Abstract：
BACKGROUND:Kawasaki disease is an acute, self-limited vasculitis of unknown etiology. Coronary artery involvement is the predominant complication, ranging from no involvement to dilation through to aneurysm formation. We sought to determine trends over time and associated factors for normalized coronary artery dimensions for patients with acute KD. METHODS:Clinical data and echocardiographic studies were reviewed for patients with acute Kawasaki disease over a 3 year period having standardized assessments and management strategies. Patients with echocardiograms from the initial, 6-8 week, and 1 year post-Kawasaki disease assessments were included. Coronary artery measurements were normalized for body surface area. A mixed linear regression analysis for repeated measures was used to determine trends over time. RESULTS:We included 176 patients. Based on the Japanese Ministry of Health measurement criteria 11% of patients were classified as having coronary artery abnormalities. Normalized initial measurements showed Z-scores greater than +2 for 23% of patients for any of the coronary artery branches. Particularly for initial measurements, Japanese Ministry of Health measurement criteria underestimated the prevalence of abnormalities defined by Z-scores. Time trends were noted, such that Z-scores decreased from initial values in a logarithmic manner, mostly in the first 2 to 3 months. Greater than 50% of patients with initial Z-scores within the normal range showed a decrease over time, suggesting previously unrecognized dilation. CONCLUSION:A longitudinal assessment of normalized coronary artery measurements may identify further patients with subtle coronary artery abnormalities after acute Kawasaki disease.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Crystal MA,Manlhiot C,Yeung RS,Smallhorn JF,McCrindle BWdoi
10.1016/j.ijcard.2008.04.019subject
Has Abstractpub_date
2009-07-24 00:00:00pages
27-32issue
1eissn
0167-5273issn
1874-1754pii
S0167-5273(08)00597-4journal_volume
136pub_type
杂志文章abstract：BACKGROUND:Exercise capacity following Fontan surgery is often depressed. An inability to reduce pulmonary vascular resistance appropriately during exercise may contribute to this phenomenon. The aim of this study was to determine whether administration of iloprost, a selective pulmonary vasodilator, would improve exer...
journal_title：International journal of cardiology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ijcard.2013.03.014
更新日期：2013-10-03 00:00:00
abstract：BACKGROUND:As drug-eluting stent (DES) has almost overcome the disadvantage of frequent restenosis, off-pump coronary artery bypass grafting (OPCAB) has been introduced to avoid complications of cardiopulmonary bypass. However, which approach may promise better outcomes for patients with coronary artery disease remains...
journal_title：International journal of cardiology
pub_type： 杂志文章,meta分析
doi：10.1016/j.ijcard.2014.04.182
更新日期：2014-07-01 00:00:00
abstract：:Over a period of 12 years, two cases of pulmonary arterial aneurysms were encountered in our autopsy data of 13 cases of congenital heart defects with right-sided infective endocarditis. Pulmonary arterial aneurysms are rare lesions and may be categorized as central or peripheral. Although early reports implicated tub...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(92)90247-z
更新日期：1992-06-01 00:00:00
abstract：:The in-stent thrombosis is considered as a serious complication of percutaneous coronary intervention. The impaired response to the antiplatelet therapy may play an important role in this crucial problem. Recurrent thrombosis can be explained by genetic background. Because the phenomenon of clopidogrel resistance is a...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2005.11.048
更新日期：2006-08-10 00:00:00
abstract：BACKGROUND:Treatment of heart failure patients with aldosterone antagonists has been shown to reduce the occurrence of sudden cardiac death. Therefore we aimed at determining the consequences of chronic exposure to aldosterone and the aldosterone antagonists eplerenone and spironolactone on the electrophysiological pro...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2011.06.100
更新日期：2013-04-05 00:00:00
abstract：BACKGROUND:Cardiovascular risk-prediction models are used in clinical practice to identify and treat high-risk populations, and to communicate risk effectively. We assessed the validity and utility of four cardiovascular risk-prediction models in an Asian population of a middle-income country. METHODS:Data from a nati...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2014.07.066
更新日期：2014-09-01 00:00:00
abstract：:Heart valve disease is a frequently encountered pathology, related to high morbidity and mortality rates in industrialized and developing countries. Animal models are interesting to investigate the causality, but also underlying mechanisms and potential treatments of human valvular diseases. Recently, animal models of...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/j.ijcard.2012.03.065
更新日期：2013-05-25 00:00:00
abstract：OBJECTIVES:To perform an analytical overview of the risk factors, pathogenesis of stroke and the strategies for the management of concomitant coronary artery disease and carotid artery stenosis (CAS). Four strategies were analysed; CABG in the presence of CAS, combined (CE+CABG), reverse (CABG+CE<3 months) and prior st...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/s0167-5273(00)00251-5
更新日期：2000-06-12 00:00:00
abstract：:Coronary artery disease accounts for the greatest proportion of cardiovascular diseases therefore it is the major cause of death worldwide. Its therapeutic importance is indicated by still high mortality of myocardial infarction, which is one of the most severe forms of CVDs. Moreover, the risk of developing heart fai...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/j.ijcard.2016.06.223
更新日期：2016-08-01 00:00:00
abstract：:There is controversy about the influence of QT dispersion on the incidence of early ventricular arrhythmias in patients with acute myocardial infarction (AMI). The QT and QTc dispersion (QTd, QTcd) between two groups of patients with AMI were compared: 39 patients with early sustained ventricular tachycardia or ventri...
