Abstract:
:We have established PCR assays for the genes coding for the major proteins of the desmosome type of cell junction, the desmosomal cadherins DGI (desmoglein) and DGII/III (desmocollins), and the plaque proteins DPI/II (desmoplakin) and DPIII (plakoglobin) and used them to test human-mouse and human-rat somatic cell hybrids with different contents of human chromosomes. From these data we were able to assign DGI to chromosome 18 (DSG), DGII/III to chromosome 9p (DSC), DPI/II to chromosome 6p21-ter(DSP), and DPIII to chromosome 7 (JUP).
journal_name
Genomicsjournal_title
Genomicsauthors
Arnemann J,Spurr NK,Wheeler GN,Parker AE,Buxton RSdoi
10.1016/0888-7543(91)90446-lsubject
Has Abstractpub_date
1991-07-01 00:00:00pages
640-5issue
3eissn
0888-7543issn
1089-8646journal_volume
10pub_type
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