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Concurrent splenic peliosis and vascular Ehlers-Danlos syndrome.

Abstract：

:This case report describes concurrent splenic peliosis and vascular Ehlers-Danlos syndrome (EDS) in a 59-year-old male patient. After splenic rupture due to peliosis, the complicated postoperative period hinted at the possibility of vascular EDS. This diagnosis was confirmed by genetic testing, which revealed a novel point mutation in the COL3A1 gene, c.2545G-->C, leading to a codon encoding for arginine instead of glycine (p.Gly849Arg). In addition, a histological diagnosis of splenic peliosis could be established.

journal_name

Ann Vasc Surg

journal_title

Annals of vascular surgery

authors

van Bon AC,Kristinsson JO,van Krieken JH,Wanten GJ

doi

10.1016/j.avsg.2008.02.004

subject

Has Abstract

pub_date

2009-03-01 00:00:00

pages

256.e1-4

issue

2

eissn

0890-5096

issn

1615-5947

pii

S0890-5096(08)00078-2

journal_volume

23

pub_type

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