journal_title：International journal of cardiology
pub_type： 临床试验,杂志文章
doi：10.1016/s0167-5273(97)00226-x
更新日期：1997-12-19 00:00:00
abstract：:A case of ventricular noncompaction with Giant P waves and focal atrial tachycardia is presented. A 36-year-old man was admitted to our hospital because of palpitations and a progressive worsening of heart failure. A 12 lead rest electrocardiogram showed large positive waves followed by smaller negative waves in limb ...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2006.11.149
更新日期：2008-01-11 00:00:00
abstract：INTRODUCTION:Global left ventricular (LV) afterload as assessed by valvulo-arterial impedance (Zva), may be an independent predictor of mortality in patients with severe aortic stenosis (AS) and preserved LV ejection fraction (LVEF). However, its quantification using echocardiography may be subject to error measurement...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2014.11.180
更新日期：2015-02-01 00:00:00
abstract：:Stent strut fracture (SSF) after drug-eluting stent (DES) implantation may be an important complication after DES implantation particularly in patients undergoing sirolimus eluting stent implantation. Since SSF is a highly relevant adverse event which can result in in-stent restenosis and thrombosis, we believe that D...
journal_title：International journal of cardiology
pub_type： 评论,信件
doi：10.1016/j.ijcard.2007.07.011
更新日期：2009-02-06 00:00:00
abstract：:Calcium channel blockers (CCBs) have several properties which may have beneficial effects on the development of atherosclerosis. These include inhibition of vascular smooth muscle cell (SMC) proliferation and migration; inhibition of calcium influx into the vascular wall; reduction of extracellular matrix synthesis; p...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/s0167-5273(97)00236-2
更新日期：1997-12-31 00:00:00
abstract：OBJECTIVES:Atrial electrical remodeling is considered to play an important role in the appearance of atrial fibrillation. The effect of atrial natriuretic peptide (ANP) on atrial electrical remodeling was evaluated in a canine atrial stimulation model. METHODS:In 15 beagle dogs, electrodes for pacing and recording wer...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2006.12.005
更新日期：2008-01-11 00:00:00
abstract：:A 56-year-old man without previous medical history or risk factors for coronary artery disease, presented with chest pain 2 weeks after violent blunt chest trauma. He was as a spectator, beaten and kicked almost to death during an amateur soccer match. Because of embarrassment, this was denied till shortly after his d...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/s0167-5273(97)00320-3
更新日期：1998-02-28 00:00:00
abstract：:There is concern about adverse effects on renal function in patients with prolonged cardiac intervention procedures, when contrast media is used. To investigate this further we studied changes in renal function in 104 patients (79 male, 25 female; mean age 59.2, SD 9.8) undergoing routine elective percutaneous translu...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/s0167-5273(99)00063-7
更新日期：1999-07-31 00:00:00
abstract：:Sarcoidosis is a rare granulomatous disease of unknown etiology that can affect any organ. Cardiac involvement, although uncommon, has a wide spectrum of clinical manifestations and is potentially fatal. Although there is no agreement upon a strategy for the diagnosis (which is difficult to make based on clinical info...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/j.ijcard.2003.07.024
更新日期：2004-11-01 00:00:00
abstract：:Mechanical stretch is a major determinant that leads to heart failure, which is associated with a steady increase in myocardial angiotensinogen (Aogen) expression and formation of the biological peptide angiotensin II (Ang II). c-jun NH2-terminal kinase (JNK) and p38α have been found to have opposing roles on stretch-...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2015.10.109
更新日期：2016-01-15 00:00:00
abstract：BACKGROUND:Transradial access (RA) is associated with less complications and is preferred by patients. Vascular closure devices (VCDs) may improve discomfort and may reduce complications associated with transfemoral access. Aim was to evaluate complications and discomfort associated with percutaneous coronary procedure...
