary Doppler signal needs to shorten the analysis window while maintaining a low variance and high resolution spectrum. Color flow imaging requires estimation of the Doppler...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469501700101

    authors: Herment A,Giovannelli JF

    更新日期:1995-01-01 00:00:00

  • Variance and covariance of accumulated displacement estimates.

    abstract::Tracking large deformations in tissue using ultrasound can enable the reconstruction of nonlinear elastic parameters, but poses a challenge to displacement estimation algorithms. Such large deformations have to be broken up into steps, each of which contributes an estimation error to the final accumulated displacement...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/0161734613479246

    authors: Bayer M,Hall TJ

    更新日期:2013-04-01 00:00:00

  • Autoregressive spectral estimation in ultrasonic scatterer size imaging.

    abstract::An autoregressive (AR) spectral estimation method was considered for the purpose of estimating scatterer size images. The variance and bias of the resulting estimates were compared with those using classical FFT periodograms for a range of input signal-to-noise ratios and echo-signal durations corresponding to various...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469601800102

    authors: Chaturvedi P,Insana MF

    更新日期:1996-01-01 00:00:00

  • Subharmonic contrast microbubble signals for noninvasive pressure estimation under static and dynamic flow conditions.

    abstract::Our group has proposed the concept of subharmonic aided pressure estimation (SHAPE) utilizing microbubble-based ultrasound contrast agent signals for the noninvasive estimation of hydrostatic blood pressures. An experimental system for in vitro SHAPE was constructed based on two single-element transducers assembled co...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173461103300301

    authors: Halldorsdottir VG,Dave JK,Leodore LM,Eisenbrey JR,Park S,Hall AL,Thomenius K,Forsberg F

    更新日期:2011-07-01 00:00:00

  • Digital simulation of pulsed ultrasonic waveforms.

    abstract::When modeling or simulating an ultrasonic pulse-echo system it is necessary to know the transducer waveforms that are the input to the system. In general, accurate transducer modeling is complex and waveform calculation is computationally intensive. Because of this, investigators often assume these waveforms to be sim...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173468700900405

    authors: Barber FE,Goodsitt MM

    更新日期:1987-10-01 00:00:00

  • Time reversal focusing applied to lithotripsy.

    abstract::Time reversal of ultrasonic field allows a very efficient approach to focusing pulsed ultrasonic waves through lossless inhomogeneous media. Time reversal mirrors (TRM) are made of large transducer arrays, allowing the incident acoustic field to be sampled, time reversed and re-emitted. Time reversal processing permit...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章,评审

    doi:10.1177/016173469601800202

    authors: Thomas JL,Wu F,Fink M

    更新日期:1996-04-01 00:00:00

  • An efficient motion estimation and compensation method for ultrasound synthetic aperture imaging.

    abstract::This paper describes a method for overcoming motion artifacts in synthetic aperture imaging. The method is based on a computer simulation study on the influence of target motion on synthetic aperture techniques. A region-based motion compensation approach is used in which only the axial motion is estimated and compens...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173460202400202

    authors: Kim KS,Hwang JS,Jeong JS,Song TK

    更新日期:2002-04-01 00:00:00

  • Computerized quantification analysis of left ventricular wall motion from echocardiograms.

    abstract::Two-dimensional echocardiography (2-D echo) imaging is a more attractive clinical tool than other modalities that either involve radiation exposure or are too slow to image heart motion in real-time. Computer-aided analysis of left ventricular(LV) wall motion provides quantitative parameters for diagnosis. This study ...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469701900204

    authors: Chen T,Chen TP,Tsai LM

    更新日期:1997-04-01 00:00:00

  • A comparison method for mean frequency estimators for Doppler ultrasound.

    abstract::Mean frequency estimators as used in pulsed Doppler ultrasound equipment should provide an accurate (quality) and consistent (robustness) estimate over a wide range of signal conditions. In a simplified signal model, the main parameters to consider are the noise level, mean frequency, bandwidth and power of both the D...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469201400404

    authors: Brands PJ,Hoeks AP

    更新日期:1992-10-01 00:00:00

  • Adaptive texture feature extraction with application to ultrasonic image analysis.

