Mechanistic studies of sodium pump.

Abstract:

:Sodium pump was the first ion pump discovered. A member of the family of active transporters that catalyze adenosine 5'-triphosphate hydrolysis by forming a phosphorylated enzyme intermediate, sodium pump couples the energy released to unequal countertransport of sodium and potassium ions. The ion gradient generated by the pump is important for a variety of secondary physiological processes ranging from metabolite transport to electrical excitation of nerve and muscle. Selected experiments relating structure to function are reviewed.

journal_name

Arch Biochem Biophys

authors

Faller LD

doi

10.1016/j.abb.2008.05.017

subject

Has Abstract

pub_date

2008-08-01 00:00:00

pages

12-21

issue

1

eissn

0003-9861

issn

1096-0384

pii

S0003-9861(08)00278-6

journal_volume

476

pub_type

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