Abstract:
:We present a case of collagenous colitis with evidence of terminal ileal involvement. The patient suffered from chronic watery diarrhea of three months' duration, and colonoscopy revealed a normal endoscopic appearance. Histologic examination of biopsies revealed a broad subepithelial band of collagen, with similar histologic findings in the terminal ileum. Additionally, the patient exhibited abnormalities of d-xylose and vitamin B12 absorption, although there were no clinical signs of malabsorption. Biopsy of the proximal small intestine was normal. The significance of these findings for the definition of the clinicopathologic entity of collagenous colitis and its pathogenesis are discussed.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Lewis FW,Warren GH,Goff JSdoi
10.1007/BF01297466subject
Has Abstractpub_date
1991-08-01 00:00:00pages
1161-3issue
8eissn
0163-2116issn
1573-2568journal_volume
36pub_type
杂志文章abstract::The effect of ursodeoxycholic acid (UDCA) on bile lipid composition and bile acid kinetics was evaluated in seven cholesterol gallstone patients following one month of UDCA administration (12 mg/kg/day). UDCA administration induces a significant reduction in the cholesterol saturation index (SI). After UDCA treatment,...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01324739
更新日期:1979-02-01 00:00:00
abstract::A retrospective multicenter analysis of 652 patients with chronic hepatitis C who have been treated with interferon (IFN) was performed to assess the effects of IFN on the clinical course and development of HCC. During a mean follow-up of 54.8 months, hepatocellular carcinoma (HCC) developed in 7.0% of the patients. T...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章,多中心研究
doi:10.1023/a:1013244326874
更新日期:2002-01-01 00:00:00
abstract::Pancreatic polypeptide (PP) has been shown to be released postprandially in several species. In this study we tested the efficacy of an amino acid solution (905 mOsM), 0.1 N HCl (300 mOsM), 905 mOsM NaCl, 300 mOsM glucose, corn oil, and balloon distention within the stomach, duodenum, or ileum in stimulating release o...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01391370
更新日期:1982-09-01 00:00:00
abstract::The aim of the study was to clarify whether nutrients are still capable of slowing gastric emptying following Roux-Y gastrectomy, as in normal dogs. Gastrointestinal motility and gastric emptying of acaloric and nutritive meals with different viscosities were measured in normal dogs and after a two-thirds Roux-Y gastr...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01296038
更新日期:1987-05-01 00:00:00
abstract:BACKGROUND:Heat shock protein 70-2 (HSP70-2) has a cytoprotective role in various conditions and also protects the gastric mucosa. Recently, polymorphism of HSP70-2 at position 1267 was suggested to be associated with carcinogenesis. We investigated the association of this polymorphism with the risk of gastric cancer i...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-008-0313-z
更新日期:2009-01-01 00:00:00
abstract::Irritable bowel syndrome is a frequent gastrointestinal disorder of unknown etiology. The serotonin transporter regulates the intensity and duration of serotonin signaling in the gut and is, therefore, an attractive candidate gene for irritable bowel syndrome. Previous studies investigating the 5-HTTLPR and Stin2 VNTR...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-008-0666-3
更新日期:2009-12-01 00:00:00
abstract::We describe a 28-yr-old woman who presented with severe, recurrent cholangitis due to Caroli's disease in association with congenital hepatic fibrosis. Cystic dilatation of the segmental bile ducts was diffuse, but predominated in the right lobe and left medial segment of the liver. Extended right lobectomy was follow...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01318526
更新日期:1984-04-01 00:00:00
abstract::Irritable bowel syndrome (IBS) is a common gastrointestinal disorder characterized by chronic abdominal pain and visceral hypersensitivity. In this study, resting blood pressure and heart rate were recorded in 20 IBS patients and 23 controls. We assessed pain intensity and unpleasantness to visceral and cutaneous stim...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1016424007454
更新日期:2002-08-01 00:00:00
abstract:AIM:Several models of experimental ulcerative colitis have been previously reported. To date, only one model of Crohn's colitis that was induced by trinitrobenzene sulfonic acid has been described. MATERIALS AND METHODS:Twenty-one male albino rats were divided into three groups: group I: sham control group (n = 7), gr...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-011-1697-8
更新日期:2011-10-01 00:00:00
abstract::The diagnostic values in detecting terminal ileum dysfunction using [75Se]HCAT have been assessed for two different scintigraphic techniques in 58 subjects. The measurement of [75Se]HCAT T1/2 in the enterohepatic circulation by daily gallbladder scintigraphy showed 78% sensitivity, 96% specificity, 96% positive predic...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01308176