journal_title：International journal of cardiology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ijcard.2008.06.045
更新日期：2009-11-12 00:00:00
abstract：BACKGROUND:Hypertension, type 2 diabetes and other cardiovascular diseases, all risk factors for atrial fibrillation, are associated with birth weight. It remains unclear, however, whether risk of atrial fibrillation is also associated with birth weight. We investigated the associations of birth weight and preterm birt...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2014.10.138
更新日期：2015-01-15 00:00:00
abstract：:The relationship between hyperlipidemia and a parental history of heart attack and other related disorders was studied in 2224 two- to 18-yr-old children in Madrid (Spain). Children were divided into three groups: those with a parental history of heart attack (first group), a parental history of stroke, hypertension, ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(92)90295-e
更新日期：1992-09-01 00:00:00
abstract：BACKGROUND:Self-reported depressive symptoms and clinical depression after myocardial infarction (MI) are both associated with poor cardiac prognosis. It is important to distinguish between the two when assessing cardiac prognosis, but few studies have done so. The present article evaluates the independent prognostic i...
journal_title：International journal of cardiology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ijcard.2012.07.002
更新日期：2013-09-10 00:00:00
abstract：BACKGROUND:While the impact of mitral regurgitation (MR) prior to transcatheter aortic valve replacement (TAVR) has been intensively studied, the implications of post-procedural MR on outcome are unknown. We investigated the clinical and physiological impact of significant MR after TAVR. METHODS:Clinical and echocardi...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2019.07.092
更新日期：2020-01-15 00:00:00
abstract：BACKGROUND:The results of studies investigating the clinical benefit of a direct stenting (DS) strategy in ST-elevation myocardial infarction (STEMI) are inconsistent and data regarding cardiac magnetic resonance (CMR) parameters of myocardial injury are lacking. The aim of this study was to investigate the effect of D...
journal_title：International journal of cardiology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ijcard.2018.11.141
更新日期：2019-05-15 00:00:00
abstract：BACKGROUND:Meta-analyses have suggested that remote telemedical management (RTM) positively affects clinical outcomes in chronic HF patients. The results of two recent randomised RTM trials do not corroborate these results. We aim to report prospectively defined and exploratory subgroup analyses for the TIM-HF trial an...
journal_title：International journal of cardiology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ijcard.2011.09.007
更新日期：2012-11-29 00:00:00
abstract：:The cardiology and field of cardiovascular approaches are often mentioned as of the earliest concerns throughout the history of mankind civilization. During the golden ages of Islamic era, 9th to 12th centuries A.D., medical knowledge from various fields including cardiology was flourished by prominent Persian physici...
journal_title：International journal of cardiology
pub_type： 传,历史文章
doi：10.1016/j.ijcard.2014.12.145
更新日期：2015-03-01 00:00:00
abstract：:Autoimmune disease is characterised by the presence of circulating autoantibodies in the affected patients and in a proportion of their relatives. These antibodies are generally not pathogenic but are reliable markers of immune-mediated tissue damage. In organ-specific autoimmune disease, the destruction process is la...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/0167-5273(96)02593-4
更新日期：1996-05-01 00:00:00
abstract：:The purpose of this study was to examine the value of marked left axis deviation in men without apparent heart disease in the assessment of ischemic heart disease risk. In the Manitoba Study, a cohort of 3983 men who were predominantly between 25 to 34 yr of age at entry in 1948, 247 cases of marked left axis deviatio...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(81)90030-9
更新日期：1981-01-01 00:00:00
abstract：:We present a patient with Brugada syndrome and paroxysmal atrial fibrillation who underwent circumferential pulmonary vein isolation. His electrocardiogram showed normal sinus rhythm and first-degree AV block (P-R 280 ms) with coved-type ST elevation in V1-2 (+2.0 mm) before ablation. During ablation around the left p...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2009.04.010
更新日期：2011-06-02 00:00:00
