Abstract:
:Because of shared routes of transmission, hepatitis C virus (HCV) coinfection is common among HIV-infected persons. Because of the effectiveness of antiretroviral therapy, chronic HCV has now emerged as a major cause of morbidity and mortality in this population. Because chronic HCV is highly prevalent among HIV-infected patients and has a rapid disease progression, antiviral therapy with pegylated interferon plus ribavirin is critical for the long-term survival of HIV/HCV-coinfected patients. In this article, the authors review the (1) epidemiology of HCV among HIV-infected individuals, (2) effect of HIV on the natural history of chronic HCV, (3) impact of antiretroviral therapy on HCV coinfection, and (4) management of chronic HCV in the HIV-infected person.
journal_name
Clin Liver Disjournal_title
Clinics in liver diseaseauthors
Lo Re V 3rd,Kostman JR,Amorosa VKdoi
10.1016/j.cld.2008.03.009subject
Has Abstractpub_date
2008-08-01 00:00:00pages
587-609, ixissue
3eissn
1089-3261issn
1557-8224pii
S1089-3261(08)00034-2journal_volume
12pub_type
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journal_title:Clinics in liver disease
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journal_title:Clinics in liver disease
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journal_title:Clinics in liver disease
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journal_title:Clinics in liver disease
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journal_title:Clinics in liver disease
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journal_title:Clinics in liver disease
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journal_title:Clinics in liver disease
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journal_title:Clinics in liver disease
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journal_title:Clinics in liver disease
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journal_title:Clinics in liver disease
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abstract::Immunoglobulin G4 (IgG4)-related sclerosing cholangitis (IgG4-SC) is the biliary manifestation of the multisystem IgG4-related disease. IgG4-SC presents with biliary strictures and/or masses that can bear a striking similarity to other malignant and inflammatory diseases. Diagnosis is based on a combination of clinica...
journal_title:Clinics in liver disease
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pub_type: 历史文章,杂志文章,评审
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journal_title:Clinics in liver disease
pub_type: 杂志文章,评审
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journal_title:Clinics in liver disease
pub_type: 杂志文章,评审
doi:10.1016/j.cld.2005.10.004
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journal_title:Clinics in liver disease
pub_type: 杂志文章,评审
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journal_title:Clinics in liver disease
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journal_title:Clinics in liver disease
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journal_title:Clinics in liver disease
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abstract::In conclusion, the natural history of chronic HCV infection has not yet been fully defined. Current data suggest that the process runs an indolent course during the first two decades after initial infection, accounting for modest morbidity and mortality. Serious sequelae are more likely to emerge as the disease proces...
journal_title:Clinics in liver disease
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journal_title:Clinics in liver disease
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journal_title:Clinics in liver disease
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journal_title:Clinics in liver disease
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