Heart rate variability in patients with major depression.

Abstract:

:We have previously reported decreased heart rate variability upon standing in panic disorder patients compared with controls. In this study, we extend our report to include patients with major depression (n = 19). Compared to normal controls (n = 20) and panic disorder patients (n = 30), there was no significant difference in the immediate changes in heart rate upon standing in the depressed group. The standing heart rate variability (R-R variability) was significantly lower in panic disorder patients compared to both normal controls and depressed patients as indicated by the corrected standard deviations, the corrected mean consecutive difference, the corrected standard deviation of the mean consecutive difference of the R-R intervals, and the high frequency variability in successive R-R intervals, suggesting an increased vagal withdrawal in panic disorder patients, especially upon standing. There was no significant difference in any of the heart rate variability measures between depressed patients and normal controls.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Yeragani VK,Pohl R,Balon R,Ramesh C,Glitz D,Jung I,Sherwood P

doi

10.1016/0165-1781(91)90104-w

subject

Has Abstract

pub_date

1991-04-01 00:00:00

pages

35-46

issue

1

eissn

0165-1781

issn

1872-7123

pii

0165-1781(91)90104-W

journal_volume

37

pub_type

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