更新日期:1992-02-01 00:00:00
abstract::Cyclin D1 plays an important role in the multi-step process of gastrointestinal tumorigenesis. We hypothesize that normal enterocytes over-expressing cyclin D1 will demonstrate a transformed phenotype. The nontumorigenic intestinal epithelial cell line, IEC-18, was transfected with the vector pMV7-CCND1, encoding cycl...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1024138605802
更新日期:2003-07-01 00:00:00
abstract::Achalasia has been described following fundoplication and is attributed to vagal nerve damage during surgery. Similarly, other traumatic events to the distal esophagus may be linked to the development of achalasia. Operative and nonoperative trauma as a possible factor in the development of achalasia was studied. A re...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-004-9577-0
更新日期:2004-11-01 00:00:00
abstract::This study tested the hypothesis that (alginic) acid may have a preferential effect on reflux in the upright position. We evaluated the effect of a compound containing alginic acid plus antacid (extra-strength Gaviscon) versus active control antacid with equal acid-neutralizing capacity on intraesophageal acid exposur...
journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF01307584
更新日期:1992-04-01 00:00:00
abstract::The clonality of gastric glands remains a controversial topic. Chimeric mouse studies suggested that all gastric glands were monoclonal. However, using the X-linked transgenic mouse model, we have suggested that most glands are polyclonal during development and that the fraction of monoclonal glands increases after bi...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/b:ddas.0000017441.06479.c8
更新日期:2004-02-01 00:00:00
abstract::Helicobacter pylori infection has been linked with gastric carcinoma. Epithelial cell proliferation is an indicator of cancer risk. The aim of this study was to assess gastric epithelial cell proliferation before and after eradication therapy and to assess the efficacy of treatment of H. pylori infection using lanzopr...
journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章
doi:10.1007/BF02212681
更新日期:1995-08-01 00:00:00
abstract::Concentration and voltage dependence of Mg transport across the rat duodenum was measured in an Ussing chamber. Mucosa (m) to serosa (s) Mg flux exhibits a cellular fraction comparable to that found for Ca. Mg sm flux is purely diffusive and probably restricted to the paracellular pathway. At all concentrations betwee...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01296406
更新日期:1991-11-01 00:00:00
abstract::In a previous study we demonstrated that patients with recently diagnosed non-insulin-dependent diabetes mellitus (NIDDM) had significantly increased gastric emptying rates of glucose solutions compared with those of nondiabetic sex- and age-matched controls. This finding of rapid gastric emptying contrasts with the d...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01296773
更新日期:1993-01-01 00:00:00
abstract::We measured suprahepatic vein and arterial partial oxygen pressure in 35 alcoholics with severe (N = 7) or mild (N = 28) histological liver damage and without evidence of clinical liver failure. The suprahepatic vein was punctured with a fine needle, using a percutaneous approach. Suprahepatic vein partial oxygen pres...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02065531
更新日期:1995-06-01 00:00:00
abstract::The interaction of [35S]methionine with hepatic tRNA in normal, carcinogen-treated, and partially hepatectomized rats was studied. tRNA was preferentially labeled following [35S]methionine (1.6 mCi, 25 mg/kg body wt) administration by intraperitoneal injection. The extent of [35S]methionine-tRNA interaction was impair...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01297152
更新日期:1991-07-01 00:00:00
abstract::Despite progress in therapeutic approaches for the elimination of hepatitis C, chronic hepatitis C virus infection remains an important cause of liver disease. Therapeutic intervention with the currently available interferon-based treatment regimens is quite successful, but treatment is difficult to tolerate and is co...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章,评审
doi:10.1007/s10620-006-9484-7
更新日期:2007-04-01 00:00:00
abstract::The prevalence of lymphocytic gastritis, a specific form of chronic gastritis characterized by infiltration of gastric superficial epithelium with T lymphocytes, has been established in nonulcer dyspepsia. Among a population sample of 586 patients at risk for gastric carcinoma, 0.83% of patients with nonulcer dyspepsi...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01297450
更新日期:1991-08-01 00:00:00
abstract:BACKGROUND:A new prepared oral viscous budesonide (PVB) has been effective in inducing clinical and histological remission in pediatric eosinophilic esophagitis (EoE). AIMS:To evaluate the efficacy of a 12-week maintenance therapy on clinical, endoscopic, and histological remission using half of the dose used in the i...
journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章
doi:10.1007/s10620-018-5449-x
更新日期:2019-06-01 00:00:00
abstract::Gastric emptying scintigraphy (GES) is usually performed for up to 2 hr to measure the gastric emptying (GE) of solids. Symptomatic patients, however, may have borderline results at 2 hr, making it difficult to determine whether a gastric motor disorder is present. The aim of this study was to assess whether extending...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1005697422454
更新日期:2001-01-01 00:00:00
abstract::Patients with previous gastric surgery for benign conditions are thought to be at increased risk for gastric cancer based on studies from Europe. Recommendations have been made to screen these patients repeatedly in order to detect early gastric cancers. We conducted a case-control study to estimate the risk in the Un...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01312941
更新日期:1984-08-01 00:00:00
abstract:BACKGROUND AND AIM:Dietary fiber shortens gut transit time, but data on the effects of fiber components (including resistant starch, RS) on intestinal contractility are limited. We have examined RS effects in male Sprague-Dawley rats fed either a high-amylose maize starch (HAMS) or a wholemeal made from high-amylose wh...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-015-3537-8
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Small intestinal bacterial overgrowth (SIBO) is regarded as the major risk factor of bacterial translocation. Few studies have investigated the direct relation between SIBO and translocation in cirrhotic patients. The purpose of this study is to examine the correlation between SIBO and bacterial DNA in the p...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-009-0870-9
更新日期:2010-05-01 00:00:00
abstract::Bile acids, such as deoxycholic acid (DC), are known to mediate some of their actions by differentially activating various protein kinase C (PKC) isoforms. This study confirms that DC induces apoptosis in gastric epithelial cells through PARP and caspase cascade activation, and examined the role of PKC in DC-induced a...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-006-9346-3
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:The use of volatile organic compounds (VOCs) in bile was recently studied and appeared promising for diagnosis of malignancy. Noninvasive diagnosis of malignant biliary strictures by using VOCs in urine has not been studied. AIM:To identify potential VOCs in urine to diagnose malignant biliary strictures. ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-015-3596-x
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND AND AIMS:Endoscopic treatment is effective in the treatment of patients with bile duct injury after cholecystectomy. We aimed to investigate the long-term results of endoscopic treatment, factors predicting the recurrence of the stricture, and to determine the optimal endoscopic treatment. METHODS:The study...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-014-3515-6
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND AND AIMS:The influence of direct-acting antivirals (DAAs) on chronic hepatitis C (CHC)-related hepatocellular carcinoma (HCC) remains controversial. We investigated the effect of eradicating CHC using DAAs on treatment outcomes in patients with CHC-related HCC treated with transarterial chemoembolization (TA...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-020-06533-7
更新日期:2020-08-28 00:00:00