    abstract::Computer texture analysis methods use texture features that are traditionally chosen from a large set of fixed features known in literature. These fixed features are often not specifically designed to the problem at hand, and as a result they may have low discriminative power, and/or may be correlated. Increasing the ...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章,评审

    doi:10.1177/016173469802000204

    authors: Huisman HJ,Thijssen JM

    更新日期:1998-04-01 00:00:00

  • Transducer characterization from pressure amplitude distribution measurements using a Kalman filter as parameter estimation algorithm.

    abstract::The amplitude and frequency contents of a received ultrasound pulse depends on the spatial pressure amplitude distribution of the sound field, as produced by the transducer in the medium, and on the position and orientation of the reflecting surface in this field. Often, the geometry of the reflecting surface and the ...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469001200405

    authors: Linssen FM,Hoeks AP

    更新日期:1990-10-01 00:00:00

  • Linear arrays for vibro-acoustography: a numerical simulation study.

    abstract::In this work, we study linear array beamforming for vibro-acoustography systems. The goal of this research is to assess the feasibility of vibro-acoustography imaging systems based on linear arrays for clinical applications. The vibro-acoustography transducer is designed with two arrays driven by two continuous-wave o...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173460402600101

    authors: Silva GT,Greenleaf JF,Fatemi M

    更新日期:2004-01-01 00:00:00

  • Effective scatterer diameter estimates for broad scatterer size distributions.

    abstract::Acoustic form factors have been used to model the frequency dependence of acoustic scattering in phantoms and tissues. This work demonstrates that a broad range of scatterer sizes, individually well represented by Faran theory or a Gaussian form factor, is not accurately described by a single effective scatterer from ...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/0161734614534399

    authors: Nordberg EP,Hall TJ

    更新日期:2015-01-01 00:00:00

  • In vivo study of online liver tissue classification based on envelope power spectrum analysis.

    abstract::An ultrasonic imaging and signal analysis system, combining a 3.5 MHz linear array B-scanner and an array processor, has been realized for a clinical liver tissue classification study. Based on the complete unprocessed rf data set of a real time B-image, local envelope power spectra averaged over interactively defined...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469401600202

    authors: Lang M,Ermert H,Heuser L

    更新日期:1994-04-01 00:00:00

  • Classification of scattering objects by regular arrays of scatterers using Fourier analysis.

    abstract::For a class of scattering objects the mean separation between the scatterers is determined. Over a range of frequencies, ultrasonic back-scattered pressure signals are recorded. It is suggested to derive the mean spacing of an unknown scattering object by employing Fourier analysis and comparing the signal with signal...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173468300500405

    authors: Koch I

    更新日期:1983-10-01 00:00:00

  • Breast tissue classification using diagnostic ultrasound and pattern recognition techniques: II. Experimental results.

    abstract::The methods of statistical pattern recognition have been applied to the problem of in vivo ultrasonic characterization of breast disease in humans. Backscattered A-mode signals obtained from a commercial pulse imaging system were used to generate a large set of potentially useful features. Using statistical tests, a s...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173468300500107

    authors: Finette S,Bleier AR,Swindell W,Haber K

    更新日期:1983-01-01 00:00:00

  • Ultrasound attenuation measurements of the liver in vivo using a commercial sector scanner.

    abstract::Attenuation measurements of various tissue mimicking phantoms and three different groups of patients were obtained using a modified commercial sector scanner. Estimates of attenuation were made using the spectral shift method with mean frequencies at different depths of a region of interest being obtained by both zero...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173468400600402

    authors: Garra BS,Shawker TH,Nassi M,Russell MA

    更新日期:1984-10-01 00:00:00

  • Phase-derivative imaging. II: Effects of beam diffraction and scatterer density.

    abstract::The potential of using the phase derivative (PD) of the radio-frequency echograms for producing 2-dimensional grey scale images was further investigated. The PD images were produced by five different algorithms, which according to the results described in the companion paper yield PD images dominated by the amplitude ...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173468901100301

    authors: Oosterveld BJ,Romijn RL,Thijssen JM

    更新日期:1989-07-01 00:00:00

  • Reduction of the clutter component in Doppler ultrasound signals based on singular value decomposition: a simulation study.

    abstract::In pulsed Doppler ultrasound systems, the ultrasound radiofrequency (RF) signals received can be employed to estimate noninvasively the time-dependent blood velocity distribution within and artery. The RF signals are composed of signals originating from clutter (e.g., vessel walls) and scatterers (e.g., red blood cell...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469701900101

    authors: Ledoux LA,Brands PJ,Hoeks AP

    更新日期:1997-01-01 00:00:00

  • Acoustic Structure Quantification Analysis of the Thyroid in Patients with Diffuse Autoimmune Thyroid Disease.

