Impaired implicit learning in schizophrenia.

Abstract:

:Schizophrenia patients consistently show deficits on tasks of explicit learning and memory. In contrast, their performance on implicit processing tasks often appears to be relatively intact, although most studies have focused on implicit learning of motor skills. This study evaluated implicit learning in 59 medicated schizophrenia outpatients and 43 controls using 2 different cognitive skill tasks. Participants completed a probabilistic classification task to assess procedural habit learning and an artificial grammar task to assess incidental learning of complex rule-based knowledge, as well as an explicit verbal learning and memory task. In addition to performing worse than controls on the explicit learning task, patients showed worse overall performance on the probabilistic classification task, which involves gradual learning through trial-by-trial performance feedback. However, patients and controls showed similar levels of learning on the artificial grammar task, suggesting a preserved ability to acquire complex rule-based knowledge in the absence of performance feedback. Discussion focuses on possible explanations for schizophrenia patients' poor probabilistic classification task performance.

journal_name

Neuropsychology

journal_title

Neuropsychology

authors

Horan WP,Green MF,Knowlton BJ,Wynn JK,Mintz J,Nuechterlein KH

doi

10.1037/a0012602

subject

Has Abstract

pub_date

2008-09-01 00:00:00

pages

606-17

issue

5

eissn

0894-4105

issn

1931-1559

pii

2008-11707-006

journal_volume

22

pub_type

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