Presence of the basement membrane component--heparan sulfate proteoglycan--in bovine lens capsules.

Abstract:

:Heparan sulfate proteoglycan was extracted from bovine lens capsules by 0.45 M NaCl/2 M urea and purified using ion-exchange chromatography and gel filtration. The proteoglycan was found to consist of protein and carbohydrate in a ratio of 75 to 25. The estimated average molecular weight of the heparan sulfate proteoglycan eluted by 0.2 M NaCl on a diethylaminoethyl (DEAE)-cellulose column was 400 kilodaltons (kDa) and that of its glycosaminoglycan was 18.8 kDa. The amino acid composition of the proteoglycan was quite similar to that of the bovine glomelular basement membrane.

authors

Onodera S

doi

10.1248/cpb.39.1059

subject

Has Abstract

pub_date

1991-04-01 00:00:00

pages

1059-61

issue

4

eissn

0009-2363

issn

1347-5223

journal_volume

39

pub_type

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