    abstract::The aim of this study was to assess whether acoustic structure quantification (ASQ) can differentiate normal from pathological thyroid parenchyma in patients with diffuse autoimmune thyroid disease (AITD). We evaluated 83 subjects (72 [87%] women and 11 [13%] men) aged 19 to 94 years with a mean age of 53 years. We pe...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/0161734615580766

    authors: Zandieh S,Bernt R,Zwerina J,Haller J,Knoll P,Seyeddain O,Mirzaei S

    更新日期:2016-03-01 00:00:00

  • Frequency diversity speckle processing.

    abstract::Ultrasonic waveform data from a tissue-mimicking phantom containing low contrast targets was digitized, stored and processed prior to creating and displaying ultrasonic images. Speckle reduction was performed by digital filtering of the waveform data with appropriately spaced and weighted digital filters, prior to bot...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173468700900202

    authors: Gehlbach SM,Sommer FG

    更新日期:1987-04-01 00:00:00

  • On the feasibility of imaging peripheral nerves using acoustic radiation force impulse imaging.

    abstract::Regional anesthesia is preferred over general anesthesia for many surgical procedures; however, challenges associated with poor image guidance limit its widespread acceptance as a viable alternative. In B-mode ultrasound images, the current standard for guidance, nerves can be difficult to visualize due to their simil...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173460903100303

    authors: Palmeri ML,Dahl JJ,MacLeod DB,Grant SA,Nightingale KR

    更新日期:2009-07-01 00:00:00

  • Optimization of signal-to-noise ratio for multilayer PZT transducers.

    abstract::In medical ultrasound imaging, two-dimensional (2-D) array transducers are desirable to implement dynamic focusing and phase aberration correction in two dimensions as well as volumetric imaging. Unfortunately, the small size of a 2-D array element results in a small clamped capacitance and a large electrical impedanc...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173469501700202

    authors: Goldberg RL,Smith SW

    更新日期:1995-04-01 00:00:00

  • Optimal transmit phasing for harmonic-background suppression with bipolar square-wave pulser.

    abstract::Optimal transmit phasing has been proposed to increase contrast-to-tissue ratio (CTR) by relatively phasing the tissue and leakage harmonic components to cancel each other out for tissue-background suppression in harmonic imaging. Since most clinical systems are only equipped with a bipolar square-wave pulser, effecti...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173461003200103

    authors: Shen CC,Yang YC,Chen WS

    更新日期:2010-01-01 00:00:00

  • Observations of tissue response to acoustic radiation force: opportunities for imaging.

    abstract::Acoustic Radiation Force Impulse (ARFI) imaging is a method for characterizing local variations in tissue mechanical properties. In this method, a single ultrasonic transducer array is used to both apply temporally short localized radiation forces within tissue and to track the resulting displacements through time. In...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/016173460202400301

    authors: Nightingale K,Bentley R,Trahey G

    更新日期:2002-07-01 00:00:00

  • Assessment of Age-related Oxygenation Changes in Calf Skeletal Muscle by Photoacoustic Imaging: A Potential Tool for Peripheral Arterial Disease.

    abstract::Peripheral artery disease is often asymptomatic, and various imaging and nonimaging techniques have been used for assessment and monitoring treatments. This study is designed to demonstrate the ability of photoacoustic imaging to noninvasively determine changes in tissue oxygenation that occur in mice's hind limb skel...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/0161734619862287

    authors: Kirkham BM,Schultz SM,Ashi K,Sehgal CM

    更新日期:2019-09-01 00:00:00

  • GPU-accelerated Kernel Regression Reconstruction for Freehand 3D Ultrasound Imaging.

    abstract::Volume reconstruction method plays an important role in improving reconstructed volumetric image quality for freehand three-dimensional (3D) ultrasound imaging. By utilizing the capability of programmable graphics processing unit (GPU), we can achieve a real-time incremental volume reconstruction at a speed of 25-50 f...

    journal_title:Ultrasonic imaging

    pub_type: 杂志文章

    doi:10.1177/0161734616689464

    authors: Wen T,Li L,Zhu Q,Qin W,Gu J,Yang F,Xie Y

    更新日期:2017-07-01 00:00:00